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anti-TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) Antibodies

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Additionally we are shipping TAF4 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TAF4 6874 O00268
TAF4    
TAF4    
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Top anti-TAF4 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated ChIP, WB WB Suggested Anti-TAF4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using TAF4 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of TAF[II] 135 on Jurkat lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of anti-TAF[II] 135. Immunofluorescent staining of HeLa cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Mouse Un-conjugated DB   50 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (35.57 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated DB, WB   100 μg Log in to see 11 to 16 Days
$583.00
Details
Human Rabbit Un-conjugated ELISA   100 μL Log in to see 8 to 10 Days
$478.50
Details

TAF4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine)
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Chicken


Top referenced anti-TAF4 Antibodies

  1. Human Monoclonal TAF4 Primary Antibody for IF, WB - ABIN968728 : Freiman, Albright, Chu, Zheng, Liang, Sha, Tjian: Redundant role of tissue-selective TAF(II)105 in B lymphocytes. in Molecular and cellular biology 2002 (PubMed)
    Show all 4 references for ABIN968728

  2. Chicken Polyclonal TAF4 Primary Antibody for ChIP, WB - ABIN2777910 : Liu, Coleman, Grob, King, Florens, Washburn, Geles, Yang, Ramey, Nogales, Tjian: Structural changes in TAF4b-TFIID correlate with promoter selectivity. in Molecular cell 2008 (PubMed)

  3. Human Polyclonal TAF4 Primary Antibody for ELISA, WB - ABIN1533475 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

More Antibodies against TAF4 Interaction Partners

Fruit Fly (Drosophila melanogaster) TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) interaction partners

  1. Daat suggest that holo-TFIID (show TAF8 Antibodies) comprises a stable core subcomplex containing TAF4, TAF5 (show TAF5 Antibodies), TAF6 (show TAF6 Antibodies), TAF9 (show TAF9 Antibodies), and TAF12 (show TAF12 Antibodies) decorated with peripheral subunits TAF1 (show TAF1 Antibodies), TAF2 (show TAF2 Antibodies), TAF11, and TBP (show TBP Antibodies).

Human TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) interaction partners

  1. TAF4 isoforms generated by the alternative splicing participate in the conversion of the cellular transcriptional programs from the maintenance of stem cell state to differentiation

  2. These interactions are important to the transcriptional activation of these genes by Rta (show RBM9 Antibodies) since introducing TAF4 shRNA substantially reduces the ability of Rta (show RBM9 Antibodies) to activate these promoters

  3. huntingtin (show HTT Antibodies) interacts with Sp1 (show PSG1 Antibodies) and TAFII130; transcriptional activity of SP1 (show PSG1 Antibodies) and TAFII130 disrupted in early Huntingtin's Disease

  4. Data present the crystal structure of a complex formed by the interacting domains from two subunits of the general transcription factor TFIID, the human TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20).

  5. TAF4b incorporation into TFIID induces an open conformation at the lobe involved in TFIIA & putative activator interactions, correlating with differential activator-dependent transcription & promoter recognition by 4b/4-IID.

  6. Findings suggest that DNA binding by TAF4/4b-TAF12 facilitates the association of TFIID with the core promoter of a subset of genes.

TAF4 Antigen Profile

Protein Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases.

Gene names and symbols associated with TAF4

  • TBP-associated factor 4 (Taf4) antibody
  • protein synthesis (TAF4) antibody
  • TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa (TAF4) antibody
  • TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa (taf4) antibody
  • CG5444 antibody
  • d110 antibody
  • Dmel\\CG5444 antibody
  • dmTAF4 antibody
  • dTAF4 antibody
  • dTAFII110 antibody
  • dTAF[[II]]110 antibody
  • l(3)72Dj antibody
  • p110 antibody
  • SR3-3 antibody
  • SY3-2 TAF110 antibody
  • TAF antibody
  • TAF2C antibody
  • TAF2C1 antibody
  • TAF4 antibody
  • TAF4A antibody
  • taf110 antibody
  • TAFII110 antibody
  • TAFII130 antibody
  • TAFII135 antibody
  • TAF[II]110 antibody
  • TAF[[II]] antibody
  • Taf[[II]]110 antibody
  • TFIID antibody
  • TFIID 110 antibody

Protein level used designations for TAF4

CG5444-PA , CG5444-PB , CG5444-PC , CG5444-PD , CG5444-PE , CG5444-PF , CG5444-PG , CG5444-PH , TATA-associated factor 110 , TBP associated factor 110 , TBP-associated factor , TBP-associated factor 110 , TBP-associated factor 110kD , Taf4-PA , Taf4-PB , Taf4-PC , Taf4-PD , Taf4-PE , Taf4-PF , Taf4-PG , Taf4-PH , lethal(3)72Dj , hypothetical protein , RNA polymerase II TBP-associated factor subunit C , TAF(II)130 , TAF(II)135 , TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD , TAFII-130 , TAFII-135 , TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD , TBP-associated factor 4 , transcription initiation factor TFIID 130 kDa subunit , transcription initiation factor TFIID 135 kD subunit , transcription initiation factor TFIID 135 kDa subunit , transcription initiation factor TFIID subunit 4

GENE ID SPECIES
39765 Drosophila melanogaster
3645198 Candida albicans SC5314
6874 Homo sapiens
100037075 Xenopus laevis
419223 Gallus gallus
477280 Canis lupus familiaris
100626452 Sus scrofa
789854 Bos taurus
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