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TIMP Metallopeptidase Inhibitor 1 (TIMP1) ELISA Kits

TIMP1 belongs to the TIMP gene family. Additionally we are shipping TIMP1 Antibodies (1) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TIMP1 TIMP1 7076 P01033
Anti-Rat TIMP1 TIMP1 116510 P30120
Anti-Mouse TIMP1 TIMP1 21857 P12032
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More ELISA Kits for TIMP1 Interaction Partners

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. suggest better clinical usefulness of MMP-9 (show MMP9 ELISA Kits) and TIMP-1 expression in cholesteatoma tissues than either serum or plasma levels of these proteins

  2. These results suggest that in the progression of renal aging, high expression of TIMP-1 up-regulates PTEN expression indicating that PTEN and TIMP-1 are involved in the aging-associated impairment of renal angiogenesis

  3. MMP-1 (show MMP1 ELISA Kits) expression is increased in intervertebral disc degeneration, with higher expression observed in more severe cases, whereas TIMP-1 expression was similarly expressed in both normal and degenerated discs.

  4. Metformin simultaneously increases VEGFA (show VEGFA ELISA Kits) and reduces CXCL10 (show CXCL10 ELISA Kits) and TIMP1 in CD34 (show CD34 ELISA Kits)(+) cells in a model of the diabetic state combined with hypoxia to stimulate angiogenesis.

  5. It demonstrated that MMP-9 (show MMP9 ELISA Kits) to TIMP-1 ratio was positively associated with body weight and waist circumference 3 years after a 12-week low-calorie-diet weight-reduction program in men with metabolic syndrome.

  6. These results show that increased MMP-8 (show MMP8 ELISA Kits) and decreased TIMP-1 expressions are closely related to the invasive pituitary adenoma, and can be helpful for the evaluation.

  7. Genes expression of MMP9 (show MMP9 ELISA Kits), VEGFA (show VEGFA ELISA Kits) and TIMP1 in peripheral blood leukocytes may play a pivotal role in regulation of progression of bladder cancer; TIMP1 expression may be important factor for early recurrence.

  8. High TIMP1 expression is associated with Sepsis.

  9. Data show that serum neuron-specific enolase (show ENO2 ELISA Kits), cytokeratin 19 (show KRT19 ELISA Kits) fragment 21-1, pro-gastrin-releasing peptide (show GRP ELISA Kits), squamous cell carcinoma antigen, tissue inhibitor of metalloproteinase-1, and human epididymis protein 4 are not associated with brain metastases.

  10. association of the TIMP-1 gene with recurrent aphthous stomatitis was ruled out based on our results.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Decreased MMP-9 (show MMP9 ELISA Kits) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (show EGF ELISA Kits) on MMP-9 (show MMP9 ELISA Kits) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (show TNF ELISA Kits), and hepatocyte growth factor (show HGF ELISA Kits) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (show TIMP2 ELISA Kits) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (show TIMP2 ELISA Kits) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (show TIMP2 ELISA Kits) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (show MMP9 ELISA Kits), TIMP1, and NGAL (show LCN2 ELISA Kits) (also MMP2 (show MMP2 ELISA Kits) in 220 kDa complex) without proteolytic activity.

  2. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (show VEGFA ELISA Kits), pro-MMP-9 (show MMP9 ELISA Kits), MMP-2 (show MMP2 ELISA Kits), VEGFR-1 (show FLT1 ELISA Kits), VEGFR-2 (show KDR ELISA Kits), and TIMP-1, which may contribute to the development of venous stenosis.

  3. Results indicate that leukemia inhibitory factor (LIF (show LIF ELISA Kits)) and Oncostatin M (show OSM ELISA Kits) increase the expression of MMP-1 (show MMP1 ELISA Kits), MMP-3 (show MMP3 ELISA Kits), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF ELISA Kits) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (show MMP2 ELISA Kits), MMP-9 (show MMP9 ELISA Kits) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (show CD63 ELISA Kits).

  2. TIMP-1 is a ligand of LRP-1 (show LRP1 ELISA Kits) and we highlight a new example of its MMP-independent, cytokine-like functions.

  3. RAB37 (show RAB37 ELISA Kits) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (show MMP9 ELISA Kits) migration axis in vitro and in vivo and to suppress tumor metastasis.

  4. PDGF-D (show PDGFD ELISA Kits) intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2 (show MMP2 ELISA Kits)/MMP (show MMP2 ELISA Kits)-9 (show MMP9 ELISA Kits) system, and PDGF-D (show PDGFD ELISA Kits) signaling is mediated through both PDGF (show PDGFA ELISA Kits)-alpha and -beta receptors.

  5. Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (show MAPK14 ELISA Kits) signaling pathway.

  6. Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 (show TIMP3 ELISA Kits)-deficient mice.

  7. TNF-alpha (show TNF ELISA Kits) produced by cholestasis can promote liver fibrosis via TIMP-1 production from hepatic stellate cells.

  8. These data suggest an MMP-independent role of TIMP-1 in regulating CD4 (show CD4 ELISA Kits) T cell access into the CNS parenchyma during acute JHMV encephalitis

  9. miR (show MLXIP ELISA Kits)-21 contributes to renal fibrosis by mediating MMP9 (show MMP9 ELISA Kits)/TIMP1

  10. Gene expression of Mmp-12 (show MMP12 ELISA Kits) and Mmp-13 (show MMP13 ELISA Kits), and Timp-1 was strongly upregulated at all time points in RD compared with controls. Timp-2 (show TIMP2 ELISA Kits), Mmp-2 (show MMP2 ELISA Kits), and Mmp-9 (show MMP9 ELISA Kits) expression was modest.

TIMP1 Antigen Profile

Antigen Summary

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Gene names and symbols associated with TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) antibody
  • TIMP metallopeptidase inhibitor 1 (Timp1) antibody
  • tissue inhibitor of metalloproteinase 1 (LOC100009047) antibody
  • tissue inhibitor of metalloproteinase 1 (Timp1) antibody
  • Clgi antibody
  • DKFZp468A0912 antibody
  • EPA antibody
  • EPO antibody
  • HCI antibody
  • Timp antibody
  • TIMP-1 antibody
  • TIMP1 antibody

Protein level used designations for TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

GENE ID SPECIES
574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
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