T-Box 20 (TBX20) ELISA Kits

TBX20 encodes a T-box family member. Additionally we are shipping TBX20 Antibodies (29) and TBX20 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TBX20 TBX20 57057 Q9UMR3
Anti-Mouse TBX20 TBX20 57246 Q9ES03
Anti-Rat TBX20 TBX20 315497  
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More ELISA Kits for TBX20 Interaction Partners

Zebrafish T-Box 20 (TBX20) interaction partners

  1. Tbx20 activity needs to be tightly fine-tuned to guarantee regular cardiomyocyte proliferation and embryonic heart growth in vivo.

  2. the identification of a zebrafish tbx20 mutation that results in an inactive, truncated protein lacking any functional domains, is reported.

  3. data demonstrate that elevated glucose alone induces cardiac defects in zebrafish embryos by altering the expression pattern of tbx5 (show TBX5 ELISA Kits), tbx20, and has2 (show HAS2 ELISA Kits) in the heart

  4. embryos lacking hrT function have dysmorphic hearts and an absence of blood circulation

  5. redundant activities of Nkx2.5 and Nkx2.7 are required for cardiac morphogenesis (show XIRP1 ELISA Kits), but Nkx2.7 plays a more critical function, regulating the expressions of tbx5 (show TBX5 ELISA Kits) and tbx20 through the maturation stage

Xenopus laevis T-Box 20 (TBX20) interaction partners

  1. we show that TBX5 (show TBX5 ELISA Kits) and TBX20 can physically interact and map the interaction domains, and we show a cellular interaction for the two proteins in cardiac development

Human T-Box 20 (TBX20) interaction partners

  1. The current study associated TBX20 haploinefficiency with isolated Dilated cardiomyopathy (DCM), and expanded upon the mutational spectrum of TBX20 associated with DCM and congenital heart disease (CHD (show CHDH ELISA Kits)), which provides novel insight into the molecular mechanism of DCM and CHD (show CHDH ELISA Kits), suggesting potential implications for early personalized treatment of these diseases.

  2. Silencing of TBX20 in rat myocardial and human embryonic kidney cells significantly inhibited cell proliferation, induced cell apoptosis and led to G2/M cell cycle arrest.

  3. rs3999950 may be associated with congenital heart disease, and TBX20 may predispose children to the defect.

  4. Among the 8 SNPs identified, 6 are in strong linkage disequilibrium and the minor alleles are associated with lower CHD (show CHDH ELISA Kits) risk. The minor alleles have lower transcriptional activity than major alleles in both human heart tissues and three cell lines. TBX20 minor alleles may exhibit higher binding affinity with certain transcription repressors.

  5. Cardiac TBX20 expression showed a negative correlation with LVEF and a positive correlation with left ventricular end-systolic volume. No significant difference in TBX20 CNVs and promoter methylation was observed between IDCM patients and control group

  6. The mutation markedly reduced the synergistic activation of TBX20 with NKX2-5 (show NKX2-5 ELISA Kits) or GATA4 (show GATA4 ELISA Kits).

  7. We report three missense mutations (Y309D, T370O, and M395R) within the transcriptional activator domain of human TBX20 that were associated with atrial septal defect

  8. Data showed that the TC genotype of SNP rs3999941 and AC genotype of the new SNP c.657A>C in the TBX20 gene may be risk factors for CHD (show CHDH ELISA Kits).

  9. TBX20 loss-of-function mutation contributes to double outlet right ventricle

  10. A novel TBX20 mutation, c.526G>A (p.D176N), was identified and co-segregated in all affected members in this family of three generations with atrial septal defects.

Mouse (Murine) T-Box 20 (TBX20) interaction partners

  1. Tbx18 (show TBX18 ELISA Kits) does not function redundantly with Tbx2 (show TBX2 ELISA Kits) or Tbx20 in epicardial development.

  2. Cardiomyocyte Tbx20 induced overexpression activates multiple cardiac proliferative pathways, directly represses cell-cycle inhibitory genes p21, Meis1 (show MEIS1 ELISA Kits), and Btg2 (show BTG2 ELISA Kits), promotes adult CM proliferation; and preserves cardiac performance after MI.

  3. TLE1/TLE3-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.

  4. The effects of Tbx20 are epistatic to Tbx3 (show TBX3 ELISA Kits) in the heart, but Tbx3 (show TBX3 ELISA Kits) is epistatic to Tbx20 with respect to developmental delay.

  5. Tbx20-mediated increases in cell proliferation, providing evidence for parallel regulatory pathways downstream of BMP/Smad1 (show SMAD1 ELISA Kits)/5/8 signaling in promoting cardiomyocyte proliferation after birth

  6. Tbx20 is expressed in the developing endocardial cushions and valves throughout heart development. Ablation of Tbx20 in endocardial cells causes severe valve elongation defects and impaired cardiac function.

  7. a dual role for TBX20 as both a transcriptional activator and a repressor, and that each of these functions regulates genes with very specialized and distinct molecular roles

  8. Data show distinct functions for Tbx20 in regulation of cardiomyocyte lineage maturation and cell proliferation at embryonic and fetal stages of heart development.

  9. Genome-wide ChIP analysis of Tbx20-binding regions in the adult heart revealed that many of these genes were direct downstream targets of Tbx20 and uncovered a previously undescribed DNA-binding site for Tbx20.

  10. mice lacking Tbx20 in the atrioventricular canal myocardium fail to form the atrioventricular canal constriction, and the endocardial epithelial-mesenchymal transition (EMT (show ITK ELISA Kits)) is severely perturbed.

TBX20 Antigen Profile

Antigen Summary

This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with T-Box 20 (TBX20) ELISA Kits

  • T-box 20 (TBX20) antibody
  • T-box 20 (tbx20) antibody
  • T-box 20 (LOC100225521) antibody
  • Tbx20-like homeobox protein (tbx20) antibody
  • T-box 20 (Tbx20) antibody
  • T-box transcription factor TBX20-like (TBX20) antibody
  • 9430010M06Rik antibody
  • AL022859 antibody
  • ASD4 antibody
  • cb826 antibody
  • hrt antibody
  • Tbx12 antibody
  • tbx20 antibody
  • tbx20-A antibody
  • XTBX20 antibody
  • ZF-TBX20 antibody

Protein level used designations for T-Box 20 (TBX20) ELISA Kits

T-box 20 , T-box transcription factor 20 , Tbx20-like homeobox protein , H15-related T-box transcription factor hrT , T-box protein 20 , T-box transcription factor TBX20 , cTbx20

GENE ID SPECIES
467053 Pan troglodytes
619590 Xenopus (Silurana) tropicalis
100070390 Equus caballus
100225521 Taeniopygia guttata
100303555 Saccoglossus kowalevskii
57936 Danio rerio
378656 Xenopus laevis
373943 Gallus gallus
57057 Homo sapiens
539419 Bos taurus
57246 Mus musculus
315497 Rattus norvegicus
482396 Canis lupus familiaris
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