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TATA Box Binding Protein Proteins (TBP)

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Additionally we are shipping TBP Antibodies (127) and TBP Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TBP 6908 P20226
TBP 21374 P29037
Rat TBP TBP 117526  
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Top TBP Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Yeast His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Methanococcus His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Archaeoglobus fulgidus His tag   1 mg Log in to see 56 to 66 Days
$2,432.83
Details
Yeast Thermococcus sibiricus His tag   1 mg Log in to see 56 to 66 Days
$2,440.17
Details
Yeast Methanopyrus kandleri His tag   1 mg Log in to see 56 to 66 Days
$2,440.17
Details
Yeast Pyrococcus His tag   1 mg Log in to see 56 to 66 Days
$2,458.50
Details

TBP Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)
,

More Proteins for TATA Box Binding Protein (TBP) Interaction Partners

Fruit Fly (Drosophila melanogaster) TATA Box Binding Protein (TBP) interaction partners

  1. TFIID (show TAF8 Proteins) has two disctinct modes of transcription initiation, de novo initiation and reinitiation, as revealed by the inhibitory effect of TFIID (show TAF8 Proteins)-bound tin (show MSH2 Proteins) compounds on the de novo initiation, but not on the reinitiation.

  2. Deactivation of TBP contributes to SCA17 pathogenesis.

  3. Aptamers generated by both selections were able to bind specifically to TBP, but the two groups showed characteristics which were clearly different in terms of their capability to compete with TATA-DNA.

  4. in fruit flies, different classes of RNA polymerase III promoters differentially utilize TBP and TRF1 (show TERF1 Proteins) for the initiation of transcription.

  5. Tbp targets core histone transcription.

  6. TBP activates TATA-dependent transcription and represses DPE-dependent transcription, whereas Mot1 and NC2 (show GTF2H5 Proteins) block TBP function and thus repress TATA-dependent transcription and activate DPE-dependent transcription.

Human TATA Box Binding Protein (TBP) interaction partners

  1. Study could not determine a definitive cutoff value for the pathologic CAG repeat (show CELF3 Proteins) number of SCA17.

  2. TBP attenuates Msx1 (show MSX1 Proteins)-mediated glycoprotein hormone alpha (show CGA Proteins) transcriptional repression.

  3. this analysis of the 2.2-kb doubly spliced RNA (2.2DS-RNA) -mediated suppression of viral RNA expression showed that 2.2DS-RNA inhibited transcription via binding to the TATA-binding protein and stress granule proteins.

  4. Our results provide first evidence that Taspase1 processing affects TFIIA (show GTF2A1 Proteins) regulation of TFIID and suggest that Taspase1 processing of TFIIA (show GTF2A1 Proteins) is required to establish INR (show INSR Proteins)-selective core promoter activity in the presence of NC2 (show GTF2H5 Proteins).

  5. TBP (and GATA2 (show GATA2 Proteins) and Sp1 (show PSG1 Proteins)) have key roles in inflammation and ischemia-like conditions through MAOA (show MAOA Proteins) regulation.

  6. Deactivation of TBP contributes to SCA17 pathogenesis.

  7. HOXA2 (show HOXA2 Proteins) acts as a suppressor or TBP-antagonist to inhibit MMP-9 (show MMP9 Proteins) expression; while methylation-mediated inactivation of HOXA2 (show HOXA2 Proteins) in NPC (show NPC1 Proteins) derepresses MMP-9 (show MMP9 Proteins) production and increases invasion of NPC (show NPC1 Proteins) cells.

  8. The data reveal synergistic effects of H3K4me3, H3K14ac and a TATA box sequence on TFIID binding in vitro. Stoichiometry analyses of affinity purified human TFIID identified the presence of a stable dimeric core.

  9. The UL4 protein directly interacted with the host TBP and the carboxy-terminal domain of RNA polymerase II in infected cells.

  10. Findings indicate that using TATA-binding protein (TBP) alone or in combination with hydroxymethylbilane synthase (HMBS (show HMBS Proteins)) as endogenous controls could be a reliable method for normalizing qRT-PCR data in hepatoma cell lines treated with TNF-alpha (show TNF Proteins).

Zebrafish TATA Box Binding Protein (TBP) interaction partners

  1. TBP plays an important role in the degradation of a specific subset of maternal mRNAs during late blastulation/early gastrulation, which involves targets of the miR (show MYLIP Proteins)-430 pathway.

Mouse (Murine) TATA Box Binding Protein (TBP) interaction partners

  1. The large TBP polyQ repeat decreases the association of MyoD (show MYOD1 Proteins) with TBP and DNA promoters and causes muscle degeneration in spinocerebellar ataxia (show USP14 Proteins) 17 transgenic mice.

  2. Thus, modulating the levels of both Huwe1 and USP10 (show USP10 Proteins) appears to fine-tune the requisite degradation of TBP during myogenesis.

  3. This study demonistrated that denervation-induced muscle atrophy on Tbp expression in mice.

  4. The results of this study confirmed motor deficits in the Tbp/Q71 mice and present previously unrecognized behavioral characteristics obtained from the automated home cage, indicating its use for high-throughput screening and testing.

  5. TBP might be a marker for transmitting cellular memory to daughter cells.

  6. we show that the differentiation of fetal liver progenitors to adult hepatocytes involves a wholesale depletion of canonical cofactor required for Sp1 (show SP1 Proteins) activation/Mediator and TFIID complexes at both the RNA and protein level

  7. Alcohol induces RNA polymerase III-dependent transcription through c-Jun (show JUN Proteins) by co-regulating TATA-binding protein (TBP) and Brf1 (show ZFP36L1 Proteins) expression.

  8. Data show that down-regulation of TrkA (show NTRK1 Proteins) also occurs in the cerebellum of SCA17 transgenic mice prior to Purkinje cell degeneration (show AGTPBP1 Proteins).

  9. Developmental specificity of recruitment of TBP to the TATA box of the human gamma-globin gene

  10. TBP N terminus functions in transcriptional regulation of a placental beta2m-dependent process that favors maternal immunotolerance of pregnancy.

Pig (Porcine) TATA Box Binding Protein (TBP) interaction partners

  1. Spermatozoa isolated from semen samples of boars contained all transcripts investigated, whereas oocytes contained only CREM (show CREM Proteins), H1, TAF1 (show TAF1 Proteins), and TBP mRNAs.

TBP Protein Profile

Protein Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TATA Box Binding Protein Proteins (TBP)

  • TATA binding protein (Tbp)
  • TATA box binding protein (TBP)
  • TATA box binding protein (tbp)
  • TATA box binding protein (tbp-a)
  • TATA box binding protein (Tbp)
  • TATA-box-binding protein (Tbp)
  • CG9874 protein
  • Dmel\\CG9874 protein
  • dtbp protein
  • dTFIID protein
  • fd20h06 protein
  • Gtf2d protein
  • gtf2d1 protein
  • HDL4 protein
  • RBP protein
  • sca17 protein
  • si:zc101n13.2 protein
  • tbp protein
  • TBP1 protein
  • TBP38 protein
  • tfiid protein
  • tfiidtau protein
  • wu:fd20h06 protein
  • xtbp protein
  • zgc:66213 protein

Protein level used designations for TATA Box Binding Protein Proteins (TBP)

42kDa polypeptide , CG9874-PA , TATA box binding protein , TATA box-binding protein , TATA-binding protein , TATA-box binding protein , Tbp-PA , TATA binding protein , TATA-box-binding protein , TATA sequence-binding protein , TATA-box binding protein N-terminal domain , TATA-box factor , transcription initiation factor TFIID TBP subunit , TATA-binding factor , zTBP , zfTBF , transcription factor , TA-TA binding protein 1 , TFIID core protein , Transcription initiation factor TFIID TBP subunit

GENE ID SPECIES
37476 Drosophila melanogaster
431689 Canis lupus familiaris
696258 Macaca mulatta
738472 Pan troglodytes
100101451 Takifugu rubripes
100380389 Salmo salar
6908 Homo sapiens
368882 Danio rerio
399465 Xenopus laevis
395995 Gallus gallus
611193 Canis lupus familiaris
516578 Bos taurus
21374 Mus musculus
117526 Rattus norvegicus
100144760 Ovis aries
780434 Sus scrofa
101839769 Mesocricetus auratus
692612 Bombyx mori
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