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TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. Additionally we are shipping and many more products for this protein.
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Human Polyclonal TAF4B Primary Antibody for FACS, WB - ABIN656097
Kalogeropoulou, Voulgari, Kostourou, Sandaltzopoulos, Dikstein, Davidson, Tora, Pintzas: TAF4b and Jun/activating protein-1 collaborate to regulate the expression of integrin alpha6 and cancer cell migration properties. in Molecular cancer research : MCR 2010
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Human Polyclonal TAF4B Primary Antibody for EIA, WB - ABIN955068
Gazit, Moshonov, Elfakess, Sharon, Mengus, Davidson, Dikstein: TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes. in The Journal of biological chemistry 2009
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Two candidate loci in each family and homozygous truncating mutations p.R611X in TAF4B in family 1 and p.K507Sfs*3 in ZMYND15 in family 2, were identified.
We show evidence for the first time of an interdependence of TAF4b and AP-1 (show FOSB Antibodies) family members in cell type-specific promoter recognition and initiation of transcription in the context of cancer progression and EMT (show ITK Antibodies).
histone fold domain mediated interaction enhances the DNA binding activity of each of the TAF6 (show TAF6 Antibodies)-TAF9 (show TAF9 Antibodies) and TAF4b-TAF12 (show TAF12 Antibodies) pairs and of a histone-like octamer complex composed of the four TAFs
work suggests that pre-mRNA processing (show PRPF39 Antibodies) and post-translational modification represent two important regulatory steps for the gonad-specific functions of human TAF(II)105
TAF4b incorporation into TFIID induces an open conformation at the lobe involved in TFIIA & putative activator interactions, correlating with differential activator-dependent transcription & promoter recognition by 4b/4-IID.
Expression of the TAF4b gene is induced by MYC (show MYC Antibodies) through a non-canonical, but not canonical, E-box which contributes to its specific response to MYC (show MYC Antibodies).
Findings suggest that DNA binding by TAF4/4b-TAF12 facilitates the association of TFIID with the core promoter of a subset of genes.
TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells.
, TATA box binding protein (TBP)-associated factor 4B
, TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD
, transcription initiation factor TFIID 105 kD subunit
, transcription initiation factor TFIID 105 kDa subunit
, transcription initiation factor TFIID subunit 4B