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anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) Antibodies

The product encoded by TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. Additionally we are shipping TIA1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIA1 21841 P52912
TIA1 7072 P31483
TIA1 312510  
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Top anti-TIA1 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN190808 (0.1 ug/ml) staining of Jurkat cell lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TIA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated EIA, IHC (p), WB Immunohistochemistry Image: Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE). Western Blot Image: Antibody (0.1 µg/ml) staining of Jurkat cell lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB Anti-TIA1 antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: RAJI Cell Lysate Lane 3: CEM Cell Lysate Lane 4:  Cell Lysate Lane 5: K562 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IHC (fro), IHC (p)   1 mL Log in to see 6 to 8 Days
$445.50
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details

TIA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TIA1 Antibodies

  1. Human Monoclonal TIA1 Primary Antibody for IHC (fro), IHC (p) - ABIN955205 : Francis, Connelly: Rapid single-step method for flow cytometric detection of surface and intracellular antigens using whole blood. in Cytometry 1997 (PubMed)
    Show all 4 references for ABIN955205

  2. Chicken Polyclonal TIA1 Primary Antibody for WB - ABIN2776556 : López de Silanes, Galbán, Martindale, Yang, Mazan-Mamczarz, Indig, Falco, Zhan, Gorospe: Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. in Molecular and cellular biology 2005 (PubMed)

  3. Dog (Canine) Polyclonal TIA1 Primary Antibody for WB - ABIN374795 : Yang, Peng, Murray, Otsuka, Kedersha, Schoenberg: Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1. in Molecular and cellular biology 2006 (PubMed)

More Antibodies against TIA1 Interaction Partners

Mouse (Murine) TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) interaction partners

  1. This study showed that reactive oxygen species such as H2O2 oxidize the cytoplasmic stress granules (SG)-nucleating protein TIA1, thereby inhibiting SG assembly.

  2. Genetic ablation of the stress granule nucleator TIA-1 has a novel major effect on mRNAs encoding lipid homeostasis factors in the brain, similar to the fasting effect.

  3. TIA proteins can function as long-term regulators of the ACTB (show ACTB Antibodies) mRNA metabolism in mouse and human cells.

  4. TIA-1 binds tick-borne encephalitis virus RNA and is recruited to perinuclear sites of viral replication to inhibit viral translation.

  5. Either TIA1 or TIAR (show TIAL1 Antibodies) inactivation broadly alter normal development-associated signalling pathways in murine embryonic fibroblasts.

  6. TIA-1 as a negative regulator of allergen-mediated pulmonary inflammation in vivo.

  7. Data suggest that TIA-1 functions as a translational silencer of cyclooxygenase-2 (COX-2 (show PTGS2 Antibodies)) expression and support the hypothesis that dysregulated RNA-binding of TIA-1 promotes COX-2 (show COX2 Antibodies) expression in neoplasia.

  8. TIA-1 and TTP (show ZFP36 Antibodies) are genetic modifiers of inflammatory arthritis that can alter the spectrum of cells that produce arthritogenic cytokines

  9. TIAR (show TIAL1 Antibodies) regulates the relative expression of TIA-1 isoforms.

  10. TIA-1-induced polysome disassembly is required for enhanced mRNA decay

Human TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) interaction partners

  1. AT1R (show AGTR1 Antibodies) mRNA is regulated by TIA-1 in a ER stress-dependent manner.

  2. This study showed that reactive oxygen species such as H2O2 oxidize the cytoplasmic stress granules (SG)-nucleating protein TIA1, thereby inhibiting SG assembly.

  3. SERPINE1 (show SERPINE1 Antibodies) mRNA dissociates from the translational repressor proteins Ago2 (show EIF2C2 Antibodies) and TIA-1 upon platelet activation

  4. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance.

  5. results suggest that TIA-1 and TIAR (show TIAL1 Antibodies) are two new host factors that interact with 5-UTR (show UTS2R Antibodies) of EV71 genome and positively regulate viral replication

  6. TIA1 inhibition of the exon 8 exclusion led to a decrease in SIRT1 (show SIRT1 Antibodies)-Exon8 mRNA levels.

  7. TIA proteins can function as long-term regulators of the ACTB (show ACTB Antibodies) mRNA metabolism in mouse and human cells.

  8. TIA1-knockdown HeLa cells show an increase in ribosomes and translational machinery components.

  9. Structural insights into the role of binding avidity and the contributions of the TIA-1 RNA recognition motifs for recognition of pyrimidine-rich RNAs.

  10. TIA1 gene expression do not predict prognosis in patients diagnosed with cutaneous T-cell lymphoma.

TIA1 Antigen Profile

Protein Summary

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Gene names and symbols associated with TIA1

  • nucleolysin TIA-1 isoform p40 (PTRG_10065) antibody
  • nucleolysin TIA-1 isoform p40 (PGTG_08590) antibody
  • nucleolysin tia-1 (AaeL_AAEL006710) antibody
  • nucleolysin tia-1 (CpipJ_CPIJ013665) antibody
  • nucleolysin TIA-1 (VDBG_07004) antibody
  • nucleolysin TIA-1 (MGYG_03339) antibody
  • nucleolysin TIA-1 (Tsp_15456) antibody
  • TIA1 cytotoxic granule-associated RNA binding protein (tia1) antibody
  • cytotoxic granule-associated RNA binding protein 1 (Tia1) antibody
  • TIA1 cytotoxic granule-associated RNA binding protein (TIA1) antibody
  • TIA1 cytotoxic granule-associated RNA binding protein (Tia1) antibody
  • 2310050N03Rik antibody
  • AI256674 antibody
  • mTIA-1 antibody
  • tia-1 antibody
  • tia1 antibody
  • TIAL1 antibody
  • TIAR antibody
  • WDM antibody

Protein level used designations for TIA1

nucleolysin TIA-1 isoform p40 , nucleolysin tia-1 , nucleolysin TIA-1 , TIA1 cytotoxic granule-associated RNA binding protein , Nucleolysin TIA-1 , RNA-binding protein TIA-1 , T-cell-restricted intracellular antigen-1 , cytotoxic granule-associated RNA-binding protein 1 , p40-TIA-1 (containing p15-TIA-1) , TIA1 cytotoxic granule-associated RNA binding protein-like 1 , nucleolysin TIAR , cytotoxic granule-associated RNA binding protein 1

GENE ID SPECIES
6348364 Pyrenophora tritici-repentis Pt-1C-BFP
10545120 Puccinia graminis f. sp. tritici CRL 75-36-700-3
5568274 Aedes aegypti
6046587 Culex quinquefasciatus
9527427 Verticillium alfalfae VaMs.102
10031129 Arthroderma gypseum CBS 118893
10897100 Trichinella spiralis
100196522 Salmo salar
21841 Mus musculus
7072 Homo sapiens
771327 Gallus gallus
538533 Bos taurus
312510 Rattus norvegicus
610625 Canis lupus familiaris
447385 Xenopus laevis
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