TNF Receptor-Associated Factor 4 (TRAF4) ELISA Kits

TRAF4 encodes a member of the TNF receptor associated factor (TRAF) family. Additionally we are shipping TRAF4 Antibodies (78) and TRAF4 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TRAF4 TRAF4 9727 O75154
Anti-Mouse TRAF4 TRAF4 22032 Q61382
Anti-Rat TRAF4 TRAF4 303285  
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More ELISA Kits for TRAF4 Interaction Partners

Human TNF Receptor-Associated Factor 4 (TRAF4) interaction partners

  1. miR (show MLXIP ELISA Kits)-4443 acts in a tumor-suppressive manner by down-regulating TRAF4 and NCOA1 (show NCOA1 ELISA Kits) downstream of MEK (show MAP2K1 ELISA Kits)-C/EBP (show CEBPA ELISA Kits)-mediated leptin (show LEP ELISA Kits) and insulin (show INS ELISA Kits) signaling, and that insulin (show INS ELISA Kits) and/or leptin (show LEP ELISA Kits) resistance (e.g. in obesity) may suppress this pathway and increase the risk of metastatic CRC (show CALR ELISA Kits).

  2. Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation

  3. RAB11FIP3 (show RAB11FIP3 ELISA Kits) combines with Eps15 (show EPS15 ELISA Kits) homology domain 1 to promote the endocytosis recycling of phosphorylation of epithelial growth factor receptor (show RYK ELISA Kits).

  4. TRAF4 expression is higher in mastocytosis patients with food hypersensitivity in their medical history, while B3GAT1 (show B3GAT1 ELISA Kits) expression is lower in mastocytosis patients with insect venom allergy in history

  5. Determined the crystal structure of TRAF (show TRAF1 ELISA Kits) domain of TRAF4 (residues 292-466) at 2.60 A resolution by X-ray crystallography method. The trimericly assembled TRAF4 resembles a mushroom shape, containing a super helical "stalk" which is made of three right-handed intertwined alpha helixes and a C-terminal "cap", which is divided at residue L302 as a boundary.

  6. TRAF4 may promote oral squamous carcinoma cell growth, invasion and migration by Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway.

  7. There was a significant positive correlation between TRAF2 (show TRAF2 ELISA Kits) and TRAF4 expression levels in malignant pleural effusion cells

  8. The TRAF4-ERK (show IL17A ELISA Kits)5 is a dominant pathway in human skin squamous cell carcinoma.

  9. Rab11-FIP3 coordinates the interactions of ASAP1 and Rab11a with Rabin8.

  10. Data showed that TRAF4 was highly expressed in non-small cell lung cancer (NSCLC) cells, and miR (show MLXIP ELISA Kits)-370 overexpression significantly inhibited its expression. These results suggest that TRAF4 serves as an oncogene (show RAB1A ELISA Kits) in NSCLC.

Mouse (Murine) TNF Receptor-Associated Factor 4 (TRAF4) interaction partners

  1. A novel IL-17 (show IL17A ELISA Kits) signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 (show MAPK7 ELISA Kits) axis.

  2. Data indicate that TNF receptor associated factor 4 (TRAF4) recruited the E3-ligase SMURF2 (show SMURF2 ELISA Kits), to degrade the IL-25R-inhibitory molecule DAZ associated protein 2 (DAZAP2 (show DAZAP2 ELISA Kits)).

  3. Like IKKalpha (show CHUK ELISA Kits), TRAF4 is atypical within its family because it is the only TRAF (show TRAF1 ELISA Kits) family member to negatively regulate innate immune signaling. IKKalpha's phosphorylation of serine-426 on TRAF4 was required for this negative regulation.

  4. Report divergent effects of p47(phox) phosphorylation at S303-4 or S379 on tumor necrosis factor-alpha (show TNF ELISA Kits) signaling via TRAF4 and MAPK (show MAPK1 ELISA Kits) in endothelial cells.

  5. These results provide conclusive evidence for the pivotal contribution of TRAF4 to myelination.

  6. enhances TNF-alpha (show TNF ELISA Kits) translation

  7. A novel motif in the Crohn's disease susceptibility protein, NOD2 (show NOD2 ELISA Kits), allows TRAF4 to down-regulate innate immune responses.

  8. Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.

  9. TRAF4 may play a role in p53 (show TP53 ELISA Kits)-mediated proapoptotic signaling in the response to cellular stress

  10. MEKK4 (show MAP3K4 ELISA Kits) is the MAPK (show MAPK1 ELISA Kits) kinase kinase for TRAF4 regulation of the JNK (show MAPK8 ELISA Kits) pathway

Zebrafish TNF Receptor-Associated Factor 4 (TRAF4) interaction partners

  1. cloning of two zebrafish orthologs of the human traf4, traf4a and traf4b; during embryogenesis, traf4b expression is present in a weak ubiquitous manner

TRAF4 Antigen Profile

Antigen Summary

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

Gene names and symbols associated with TRAF4

  • RAB11 family interacting protein 3 (class II) (RAB11FIP3) antibody
  • TNF receptor associated factor 4 (Traf4) antibody
  • Tnf receptor associated factor 4 (Traf4) antibody
  • TNF receptor-associated factor 4 (TRAF4) antibody
  • TNF receptor-associated factor 4 (traf4-a) antibody
  • tnf receptor-associated factor 4b (traf4b) antibody
  • A530032M13Rik antibody
  • cart1 antibody
  • mln62 antibody
  • msp2 antibody
  • Rab11-FIP3 antibody
  • rnf83 antibody
  • traf-4 antibody
  • traf4 antibody

Protein level used designations for TRAF4

EF hands-containing Rab-interacting protein , FIP3-Rab11 , MU-MB-17.148 , PAC196A12.1 , arfophilin-1 , cytoplasmic adaptor for RAR and TR , eferin , rab11 family-interacting protein 3 , rab11-family interacting protein 3 , TNF receptor-associated factor 4 , cysteine-rich motif associated to RING and Traf domains protein 1 , MLN 62 , RING finger protein 83 , cysteine-rich domain associated with RING and Traf domains protein 1 , cysteine-rich domain associated with ring and TRAF domain , malignant 62 , metastatic lymph node gene 62 protein , tumor necrosis receptor-associated factor 4A

9727 Homo sapiens
22032 Mus musculus
303285 Rattus norvegicus
9618 Homo sapiens
447325 Xenopus laevis
100688511 Canis lupus familiaris
781568 Bos taurus
404035 Danio rerio
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