T-Complex Protein 1 Proteins (TCP1)

TCP1 encodes a member of the p53 family of transcription factors. Additionally we are shipping T-Complex Protein 1 Antibodies (117) and T-Complex Protein 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TCP1 21454 P11983
TCP1 8626 Q9H3D4
TCP1 246334 Q9JJP6
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Top T-Complex Protein 1 Proteins at antibodies-online.com

Showing 4 out of 7 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 11 Days
HOST_Baculovirus infected Insect Cells Human GST tag 50 μg Log in to see 10 to 12 Days
Human Un-conjugated 5 μg Log in to see 6 to 8 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated 5 applications Log in to see 1 to 2 Days

TCP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
Human ,
Rat (Rattus)

More Proteins for T-Complex Protein 1 (TCP1) Interaction Partners

Mouse (Murine) T-Complex Protein 1 (TCP1) interaction partners

  1. this study shows that CCTalpha (show PCYT1A Proteins) is required for antigen-specific, germinal center-derived memory B cells

  2. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (show P2RX7 Proteins) (P2X7R (show P2RX7 Proteins)) and plays a role in lymphoid neoplasm metastasis.

  3. The data presented here reveal an additional level of interplay between CCT (show FLVCR2 Proteins) and actin mediated via gelsolin (show GSN Proteins), suggesting that CCT (show FLVCR2 Proteins) may influence processes depending on gelsolin (show GSN Proteins) activity, such as cell motility.

  4. Host CCTalpha (show PCYT1A Proteins) is required for efficient transcription and replication of rabies virus.

  5. Our data provide new evidence indicating the essential role of the chaperonin CCT in the biogenesis of vertebrate photoreceptor sensory cilia

  6. Results suggest that chaperonin containing t-complex protein 1 (CCT) is required for efficient delivery of enzymatically active toxin to the cytosol and are consistent with a direct role for CCT in translocation of LF through the protective antigen pore.

  7. Normal CCT function is ultimately required for the morphogenesis and survival of sensory neurons of the retina.

  8. TRiC (show MARVELD2 Proteins)-peptide complexes of the heat shock protein 60 (show HSPD1 Proteins) family are efficient vehicles of cross-presentation in assays in vitro and in mice in vivo; immunization with TRiC (show MARVELD2 Proteins) purified from a tumor elicits specific protection against a challenge with that tumor.

  9. downregulated expression in T cells following treatment with bis (show BAG3 Proteins)(tri (show VANGL2 Proteins)-n-butylin)oxide (TBTO), an immunotoxic organotin

  10. cellular distribution of CCT during spermatogenesis; in the cytoplasm,it associates to the microtubule organizing center and the manchette; in the nucleus, it concentrates at highly condensed chromatin regions

Human T-Complex Protein 1 (TCP1) interaction partners

  1. a major effect of p63 (show RPE65 Proteins) is regulation of cell adhesion, a process important in metastasis and invasion of tumour cells. That this effect is not seen in mesenchymal-type TNBC cells suggests lineage-dependent functions, mirroring the expression of Np63alpha in primary human breast cancers.

  2. p63 (show RPE65 Proteins) is a master regulator in epidermal biology and regulates glycolysis sugar taste in the epidermis.

  3. Anaplastic large cell lymphomas without TP63 (show TP63 Proteins) rearrangements may express TAp63 isoforms of p63 (show RPE65 Proteins) and this expression is associated with extra copies of TP63 (show TP63 Proteins), probably due to widespread genomic copy number abnormalities rather than focal gains.

  4. Up-regulation of transcription factor DeltaNp63 led to the decline of miR (show MLXIP Proteins)-181a expression, resulting in an overexpression of the antiaging protein Sirt1 (show SIRT1 Proteins), in CD4 (show CD4 Proteins)(+) T cells from HCV-infected individuals. Either reconstituting miR (show MLXIP Proteins)-181a or silencing DeltaNp63 or Sirt1 (show SIRT1 Proteins) expression in CD4 (show CD4 Proteins)(+) T cells led to accelerated T cell senescence.

  5. Knock-down of WWP1 (show WWP1 Proteins) abrogates DNA damage-induced down-regulation of DeltaNp63alphaand partially rescues cell apoptosis

  6. The reduction of tumor protein p63 (show TP63 Proteins) and tumor protein p73 (show TP73 Proteins) isoforms, rather than alteration of DeltaN isoform expression, exerted a significant functional repercussion on cell death and proliferation in hepatitis B virus -expressing HepB cells.

  7. TGF-beta1 (show TGFB1 Proteins) increased OSCC cell proliferation by upregulating the expression of DeltaNp63 and c-Myc (show MYC Proteins) oncogenes. Although the basal OSCC cell proliferation is sustained by activating DeltaNp63, increased induction of c-Myc (show MYC Proteins) causes unregulated OSCC cell proliferation.

  8. Results suggest that TP63 (show TP63 Proteins) rs7631358 G > A and CSF1R (show CSF1R Proteins) rs10079250 A > G may affect the risk and prognosis of lung cancer in never-smoking females.

  9. The findings demonstrate that miR (show MLXIP Proteins)-203a plays an essential role in keratinocyte proliferation and differentiation caused by extracellular calcium by targeting the SNAI2 (show SNAI2 Proteins) and DeltaNp63 genes.

  10. Immunohistochemical detection of thyroid transcription factor 1 (show NKX2-1 Proteins), Napsin A (show NAPSA Proteins), and P40 (show IL9 Proteins) fragment of TP63 (show TP63 Proteins) can be used in the subclassification of non-small cell lung carcinomas.

T-Complex Protein 1 (TCP1) Protein Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with T-Complex Protein 1 Proteins (TCP1)

  • t-complex protein 1 (Tcp1)
  • tumor protein p63 (TP63)
  • tumor protein p63 (Tp63)
  • AI528772 protein
  • AIS protein
  • B(p51A) protein
  • B(p51B) protein
  • c-cpn protein
  • CCT protein
  • Cct1 protein
  • Ccta protein
  • EEC3 protein
  • Ket protein
  • LMS protein
  • NBP protein
  • OFC8 protein
  • p40 protein
  • p51 protein
  • p53CP protein
  • p63 protein
  • p73H protein
  • P73l protein
  • RHS protein
  • SHFM4 protein
  • Tcp-1 protein
  • TP53CP protein
  • TP53L protein
  • Tp63 protein
  • Tp73l protein
  • TRic protein
  • Trp63 protein

Protein level used designations for T-Complex Protein 1 Proteins (TCP1)

CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , transformation-related protein 63 , tumor protein 63 , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa

21454 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
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