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THO Complex 1 (THOC1) ELISA Kits

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010].. Additionally we are shipping THOC1 Antibodies (82) and THOC1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human THOC1 THOC1 9984 Q96FV9
Anti-Mouse THOC1 THOC1 225160 Q8R3N6
Anti-Rat THOC1 THOC1 291797  
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More ELISA Kits for THOC1 Interaction Partners

Human THO Complex 1 (THOC1) interaction partners

  1. Colorectal cancer patients with high levels of Thoc1 expression had poorer overall-survival and disease-free survival, whereas those with lower levels of Thoc1 expression survived longer.

  2. In humans, high THOC1 protein expression associates with prostate cancer aggressiveness and recurrence. Thus, THOC1 protein is a molecular marker that may improve the identification of aggressive prostate cancers, potentially reducing overtreatment.

  3. Thoc1 inhibits cell growth via induction of cell cycle arrest and apoptosis in lung cancer cells.

  4. This suggests NEDD4-1 (show NEDD4 ELISA Kits) functions in conjunction with other post-translational mechanisms to regulate Thoc1 protein and THO (show THOC2 ELISA Kits) activity.

  5. overexpression of hTREX84 is associated with cancer cell transformation, proliferation and may be regulated by RelA/p65 (show NFkBP65 ELISA Kits)

  6. We show that human THO (show THOC2 ELISA Kits) depletion impairs transcription elongation and mRNA export and increases instability associated with DNA breaks, leading to hyper-recombination and gammaH2AX (show H2AFX ELISA Kits) and 53BP1 (show TP53BP1 ELISA Kits) foci accumulation

  7. A differential connection between tumorogenesis and the expression levels of human THO (show THOC2 ELISA Kits) and ALY (show THOC4 ELISA Kits).

  8. hHpr1/p84/Thoc1 regulates transcriptional elongation and may participate in a protein complex functionally analogous to yeast TREX, physically linking elongating RNA polymerase II with RNA processing factors

  9. Thoc1 may be important for neoplastic transformation

  10. Cells respond to AAV infection by activating two DNA damage signaling cascades. The first activates the p84N5 protein, which in turn activates caspase-6 (show CASP6 ELISA Kits), leading to cell death.

Mouse (Murine) THO Complex 1 (THOC1) interaction partners

  1. granulocyte macrophage progenitors have a cell autonomous requirement for Thoc1 to maintain cell growth and viability

  2. Thoc1 gene deletion prevents prostate cancer progression in mice, but has little effect on normal tissue. Prostate cancer cells deprived of Thoc1 show gene expression defects that compromise cell growth.

  3. Thoc1 loss compromises the proliferation and lineage-generating capacity of small intestinal stem cells, disrupting the supply of differentiated cells in this rapidly renewing tissue.

  4. This suggests NEDD4-1 (show NEDD4 ELISA Kits) functions in conjunction with other post-translational mechanisms to regulate Thoc1 protein and THO (show THOC2 ELISA Kits) activity.

  5. results demonstrate that NO-mediated thoc1 downregulation, via Nrf2, is a key step in the cancer cell apoptosis induced by CCL-34-treated macrophages

  6. THOC5/Fms interacting protein (show THOC5 ELISA Kits) is an essential element in the maintenance of hematopoiesis, and depletion of THOC5/Fms interacting protein (show THOC5 ELISA Kits) causes the down-regulation of THOC1, which may contribute to altered THO (show THOC2 ELISA Kits) complex function and cell death

  7. The generation and phenotypic characterization of mice containing a null allele of the Thoc1 gene is described.

  8. These findings support the notion that Thoc1-mediated RNP (show RNPC3 ELISA Kits) assembly contributes to the coordinated expression of genes necessary for normal differentiation and development in vivo.

THOC1 Antigen Profile

Antigen Summary

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).

Gene names and symbols associated with THO Complex 1 (THOC1) ELISA Kits

  • THO complex 1 (thoc1) antibody
  • THO complex 1 (THOC1) antibody
  • THO complex 1 (Thoc1) antibody
  • THO complex 1 protein (thoc1) antibody
  • 3110002N20Rik antibody
  • AW107452 antibody
  • HPR1 antibody
  • LRRGT00070 antibody
  • MGC114861 antibody
  • NMP-84 antibody
  • P84 antibody
  • P84N5 antibody
  • Tho1 antibody
  • THOC1 antibody

Protein level used designations for THO Complex 1 (THOC1) ELISA Kits

THO complex subunit 1 , THO complex 1 , nuclear matrix protein p84 , THO complex subunit 1-like , THO complex 1 protein , hTREX84 , tho1

GENE ID SPECIES
373077 Danio rerio
398505 Xenopus laevis
421062 Gallus gallus
455324 Pan troglodytes
697954 Macaca mulatta
100051155 Equus caballus
100123388 Nasonia vitripennis
100393939 Callithrix jacchus
100473279 Ailuropoda melanoleuca
100580031 Nomascus leucogenys
100625217 Sus scrofa
733546 Xenopus (Silurana) tropicalis
9984 Homo sapiens
225160 Mus musculus
291797 Rattus norvegicus
490529 Canis lupus familiaris
100138748 Bos taurus
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