You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-TAP Binding Protein (Tapasin) (TAPBP) Antibodies

TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. Additionally we are shipping TAPBP Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TAPBP 21356 Q9R233
TAPBP 6892 O15533
TAPBP 25217  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-TAPBP Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TAPBP Antibody Titration: 0.2-1 ug/mlPositive Control: 293T cell lysate WB Suggested Anti-TAPBP  Antibody Titration: 0.2-1 µg/mL  Positive Control:.93T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TAPBP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: OVCAR-3 cell lysate WB Suggested Anti-TAPBP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: OVCAR-3 cell lysate  TAPBP is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB TAPBP Antibody (N-term)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TAPBP antibody detected the TAPBP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Tapasin staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibod 200 μL Log in to see 9 Days
$487.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Cow Rabbit Un-conjugated IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$676.50
Details

TAPBP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,


, , , , ,
Rat (Rattus)


Top referenced anti-TAPBP Antibodies

  1. Cow (Bovine) Polyclonal TAPBP Primary Antibody for IHC, WB - ABIN2782218 : Facoetti, Nano, Zelini, Morbini, Benericetti, Ceroni, Campoli, Ferrone: Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors. in Clinical cancer research : an official journal of the American Association for Cancer Research 2005 (PubMed)

  2. Human Polyclonal TAPBP Primary Antibody for IHC, IHC (p) - ABIN4357823 : Sokol, Koelzer, Rau, Karamitopoulou, Zlobec, Lugli: Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. in Journal of translational medicine 2015 (PubMed)

More Antibodies against TAPBP Interaction Partners

Mouse (Murine) TAP Binding Protein (Tapasin) (TAPBP) interaction partners

  1. Absence of Tpn or ERAAP independently altered the peptide repertoire by causing loss as well as gain of new pMHC I. Tpn defined the characteristic carboxy termini of canonical MHC I peptides.

  2. modification of Tapasin can enhance the presentation of targeting antigens via intracellular delivery to DCs and elicit specific CTL immune responses efficiently

  3. Data show that tapasin expression is enhanced by beta 2-microglobulin (show B2M Antibodies) via both transcriptional and post-transcriptional mechanisms.

  4. Deletion of a loop within the tapasin C-terminal Ig-like domain (Delta334-342) prevented tapasin association with the MHC class I molecule K(d).

  5. E2F1 (show E2F1 Antibodies) is an essential transcription factor for tapasin.

  6. showed that a large disulfide-bonded complex was present in the mouse cells that included ERp57 (show PDIA3 Antibodies), tapasin, and K(d).

  7. Role of tapasin in MHC class I antigen presentation in vivo.

  8. Data show that cell surface expression of TAP-independent class I complexes is modulated by tapasin levels and is enhanced by interferon-gamma (show IFNG Antibodies).

  9. tapasin has a essential function of tapasin in quality control of HLA-G (show HLAG Antibodies) molecules

  10. A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.

Human TAP Binding Protein (Tapasin) (TAPBP) interaction partners

  1. The results demonstrated that the mRNA expression levels of tapasin were significantly downregulated in patients with chronic hepatitis B (CHB) compared with in healthy controls and patients with acute hepatitis B Furthermore, the apoptotic rate of CD8 (show CD8A Antibodies)+ T cells was increased in patients with CHB compared with in the other two groups.

  2. The disruption of TAP1 (show TAP1 Antibodies) and TAPBP generates pluripotent embryonic stem cells with reduced immunogenicity.

  3. Fluctuation and entropy analyses show how tapasin chaperones major histocompatibility complex class I by stabilising it in a peptide-receptive conformation.

  4. reduction in tapasin expression is associated with tumor progression in colorectal cancer

  5. Data suggest that tapasin (Tsn) binds to MHC I with suboptimal cargo and thereby adjusts the energy landscape in favor of MHC I complexes with immunodominant epitopes.

  6. TAP/TPN complex formation is driven by hydrophobic interactions via leucine zipper-like motifs.

  7. TAP2 (show TAP2 Antibodies), HLA-DOA (show HLA-DOA Antibodies), HLA-DOB (show HLA-DOB Antibodies), and tapasin loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  8. Analysis of expression of tapasin and/or HLA-I may be of value as prognostic tool for glioblastoma multiforme patients, especially when considering immunotherapy.

  9. Modified TAPBP gene function may contribute to the development of refractory chronic rhinosinusitis via reduction of circulating CD8 (show CD8A Antibodies) lymphocytes.

  10. Targeted re-sequencing identified rs3106189 at the 5' UTR (show UTS2R Antibodies) of TAPBP and rs1052918 at the 3' UTR (show UTS2R Antibodies) of TCF3 (show TCF3 Antibodies) to be associated with the overall survival of colorectal cancer patients.

TAPBP Antigen Profile

Protein Summary

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene names and symbols associated with TAPBP

  • TAP binding protein (tapbp) antibody
  • tapasin (tapbp) antibody
  • TAP binding protein (TAPBP) antibody
  • TAP binding protein (Tapbp) antibody
  • TAP binding protein (tapasin) (TAPBP) antibody
  • TAP binding protein (tapasin) (Tapbp) antibody
  • D17Wsu91e antibody
  • mhc1uda antibody
  • mhc1ufa antibody
  • NGS17 antibody
  • SI:dZ179B20.1 antibody
  • SI:dZ179B20.3 antibody
  • SI:dZ179B20.7 antibody
  • TAPA antibody
  • TAPBP antibody
  • TPN antibody
  • TPSN antibody
  • zgc:109814 antibody

Protein level used designations for TAPBP

tapasin , TAP binding protein , TAP-associated protein , TAP-binding protein , TPSN , NGS-17 , TPN

GENE ID SPECIES
30163 Danio rerio
100136493 Salmo salar
100170652 Ovis aries
21356 Mus musculus
6892 Homo sapiens
504335 Bos taurus
25217 Rattus norvegicus
417048 Gallus gallus
481740 Canis lupus familiaris
Selected quality suppliers for anti-TAPBP (TAPBP) Antibodies
Did you look for something else?