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TAP Binding Protein (Tapasin) (TAPBP) ELISA Kits

TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. Additionally we are shipping TAPBP Antibodies (47) and TAPBP Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TAPBP 21356 Q9R233
Anti-Human TAPBP TAPBP 6892 O15533
TAPBP 25217  
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Top TAPBP ELISA Kits at antibodies-online.com

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Rat
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$785.71
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Mouse
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Rabbit
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Dog
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$801.43
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Guinea Pig
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Goat
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Pig
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Cow
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$817.14
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Chicken
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Monkey
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$817.14
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More ELISA Kits for TAPBP Interaction Partners

Mouse (Murine) TAP Binding Protein (Tapasin) (TAPBP) interaction partners

  1. Absence of Tpn or ERAAP independently altered the peptide repertoire by causing loss as well as gain of new pMHC I. Tpn defined the characteristic carboxy termini of canonical MHC I peptides.

  2. modification of Tapasin can enhance the presentation of targeting antigens via intracellular delivery to DCs and elicit specific CTL immune responses efficiently

  3. Data show that tapasin expression is enhanced by beta 2-microglobulin (show B2M ELISA Kits) via both transcriptional and post-transcriptional mechanisms.

  4. Deletion of a loop within the tapasin C-terminal Ig-like domain (Delta334-342) prevented tapasin association with the MHC class I molecule K(d).

  5. E2F1 (show E2F1 ELISA Kits) is an essential transcription factor for tapasin.

  6. showed that a large disulfide-bonded complex was present in the mouse cells that included ERp57 (show PDIA3 ELISA Kits), tapasin, and K(d).

  7. Role of tapasin in MHC class I antigen presentation in vivo.

  8. Data show that cell surface expression of TAP-independent class I complexes is modulated by tapasin levels and is enhanced by interferon-gamma (show IFNG ELISA Kits).

  9. tapasin has a essential function of tapasin in quality control of HLA-G (show HLAG ELISA Kits) molecules

  10. A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.

Human TAP Binding Protein (Tapasin) (TAPBP) interaction partners

  1. reduction in tapasin expression is associated with tumor progression in colorectal cancer

  2. Data suggest that tapasin (Tsn) binds to MHC I with suboptimal cargo and thereby adjusts the energy landscape in favor of MHC I complexes with immunodominant epitopes.

  3. TAP/TPN complex formation is driven by hydrophobic interactions via leucine zipper-like motifs.

  4. TAP2 (show TAP2 ELISA Kits), HLA-DOA (show HLA-DOA ELISA Kits), HLA-DOB (show HLA-DOB ELISA Kits), and tapasin loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  5. Analysis of expression of tapasin and/or HLA-I may be of value as prognostic tool for glioblastoma multiforme patients, especially when considering immunotherapy.

  6. Modified TAPBP gene function may contribute to the development of refractory chronic rhinosinusitis via reduction of circulating CD8 (show CD8A ELISA Kits) lymphocytes.

  7. Targeted re-sequencing identified rs3106189 at the 5' UTR (show UTS2R ELISA Kits) of TAPBP and rs1052918 at the 3' UTR (show UTS2R ELISA Kits) of TCF3 (show TCF3 ELISA Kits) to be associated with the overall survival of colorectal cancer patients.

  8. the data indicate that TAPBPR and tapasin bind in a similar orientation to the same face of MHC class I.

  9. TAPBP polymorphisms may play a role in the development of aspirin-exacerbated respiratory disease.

  10. isoform lacking exon 3 affects MHC class I-peptide binding

TAPBP Antigen Profile

Antigen Summary

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene names and symbols associated with TAPBP

  • TAP binding protein (tapbp) antibody
  • tapasin (tapbp) antibody
  • TAP binding protein (TAPBP) antibody
  • TAP binding protein (Tapbp) antibody
  • TAP binding protein (tapasin) (TAPBP) antibody
  • TAP binding protein (tapasin) (Tapbp) antibody
  • D17Wsu91e antibody
  • mhc1uda antibody
  • mhc1ufa antibody
  • NGS17 antibody
  • SI:dZ179B20.1 antibody
  • SI:dZ179B20.3 antibody
  • SI:dZ179B20.7 antibody
  • TAPA antibody
  • TAPBP antibody
  • TPN antibody
  • TPSN antibody
  • zgc:109814 antibody

Protein level used designations for TAPBP

tapasin , TAP binding protein , TAP-associated protein , TAP-binding protein , TPSN , NGS-17 , TPN

GENE ID SPECIES
30163 Danio rerio
100136493 Salmo salar
100170652 Ovis aries
21356 Mus musculus
6892 Homo sapiens
504335 Bos taurus
25217 Rattus norvegicus
417048 Gallus gallus
481740 Canis lupus familiaris
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