anti-TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) Antibodies

TELO2 encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. Additionally we are shipping TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TELO2 302986  
TELO2 71718 Q9DC40
TELO2 9894 Q9Y4R8
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Top anti-TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: TELO2 Sample Type: HepG2 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of TELO2 Antibody (C-term) (ABIN651003) in K562 cell line lysates (35 µg/lane). TELO2 (arrow) was detected using the purified polyclonal antibody. TELO2 Antibody (C-term) (ABIN651003) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: TEL2 Antibody  - Immunofluorescent staining of human cell line A-431 shows localization to cytosol. Immunohistochemistry-Paraffin: TEL2 Antibody  - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of TEL2 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of TEL2 expression in A431 (A), Hela (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: TEL2 Antibody  - Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies & cytosol. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ELISA, FACS, IHC, WB   200 μL Log in to see 7 to 9 Days
$793.83
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Biotin FACS, IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit FITC FACS, IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

TELO2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Mouse (Murine)


Human ,


, , , , ,

Top referenced anti-TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) Antibodies

  1. Human Polyclonal TELO2 Primary Antibody for ICC, IF - ABIN4358369 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) Interaction Partners

Mouse (Murine) TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) interaction partners

  1. IP7, formed by IP6K2 (show IP6K2 Antibodies), binds CK2 (show CSNK2A1 Antibodies) to enhance its phosphorylation of the Tti1 (show TTI1 Antibodies)/Tel2 complex, thereby stabilizing DNA-PKcs (show PRKDC Antibodies) and ATM (show ATM Antibodies). This process stimulates p53 (show TP53 Antibodies) phosphorylation at serine 15 to activate the cell death program.

  2. The CK2 (show CSNK2A1 Antibodies) phospho-dependent interaction between TEL2 and the R2TP complex affects phosphatidylinositol 3-kinase-related kinase (show SMG1 Antibodies) functions and is essential for mTOR (show FRAP1 Antibodies) and SMG1 (show SMG1 Antibodies) stability in vivo.

  3. Identify Tel2 as a highly conserved regulator of the stability of PI3K-related protein kinases.

Human TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) interaction partners

  1. TELO2 missense variants result in loss of function, perturb TTT complex stability, and cause an autosomal-recessive syndromic form of Intellectual Disability Disorder.

  2. IP7, formed by IP6K2 (show IP6K2 Antibodies), binds CK2 (show CSNK2A1 Antibodies) to enhance its phosphorylation of the Tti1 (show TTI1 Antibodies)/Tel2 complex, thereby stabilizing DNA-PKcs (show PRKDC Antibodies) and ATM (show ATM Antibodies). This process stimulates p53 (show TP53 Antibodies) phosphorylation at serine 15 to activate the cell death program.

  3. The SAM (show TTN Antibodies) domain of human TEL2 can inhibit the transcriptional activities of ETS1 (show ETS1 Antibodies)/2 and TEL1 (show ATM Antibodies).

  4. Data show that that knockdown of either Tti1 (show TTI1 Antibodies) or Tel2 causes disassembly of mTORC1 and mTORC2 (show CRTC2 Antibodies).

  5. The CK2 (show CSNK2A1 Antibodies) phospho-dependent interaction between TEL2 and the R2TP complex affects phosphatidylinositol 3-kinase-related kinase (show SMG1 Antibodies) functions and is essential for mTOR (show FRAP1 Antibodies) and SMG1 (show SMG1 Antibodies) stability in vivo.

  6. TTI1 (show TTI1 Antibodies) and TTI2 (show TTI2 Antibodies) exist in multiple complexes, including a 2-MDa complex with TEL2 (telomere maintenance 2), called the Triple T complex, and phosphoinositide-3-kinase-related protein (show MYLK Antibodies) kinases (PIKKs) such as ataxia telangiectasia-mutated (ATM (show ATM Antibodies)).

TEL2, Telomere Maintenance 2, Homolog (S. Cerevisiae) (TELO2) Antigen Profile

Protein Summary

This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.

Gene names and symbols associated with TELO2

  • TEL2, telomere maintenance 2, homolog (S. cerevisiae) (Telo2) antibody
  • telomere maintenance 2 (TELO2) antibody
  • 1200003M09Rik antibody
  • AI415602 antibody
  • CLK2 antibody
  • mKIAA0683 antibody
  • RGD1305553 antibody
  • TEL2 antibody

Protein level used designations for TELO2

telomere length regulation protein TEL2 homolog , TEL2, telomere maintenance 2, homolog , protein clk-2 homolog

GENE ID SPECIES
302986 Rattus norvegicus
71718 Mus musculus
9894 Homo sapiens
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