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TBC1 Domain Family, Member 15 Proteins (TBC1D15)

TBC1D15 encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. Additionally we are shipping TBC1D15 Antibodies (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TBC1D15 64786 Q8TC07
TBC1D15 66687 Q9CXF4
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Top TBC1D15 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details

TBC1D15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

More Proteins for TBC1 Domain Family, Member 15 (TBC1D15) Interaction Partners

Human TBC1 Domain Family, Member 15 (TBC1D15) interaction partners

  1. Demonstrate that TBC1D15 and TBC1D17 (show TBC1D17 Proteins) mediate proper autophagic encapsulation of mitochondria by regulating Rab7 (show RAB7B Proteins) activity at the interface between mitochondria and isolation membranes.

  2. TBC1D15 is required for the accumulation of RhoA (show RHOA Proteins).

  3. Fis1 (show FIS1 Proteins) acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology.

  4. although only TBC1D15/Rab7-GAP altered Rab7 (show RAB7B Proteins)-GTP (show AK3 Proteins) levels, both Rab7-GAP and mVps39 regulate lysosomal morphology and play a role in maintaining growth factor dependence

  5. This paper primarily describes (show RAB7B Proteins)mouse TBC1D15 but also reports the primary structure of human TBC1D15.

Mouse (Murine) TBC1 Domain Family, Member 15 (TBC1D15) interaction partners

  1. identify TBC1D15 as a Numb (show NUMB Proteins)-associated protein and demonstrate that its amino-terminal domain disengages p53 (show TP53 Proteins) from Numb (show NUMB Proteins), triggering p53 (show TP53 Proteins) proteolysis and promoting self-renewal and pluripotency

  2. although only TBC1D15/Rab7-GAP altered Rab7 (show RAB7A Proteins)-GTP (show AK3 Proteins) levels, both Rab7-GAP and mVps39 regulate lysosomal morphology and play a role in maintaining growth factor dependence

  3. TBC1D15 may be involved in Rab7 (show RAB7A Proteins)-mediated late endosomal trafficking

TBC1D15 Protein Profile

Protein Summary

This gene encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. The encoded protein interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with TBC1D15

  • TBC1 domain family, member 15 (TBC1D15)
  • TBC1 domain family, member 15 (Tbc1d15)
  • 4432405K22Rik protein
  • AU022358 protein
  • AU023730 protein
  • AW557774 protein
  • Ly6dl protein
  • Rab7-GAP protein

Protein level used designations for TBC1D15

GAP for RAB7 , GTPase-activating protein RAB7 , TBC1 domain family member 15 , Tre-2-budding uninhibited by benzimidazole-cell division cycle 16 domain, domain family member 15 , Tre2/Bub2/Cdc16 domain family member 15 , lymphocyte antigen 6, locus D ligand

GENE ID SPECIES
64786 Homo sapiens
66687 Mus musculus
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