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TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) Proteins (TELO2)

TELO2 encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. Additionally we are shipping TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat TELO2 TELO2 302986  
TELO2 71718 Q9DC40
TELO2 9894 Q9Y4R8
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Top TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TELO2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) Interaction Partners

Mouse (Murine) TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) interaction partners

  1. IP7, formed by IP6K2 (show IP6K2 Proteins), binds CK2 (show CSNK2A1 Proteins) to enhance its phosphorylation of the Tti1/Tel2 complex, thereby stabilizing DNA-PKcs (show PRKDC Proteins) and ATM (show ATM Proteins). This process stimulates p53 (show TP53 Proteins) phosphorylation at serine 15 to activate the cell death program.

  2. The CK2 phospho-dependent interaction between TEL2 and the R2TP complex affects phosphatidylinositol 3-kinase-related kinase functions and is essential for mTOR and SMG1 stability in vivo.

  3. Identify Tel2 as a highly conserved regulator of the stability of PI3K-related protein kinases.

Human TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) interaction partners

  1. IP7, formed by IP6K2 (show IP6K2 Proteins), binds CK2 (show CSNK2A1 Proteins) to enhance its phosphorylation of the Tti1/Tel2 complex, thereby stabilizing DNA-PKcs (show PRKDC Proteins) and ATM (show ATM Proteins). This process stimulates p53 (show TP53 Proteins) phosphorylation at serine 15 to activate the cell death program.

  2. The SAM (show TTN Proteins) domain of human TEL2 can inhibit the transcriptional activities of ETS1 (show ETS1 Proteins)/2 and TEL1 (show ATM Proteins).

  3. Data show that that knockdown of either Tti1 or Tel2 causes disassembly of mTORC1 and mTORC2 (show CRTC2 Proteins).

  4. The CK2 phospho-dependent interaction between TEL2 and the R2TP complex affects phosphatidylinositol 3-kinase-related kinase functions and is essential for mTOR and SMG1 stability in vivo.

  5. TTI1 and TTI2 (show TTI2 Proteins) exist in multiple complexes, including a 2-MDa complex with TEL2 (telomere maintenance 2), called the Triple T complex, and phosphoinositide-3-kinase-related protein (show MYLK Proteins) kinases (PIKKs) such as ataxia telangiectasia-mutated (ATM (show ATM Proteins)).

TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) Protein Profile

Protein Summary

This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.

Gene names and symbols associated with TELO2

  • TEL2, telomere maintenance 2, homolog (S. cerevisiae) (Telo2)
  • telomere maintenance 2 (TELO2)
  • 1200003M09Rik protein
  • AI415602 protein
  • CLK2 protein
  • mKIAA0683 protein
  • RGD1305553 protein
  • TEL2 protein

Protein level used designations for TELO2

telomere length regulation protein TEL2 homolog , TEL2, telomere maintenance 2, homolog , protein clk-2 homolog

GENE ID SPECIES
302986 Rattus norvegicus
71718 Mus musculus
9894 Homo sapiens
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