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May act as a GTPase-activating protein for Rab family protein(s).. Additionally we are shipping TBC1D5 Antibodies (8) and many more products for this protein.
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TBC1D5 and the AP2 complex (show AP2B1 Proteins) are important novel regulators of the rerouting of ATG9 (show ATG9A Proteins)-containing vesicular carriers toward sites of autophagosome formation.
Membrane recruitment of the cargo-selective retromer subcomplex VPS35 (show vps35 Proteins)/29/26 is catalysed by the small GTPase (show RACGAP1 Proteins) Rab7 (show RAB7B Proteins) and inhibited by the Rab (show HRB Proteins)-GAP TBC1D5.
TBC1D5 shuttling to autophagosomes during metabolic stress facilitates retromer-dependent GLUT1 (show SLC2A1 Proteins) trafficking.
May act as a GTPase-activating protein for Rab family protein(s).
TBC1 domain family member 5