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TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Proteins (TIAL1)

The protein encoded by TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. Additionally we are shipping TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Antibodies (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TIAL1 7073 Q01085
TIAL1 21843 P70318
Rat TIAL1 TIAL1 361655  
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Top TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$413.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

TIAL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Interaction Partners

Human TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) interaction partners

  1. results suggest that TIA-1 and TIAR are two new host factors that interact with 5-UTR of EV71 genome and positively regulate viral replication

  2. TIAL1 inhibition of the exon 8 exclusion led to a decrease in SIRT1 (show SIRT1 Proteins)-Exon8 mRNA levels.

  3. TIA proteins can function as long-term regulators of the ACTB (show ACTB Proteins) mRNA metabolism in mouse and human cells.

  4. A role for TIAR is identified in T-cells for control of translational specificity.

  5. findings demonstrate that TIAR recognition motif 2 (RRM2 (show RRM2 Proteins)), together with its C-terminal extension, is the major contributor for the high-affinity (nM) interactions of TIAR with target RNA sequences

  6. TIA1 (show TIA1 Proteins) and TIAR proteins are intron-associated positive regulators of SMN2 (show SMN1 Proteins) exon 7 splicing.

  7. Severe hypoxia caused co-aggregation of TIAR/TIA-1 and these proteins suppressed HIF-1alpha (show HIF1A Proteins) expression.

  8. Data show that TIA1 (show TIA1 Proteins) and TIAL1 bind at the same positions on human RNAs, and are consistent with a model where TIA proteins shorten the time available for definition of an alternative exon by enhancing recognition of the preceding 5' splice site.

  9. Data show that apoptotic (TIAR and TIA-1 (show TIA1 Proteins)) marker expression in thyroid tissues from adolescents with immune thyroid diseases is higher than in non-immune thyroid diseases.

  10. results report the identification of TIAR as a novel player in the regulation of calcitonin/CGRP (show CALCA Proteins) alternative RNA processing

Mouse (Murine) TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) interaction partners

  1. Silencing of TIAR in chronic myeloid leukemia cells strongly elevated BRCA1.

  2. TIA proteins can function as long-term regulators of the ACTB (show ACTB Proteins) mRNA metabolism in mouse and human cells.

  3. Either TIA1 (show TIA1 Proteins) or TIAR inactivation broadly alter normal development-associated signalling pathways in murine embryonic fibroblasts.

  4. study reports the importance of the tightly balanced expression of the RNA-binding protein TIAR for normal embryonic development, thereby emphasizing the role of post-transcriptional regulations in early embryonic programming

  5. prion (show PRNP Proteins)-like aggregation of TIA-1 (show TIA1 Proteins) regulates stress granules formation downstream of eIF2alpha (show EIF2A Proteins) phosphorylation in response to stress

  6. in addition to transcriptional regulation, another mechanism by which apigenin prevents COX-2 expression is through mediating TIAR suppression of translatino

  7. TIAR regulates the relative expression of TIA-1 (show TIA1 Proteins) isoforms.

  8. TIA1 (show TIA1 Proteins) and TIAL1 regulate the alternate splicing of lysyl hydroxylase 2 (show PLOD2 Proteins)

  9. The intronic splicing enhancer of minute virus of mice binds the cellular RNA-processing proteins TIA-1 (show TIA1 Proteins) and TIAR, which enhance usage of the nonconsensus donor.

  10. SOD1 (show SOD1 Proteins) sequesters Hu antigen R (HuR (show ELAVL1 Proteins)) and TIA-1-related protein (TIAR) and has a role in impaired post-transcriptional regulation of vascular endothelial growth factor

TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) Protein Profile

Protein Summary

The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.

Gene names and symbols associated with TIAL1

  • TIA1 cytotoxic granule-associated RNA binding protein (TIA1)
  • TIA1 cytotoxic granule-associated RNA binding protein-like 1 (tial1)
  • TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1)
  • Tia1 cytotoxic granule-associated RNA binding protein-like 1 (Tial1)
  • 5330433G13Rik protein
  • AL033329 protein
  • mTIAR protein
  • TCBP protein
  • TIAL1 protein
  • tiar protein
  • zgc:66130 protein

Protein level used designations for TIAL1

TIA1 cytotoxic granule-associated RNA binding protein-like 1 , nucleolysin TIAR , T-cluster binding protein , TIA-1-related nucleolysin , aging-associated gene 7 protein , TIA-1-related protein , Tial1 cytotoxic granule-associated RNA binding protein-like 1 , Tial1 cytotoxic granule-associated RNA-binding protein-like 1 , RNA binding protein TIAR (TIA-1 related) , Tial 1 cytotoxic granule-associated RNA- binding protein-like 1

GENE ID SPECIES
771327 Gallus gallus
394107 Danio rerio
100381100 Xenopus laevis
7073 Homo sapiens
477841 Canis lupus familiaris
21843 Mus musculus
361655 Rattus norvegicus
614540 Bos taurus
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