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The product of TAF5L belongs to the WD-repeat TAF5 family of proteins. Additionally we are shipping TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa Antibodies (47) and and many more products for this protein.
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p300 (show EP300 Proteins) can acetylate DNA-bound Myc:Max complexes and that acetylated Myc:Max heterodimers efficiently interact with Miz-1 (show ZBTB17 Proteins)
The TAF5L gene on chromosome 1q42 is associated tie type 1 diabetes in Russian patients.
p300 (show EP300 Proteins) or PCAF (show KAT2B Proteins) maintains myoblast viability as effectively as added growth factors through mechanisms requiring the acetyltransferase activity of PCAF (show KAT2B Proteins) but not of p300 (show EP300 Proteins).
latent cytoplasmic coactivator TORC2 (show CRTC2 Proteins) mediates target gene activation in response to cAMP signaling by associating with CBP/p300 (show CREBBP Proteins) and increasing its recruitment to a subset of CREB (show CREB1 Proteins) target genes
PCAF (show KAT2B Proteins) is a histone acetyltransferase which regulates gene transcription. PCAF (show KAT2B Proteins) interacts physically and functionally with PTEN. PTEN acetylation by PCAF (show KAT2B Proteins) block the ability of PTEN to downregulate PI3-K (show PIK3CA Proteins) signalling and to induce G1 cell cycle arrest.
The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
, TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
, TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L-like
, PCAF associated factor 65 beta
, PCAF-associated factor 65 beta