anti-T-Complex Protein 1 (TCP1) Antibodies

TCP1 encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. Additionally we are shipping T-Complex Protein 1 Proteins (7) and T-Complex Protein 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TCP1 21454 P11983
TCP1 8626 Q9H3D4
TCP1 246334 Q9JJP6
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Top anti-T-Complex Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 117 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat heart labeled with Rabbit Anti P63 protein/P51A Polyclonal Antibody, Unconjugated (ABIN672336) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated ChIP, ICC, IF, WB p63 antibody (pAb) tested by ChIP. Chromatin IP was performed on chromatin from HaCaT cells. PCR primers were used to amplify a region of the FXDR gene promoter. Lane 1: negative control IgG. Lane 2: p63 antibody. Lane 3: Input DNA control. p63 antibody (pAb) tested by immunofluorescence. HaCaT cells stained with p63 antibody (pAb) (1:500 dilution). 100 μL Log in to see 1 to 2 Days
$495.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from LOVO cells treated with nocodazole 1ug/ml 18h, A549 cells treated with nocodazole 1ug/ml 18h and HepG2 cells treated with nocodazole 1ug/ml 18h, using p63 (Phospho-Ser395) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with TNF 2500U/ML 30', using p63 (Phospho-Ser455) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using p63 (Phospho-Ser455) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Phospho-p63 (S455) Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Western Blot (WB) analysis of HeLa, K562, MCF7, PC-3 cells using p63 Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from COS7 cells, using p63 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using p63 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using p63 , antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using p63, antibody at 1:100 dilution. WB Image p63 antibody [N2C1], Internal detects TP63 protein by Western blot analysis. A. 50 µg rat brain lysate/extract 7.5 % SDS-PAGE p63 antibody [N2C1], Internal , dilution: 1:500 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB 50 μL Log in to see 10 to 12 Days
$135.88
Details

TCP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-T-Complex Protein 1 Antibodies

  1. Human Polyclonal TCP1 Primary Antibody for IHC, WB - ABIN2666194 : Bénard, Douc-Rasy, Ahomadegbe: TP53 family members and human cancers. in Human mutation 2003 (PubMed)
    Show all 6 references for 2666194

  2. Human Polyclonal TCP1 Primary Antibody for IF (p), IHC (p) - ABIN672336 : Yang, Xie, Shu, Liu, Chen, Ruan, Qi: An improved method for the isolation and culture of rat epidermal stem cells. in International journal of clinical and experimental pathology 2013 (PubMed)
    Show all 2 references for 672336

  3. Human Polyclonal TCP1 Primary Antibody for ChIP, ICC - ABIN2668832 : Rhie, Hazelett, Coetzee, Yan, Noushmehr, Coetzee: Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells. in BMC genomics 2014 (PubMed)

More Antibodies against T-Complex Protein 1 Interaction Partners

Mouse (Murine) T-Complex Protein 1 (TCP1) interaction partners

  1. this study shows that CCTalpha (show PCYT1A Antibodies) is required for antigen-specific, germinal center-derived memory B cells

  2. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (show P2RX7 Antibodies) (P2X7R (show P2RX7 Antibodies)) and plays a role in lymphoid neoplasm metastasis.

  3. The data presented here reveal an additional level of interplay between CCT (show FLVCR2 Antibodies) and actin mediated via gelsolin (show GSN Antibodies), suggesting that CCT (show FLVCR2 Antibodies) may influence processes depending on gelsolin (show GSN Antibodies) activity, such as cell motility.

  4. Host CCTalpha (show PCYT1A Antibodies) is required for efficient transcription and replication of rabies virus.

  5. Our data provide new evidence indicating the essential role of the chaperonin CCT in the biogenesis of vertebrate photoreceptor sensory cilia

  6. Results suggest that chaperonin containing t-complex protein 1 (CCT) is required for efficient delivery of enzymatically active toxin to the cytosol and are consistent with a direct role for CCT in translocation of LF through the protective antigen pore.

  7. Normal CCT function is ultimately required for the morphogenesis and survival of sensory neurons of the retina.

  8. TRiC (show MARVELD2 Antibodies)-peptide complexes of the heat shock protein 60 (show HSPD1 Antibodies) family are efficient vehicles of cross-presentation in assays in vitro and in mice in vivo; immunization with TRiC (show MARVELD2 Antibodies) purified from a tumor elicits specific protection against a challenge with that tumor.

  9. downregulated expression in T cells following treatment with bis (show BAG3 Antibodies)(tri (show VANGL2 Antibodies)-n-butylin)oxide (TBTO), an immunotoxic organotin

  10. cellular distribution of CCT during spermatogenesis; in the cytoplasm,it associates to the microtubule organizing center and the manchette; in the nucleus, it concentrates at highly condensed chromatin regions

Human T-Complex Protein 1 (TCP1) interaction partners

  1. p63 (show RPE65 Antibodies) is a master regulator in epidermal biology and regulates glycolysis sugar taste in the epidermis.

  2. Anaplastic large cell lymphomas without TP63 (show TP63 Antibodies) rearrangements may express TAp63 isoforms of p63 (show RPE65 Antibodies) and this expression is associated with extra copies of TP63 (show TP63 Antibodies), probably due to widespread genomic copy number abnormalities rather than focal gains.

  3. Up-regulation of transcription factor DeltaNp63 led to the decline of miR (show MLXIP Antibodies)-181a expression, resulting in an overexpression of the antiaging protein Sirt1 (show SIRT1 Antibodies), in CD4 (show CD4 Antibodies)(+) T cells from HCV-infected individuals. Either reconstituting miR (show MLXIP Antibodies)-181a or silencing DeltaNp63 or Sirt1 (show SIRT1 Antibodies) expression in CD4 (show CD4 Antibodies)(+) T cells led to accelerated T cell senescence.

  4. Knock-down of WWP1 (show WWP1 Antibodies) abrogates DNA damage-induced down-regulation of DeltaNp63alphaand partially rescues cell apoptosis

  5. The reduction of tumor protein p63 (show TP63 Antibodies) and tumor protein p73 (show TP73 Antibodies) isoforms, rather than alteration of DeltaN isoform expression, exerted a significant functional repercussion on cell death and proliferation in hepatitis B virus -expressing HepB cells.

  6. TGF-beta1 (show TGFB1 Antibodies) increased OSCC cell proliferation by upregulating the expression of DeltaNp63 and c-Myc (show MYC Antibodies) oncogenes. Although the basal OSCC cell proliferation is sustained by activating DeltaNp63, increased induction of c-Myc (show MYC Antibodies) causes unregulated OSCC cell proliferation.

  7. Results suggest that TP63 (show TP63 Antibodies) rs7631358 G > A and CSF1R (show CSF1R Antibodies) rs10079250 A > G may affect the risk and prognosis of lung cancer in never-smoking females.

  8. The findings demonstrate that miR (show MLXIP Antibodies)-203a plays an essential role in keratinocyte proliferation and differentiation caused by extracellular calcium by targeting the SNAI2 (show SNAI2 Antibodies) and DeltaNp63 genes.

  9. Immunohistochemical detection of thyroid transcription factor 1 (show NKX2-1 Antibodies), Napsin A (show NAPSA Antibodies), and P40 (show IL9 Antibodies) fragment of TP63 (show TP63 Antibodies) can be used in the subclassification of non-small cell lung carcinomas.

  10. CK5 (show KRT5 Antibodies) and p40 (show IL9 Antibodies) are good diagnostic markers for squamous cell carcinoma and superior to p63 (show RPE65 Antibodies)

T-Complex Protein 1 (TCP1) Antigen Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with TCP1

  • t-complex protein 1 (Tcp1) antibody
  • tumor protein p63 (TP63) antibody
  • tumor protein p63 (Tp63) antibody
  • AI528772 antibody
  • AIS antibody
  • B(p51A) antibody
  • B(p51B) antibody
  • c-cpn antibody
  • CCT antibody
  • Cct1 antibody
  • Ccta antibody
  • EEC3 antibody
  • Ket antibody
  • LMS antibody
  • NBP antibody
  • OFC8 antibody
  • p40 antibody
  • p51 antibody
  • p53CP antibody
  • p63 antibody
  • p73H antibody
  • P73l antibody
  • RHS antibody
  • SHFM4 antibody
  • Tcp-1 antibody
  • TP53CP antibody
  • TP53L antibody
  • Tp63 antibody
  • Tp73l antibody
  • TRic antibody
  • Trp63 antibody

Protein level used designations for TCP1

CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , transformation-related protein 63 , tumor protein 63 , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa

GENE ID SPECIES
21454 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
Selected quality suppliers for anti-T-Complex Protein 1 (TCP1) Antibodies
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