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anti-TELO2 Interacting Protein 1 (TTI1) Antibodies

Regulator of the DNA damage response (DDR). Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TTI1 9675 O43156
Anti-Mouse TTI1 TTI1 75425 Q91V83
Anti-Rat TTI1 TTI1 499935  
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Top anti-TELO2 Interacting Protein 1 Antibodies at antibodies-online.com

Showing 3 out of 11 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB 200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA 200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IF, ELISA, WB 200 μL Log in to see 8 to 9 Days
$588.50
Details

TTI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,

More Antibodies against TELO2 Interacting Protein 1 Interaction Partners

Human TELO2 Interacting Protein 1 (TTI1) interaction partners

  1. IP7, formed by IP6K2 (show IP6K2 Antibodies), binds CK2 (show CSNK2A1 Antibodies) to enhance its phosphorylation of the Tti1/Tel2 (show TELO2 Antibodies) complex, thereby stabilizing DNA-PKcs (show PRKDC Antibodies) and ATM (show ATM Antibodies). This process stimulates p53 (show TP53 Antibodies) phosphorylation at serine 15 to activate the cell death program.

  2. TTI1 and TTI2 (show TTI2 Antibodies) protect cells from spontaneous DNA damage, and are required for the establishment of the intra-S and G2/M checkpoin

  3. Data show that that knockdown of either Tti1 or Tel2 (show TELO2 Antibodies) causes disassembly of mTORC1 and mTORC2 (show CRTC2 Antibodies).

Mouse (Murine) TELO2 Interacting Protein 1 (TTI1) interaction partners

  1. IP7, formed by IP6K2 (show IP6K2 Antibodies), binds CK2 (show CSNK2A1 Antibodies) to enhance its phosphorylation of the Tti1/Tel2 (show TELO2 Antibodies) complex, thereby stabilizing DNA-PKcs (show PRKDC Antibodies) and ATM (show ATM Antibodies). This process stimulates p53 (show TP53 Antibodies) phosphorylation at serine 15 to activate the cell death program.

TELO2 Interacting Protein 1 (TTI1) Antigen Profile

Protein Summary

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Gene names and symbols associated with TTI1

  • TELO2 interacting protein 1 (TTI1) antibody
  • TELO2 interacting protein 1 (Tti1) antibody
  • 2610036D13Rik antibody
  • AI449463 antibody
  • KIAA0406 antibody
  • RGD1562582 antibody
  • smg-10 antibody

Protein level used designations for TTI1

TEL2-interacting protein 1 homolog , TELO2-interacting protein 1 homolog , Tel two interacting protein 1 , Tel2 interacting protein 1 homolog , smg-10 homolog, nonsense mediated mRNA decay factor

GENE ID SPECIES
9675 Homo sapiens
477225 Canis lupus familiaris
75425 Mus musculus
499935 Rattus norvegicus
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