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TGFB-Induced Factor Homeobox 2 Proteins (TGIF2)

The protein encoded by TGIF2 is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. Additionally we are shipping TGIF2 Antibodies (86) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TGIF2 60436 Q9GZN2
TGIF2 228839 Q8C0Y1
Rat TGIF2 TGIF2 681373  
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Top TGIF2 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TGIF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for TGFB-Induced Factor Homeobox 2 (TGIF2) Interaction Partners

Human TGFB-Induced Factor Homeobox 2 (TGIF2) interaction partners

  1. expression of miR (show MLXIP Proteins)-148a was regulated by DNA methylation (show HELLS Proteins) and targeted by TGIF2. Its methylation may be a potential prognostic indicator in skin cancer

  2. miR (show MLXIP Proteins)-34a could inhibit tumor invasion and metastasis in gastric cancer by targeting Tgif2

  3. Corneal fibroblasts demonstrate the expression of TGIF1 (show TGIF1 Proteins) and TGIF2 transcription factors. These transcriptional repressors are critical, at least partially, in mediating the antifibrotic effect of vorinostat in the cornea.

  4. Shows that the homologous mouse Tgif2 gene is necessary (show TGIF1 Proteins) for gastrulation.

Mouse (Murine) TGFB-Induced Factor Homeobox 2 (TGIF2) interaction partners

  1. Data show that loss-of-function mutations in both Tgif1 (show TGIF1 Proteins) and Tgif2 result in a failure of gastrulation.

  2. TGIF2 has a wide but well controlled expression pattern during mouse development.

  3. The Tgif2 gene contains a retained intron, within the second coding exon. One splice variant encodes the full length 237 amino acid Tgif2, whereas the shorter form results in the removal of 39 codons from the centre of the coding region.

  4. TGIF2 is the molecular link between dorsoventral patterning of the endoderm and pancreatic specification.

TGIF2 Protein Profile

Protein Summary

The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene.

Gene names and symbols associated with TGIF2

  • TGFB-induced factor homeobox 2 (tgif2)
  • TGFB-induced factor homeobox 2 (TGIF2)
  • TGFB-induced factor homeobox 2 (Tgif2)
  • TGFB-induced factor homeobox 2, pseudogene 1 (Tgif2-ps1)
  • 4921501K24 protein
  • 5730599O09Rik protein
  • C80753 protein
  • C81206 protein
  • MGC81646 protein
  • RGD1561562 protein
  • RGD1561975 protein
  • Tgif2 protein
  • Tgif2l2 protein
  • xtgif2 protein

Protein level used designations for TGIF2

TGFB-induced factor homeobox 2 , 5'-TG-3' interacting factor 2 , TGF(beta)-induced transcription factor 2 , TGF-beta-induced transcription factor 2 , TGFB-induced factor 2 (TALE family homeobox) , homeobox protein TGIF2 , transcription growth factor-beta-induced factor 2 , 5'-TG-3'-interacting factor 2 , TALE family homeobox , TGFB-induced factor 2

GENE ID SPECIES
447461 Xenopus laevis
735483 Pan troglodytes
100127190 Xenopus (Silurana) tropicalis
60436 Homo sapiens
485857 Canis lupus familiaris
228839 Mus musculus
681373 Rattus norvegicus
Selected quality suppliers for TGIF2 Proteins (TGIF2)
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