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T-Complex Protein 1 Proteins (TCP1)

TCP1 encodes a member of the p53 family of transcription factors. Additionally we are shipping T-Complex Protein 1 Antibodies (117) and T-Complex Protein 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TCP1 21454 P11983
TCP1 8626 Q9H3D4
TCP1 246334 Q9JJP6
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Top T-Complex Protein 1 Proteins at

Showing 4 out of 7 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 11 Days
HOST_Baculovirus infected Insect Cells Human GST tag 50 μg Log in to see 10 to 12 Days
Human Un-conjugated 5 μg Log in to see 6 to 8 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated 5 applications Log in to see 1 to 2 Days

TCP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
Human ,
Rat (Rattus)

More Proteins for T-Complex Protein 1 (TCP1) Interaction Partners

Mouse (Murine) T-Complex Protein 1 (TCP1) interaction partners

  1. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (show P2RX7 Proteins) (P2X7R (show P2RX7 Proteins)) and plays a role in lymphoid neoplasm metastasis.

  2. The data presented here reveal an additional level of interplay between CCT (show FLVCR2 Proteins) and actin mediated via gelsolin (show GSN Proteins), suggesting that CCT (show FLVCR2 Proteins) may influence processes depending on gelsolin (show GSN Proteins) activity, such as cell motility.

  3. Host CCTalpha (show PCYT1A Proteins) is required for efficient transcription and replication of rabies virus.

  4. Our data provide new evidence indicating the essential role of the chaperonin CCT in the biogenesis of vertebrate photoreceptor sensory cilia

  5. Results suggest that chaperonin containing t-complex protein 1 (CCT) is required for efficient delivery of enzymatically active toxin to the cytosol and are consistent with a direct role for CCT in translocation of LF through the protective antigen pore.

  6. Normal CCT function is ultimately required for the morphogenesis and survival of sensory neurons of the retina.

  7. TRiC (show MARVELD2 Proteins)-peptide complexes of the heat shock protein 60 (show HSPD1 Proteins) family are efficient vehicles of cross-presentation in assays in vitro and in mice in vivo; immunization with TRiC (show MARVELD2 Proteins) purified from a tumor elicits specific protection against a challenge with that tumor.

  8. downregulated expression in T cells following treatment with bis (show BAG3 Proteins)(tri (show VANGL2 Proteins)-n-butylin)oxide (TBTO), an immunotoxic organotin

  9. cellular distribution of CCT during spermatogenesis; in the cytoplasm,it associates to the microtubule organizing center and the manchette; in the nucleus, it concentrates at highly condensed chromatin regions

Human T-Complex Protein 1 (TCP1) interaction partners

  1. In diffuse large B-cell lymphoma, PD-1 (show PDCD1 Proteins) was expressed in tumor-infiltrating lymphocytes of 39.5% patients. PD-L1 (show CD274 Proteins) was expressed in tumor cells of 26.3% patients, and TP63 (show TP63 Proteins) was in tumor cells of 31.6% cases. PD-1 (show PDCD1 Proteins) expression was associated with the patients' gender and B symptoms. PD-1 (show PDCD1 Proteins) in tumor-infiltrating lymphocytes was related to prolonged overall survival, but PD-L1 (show CD274 Proteins) expression was associated with worse clinical outcome.

  2. Downregulation of TP63 (show TP63 Proteins) is associated with colorectal cancer.

  3. These results suggest that whereas GATA-3 and uroplakin II may be most useful in the diagnosis of urothelial carcinoma metastasis, p40 may be additionally suited as a prognostic marker.

  4. TP63 (show TP63 Proteins) gene mutation is involved in the familial ADULT syndrome diagnosed in a family.

  5. A large number of giant cell tumors of bone (96.8%) are positive for p63 (show RPE65 Proteins), which is considerably more than any other giant cell-rich lesion.

  6. The expression of CK5 (show KRT5 Proteins)/6 and of P63 (show RPE65 Proteins) suggests a squamous differentiation including in the basaloid thyroid lymphoepithelial complexes

  7. DeltaNp63alpha is a vital epithelial-mesenchymal transition repressor in cervical squamous cell carcinoma cells. SCC (show CYP11A1 Proteins) patients with low DeltaNp63alpha expression and high EMT (show ITK Proteins) level show more frequent metastasis and recurrence as well as reduced overall survival. The miR (show MLXIP Proteins)-205/ZEB1 axis is involved in the inhibition effect of DeltaNp63alpha on EMT (show ITK Proteins).

  8. Immunocytochemistry using this antibody cocktail comprises five antibodies recognising p63 (show RPE65 Proteins), and cytokeratins ( 7, 18, 5 and 14) showed good sensitivity and specificity for diagnosing breast cancers. Thus, this method is useful for mammary cytology using FNA

  9. HCC1806 cells endogenously express p63 (show RPE65 Proteins), mainly as the DeltaNp63alpha isoform. Endogenous p63 (show RPE65 Proteins) is required to suppress the expression of luminal markers and maintain the basal epithelial phenotype, but p63 (show RPE65 Proteins) loss is insufficient to induce full luminal-type differentiation. p63 (show RPE65 Proteins) exerts multiple pro-oncogenic effects on cell differentiation, proliferation and adhesion in basal-like breast cancers.

  10. The findings suggest that miR (show MLXIP Proteins)-203 is a tumor suppressor that plays an important role in inhibiting the occurrence of Kazakh esophageal squamous cell carcinoma in China via regulating the expression of p63 (show RPE65 Proteins).

T-Complex Protein 1 (TCP1) Protein Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with T-Complex Protein 1 Proteins (TCP1)

  • t-complex protein 1 (Tcp1)
  • tumor protein p63 (TP63)
  • tumor protein p63 (Tp63)
  • AI528772 protein
  • AIS protein
  • B(p51A) protein
  • B(p51B) protein
  • c-cpn protein
  • CCT protein
  • Cct1 protein
  • Ccta protein
  • EEC3 protein
  • Ket protein
  • LMS protein
  • NBP protein
  • OFC8 protein
  • p40 protein
  • p51 protein
  • p53CP protein
  • p63 protein
  • p73H protein
  • P73l protein
  • RHS protein
  • SHFM4 protein
  • Tcp-1 protein
  • TP53CP protein
  • TP53L protein
  • Tp63 protein
  • Tp73l protein
  • TRic protein
  • Trp63 protein

Protein level used designations for T-Complex Protein 1 Proteins (TCP1)

CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , transformation-related protein 63 , tumor protein 63 , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa

21454 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
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