anti-TNF Receptor-Associated Protein 1 (TRAP1) Antibodies

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. Additionally we are shipping TNF Receptor-Associated Protein 1 Proteins (12) and TNF Receptor-Associated Protein 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRAP1 10131 Q12931
TRAP1 68015 Q9CQN1
TRAP1 287069 Q5XHZ0
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Top anti-TNF Receptor-Associated Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 174 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB Human kidney WB Suggested Anti-TRAP1 Antibody Titration: 0.5ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate TRAP1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB TRAP1 Antibody (C-term) (ABIN658049) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the TRAP1 antibody detected the TRAP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, IF, WB Trap1 HS Hela 20ug 1 in 1000 Western Blotting. 100 μg Log in to see 2 to 3 Days
$360.80
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-TRAP1 Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole Cell TRAP1 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Figure 2 shows an immunoprecipitation of TRAP1 using ABIN152714 visualized by Coomassie Blue staining. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Dog Mouse Un-conjugated IF, WB Western blot analysis of Hsp75 on HeLa lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of Hsp75. Immunofluorescence staining of HeLa cells. 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- TRAP1 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit HRP ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-TRAP1 Polyclonal Antibody . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Rabbit Anti-TRAP1 Polyclonal Antibody  at 1:120 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Mitochondrion. Mitochondrion inner membrane. Mitochondrion matrix. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-TRAP1 Antibody. (C) Composite. Heat Shocked at 42°C for 1h. Western blot analysis of Human Cervical Cancer cell lysates (HeLa) showing detection of ~75 kDa TRAP1 protein using Rabbit Anti-TRAP1 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Human Cervical Cancer cell lysates (HeLa). Load: 12 µg. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-TRAP1 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: ~75 kDa. Other Band(s): 100 kDa. 100 μg Log in to see 2 to 3 Days
$399.30
Details
Human Rabbit FITC ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-TRAP1 Polyclonal Antibody . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Rabbit Anti-TRAP1 Polyclonal Antibody  at 1:120 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Mitochondrion. Mitochondrion inner membrane. Mitochondrion matrix. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-TRAP1 Antibody. (C) Composite. Heat Shocked at 42°C for 1h. Western blot analysis of Human Cervical Cancer cell lysates (HeLa) showing detection of ~75 kDa TRAP1 protein using Rabbit Anti-TRAP1 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Human Cervical Cancer cell lysates (HeLa). Load: 12 µg. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-TRAP1 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: ~75 kDa. Other Band(s): 100 kDa. 100 μg Log in to see 2 to 3 Days
$403.70
Details
Human Rabbit Alkaline Phosphatase (AP) ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-TRAP1 Polyclonal Antibody . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Rabbit Anti-TRAP1 Polyclonal Antibody  at 1:120 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Mitochondrion. Mitochondrion inner membrane. Mitochondrion matrix. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-TRAP1 Antibody. (C) Composite. Heat Shocked at 42°C for 1h. Western blot analysis of Human Cervical Cancer cell lysates (HeLa) showing detection of ~75 kDa TRAP1 protein using Rabbit Anti-TRAP1 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Human Cervical Cancer cell lysates (HeLa). Load: 12 µg. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-TRAP1 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: ~75 kDa. Other Band(s): 100 kDa. 100 μg Log in to see 2 to 3 Days
$405.90
Details

TRAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TNF Receptor-Associated Protein 1 Antibodies

  1. Human Polyclonal TRAP1 Primary Antibody for ICC, IF - ABIN2482022 : Felts, Owen, Nguyen, Trepel, Donner, Toft: The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for 2482022

  2. Human Polyclonal TRAP1 Primary Antibody for ICC, IF - ABIN2482021 : Costantino, Maddalena, Calise, Piscazzi, Tirino, Fersini, Ambrosi, Neri, Esposito, Landriscina: TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells. in Cancer letters 2009 (PubMed)
    Show all 3 references for 2482021

  3. Human Monoclonal TRAP1 Primary Antibody for ICC, IF - ABIN863110 : Cechetto, Gupta: Immunoelectron microscopy provides evidence that tumor necrosis factor receptor-associated protein 1 (TRAP-1) is a mitochondrial protein which also localizes at specific extramitochondrial sites. in Experimental cell research 2000 (PubMed)
    Show all 3 references for 863110

  4. Dog (Canine) Monoclonal TRAP1 Primary Antibody for IF, WB - ABIN968825 : Chen, Chen, Dai, Chen, Riley, Lee: A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock. in Molecular and cellular biology 1996 (PubMed)
    Show all 3 references for 968825

  5. Human Monoclonal TRAP1 Primary Antibody for ICC, IF - ABIN152714 : Hamacher-Brady, Choe, Krijnse-Locker, Brady: Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase. in Cell death and differentiation 2014 (PubMed)
    Show all 2 references for 152714

  6. Human Polyclonal TRAP1 Primary Antibody for IHC (p), WB - ABIN658049 : Leav, Plescia, Goel, Li, Jiang, Cohen, Languino, Altieri: Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer. in The American journal of pathology 2009 (PubMed)

  7. Dog (Canine) Polyclonal TRAP1 Primary Antibody for IHC, WB - ABIN2792093 : Masuda, Shima, Aiuchi, Horie, Hori, Nakajo, Kajimoto, Shibayama-Imazu, Nakaya: Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against TNF Receptor-Associated Protein 1 Interaction Partners

Human TNF Receptor-Associated Protein 1 (TRAP1) interaction partners

  1. TRAP1 is often deleted in high-grade serous ovarian cancer patients.

  2. TRAP1 increases cell proliferation, reduces apoptosis, and promotes cell invasion without changes in mitochondrial bioenergetics. Therefore, TRAP1 is a driver of prostate cancer in vivo and an "actionable" therapeutic target.

  3. overexpression of TRAP1 might contribute to tumor cell local invasion of colorectal cancer

  4. Increased TRAP1 expression was significantly associated with EOC stages.

  5. Overexpression of TRAP1 in breast cancer cells causes mitochondrial fusion, triggers mitochondria to form tubular networks, and suppresses cell migration and invasion in vitro and in vivo. These data link TRAP1-regulated mitochondrial dynamics and function with tumorigenesis in breast cancer.

  6. TRAP1 is highly expressed in kidney cancer and correlates with patients prognosis

  7. TRAP1 is a downstream effector of BRAF (show BRAF Antibodies) cytoprotective pathway in mitochondria and TRAP1 targeting may represent a novel strategy to improve the activity of proapoptotic agents in BRAF (show BRAF Antibodies)-driven CRC (show CALR Antibodies) cells.

  8. the association of rs2679860 polymorphisms of TGFBRAP1 (show TGFBRAP1 Antibodies) and DBP (show GC Antibodies) variation as well as plasma levels of TGF-beta1 (show TGFB1 Antibodies)

  9. Our results indicate that GRP94 (show HSP90B1 Antibodies) and TRAP1 might contribute more to the carcinogenesis or biology of SCLC than HSP90alpha (show HSP90AA2 Antibodies) and HSP90beta (show HSP90AB1 Antibodies)

  10. A previously unobserved coiled-coil dimer conformation may precede dimer closure. TRAP1 exists in an autoinhibited state with the ATP lid bound to the ATP-binding pocket. ATP displaces this and signals the cis (show CISH Antibodies)-bound ATP status to the next subunit.

Mouse (Murine) TNF Receptor-Associated Protein 1 (TRAP1) interaction partners

  1. TRAP1 increases cell proliferation, reduces apoptosis, and promotes cell invasion without changes in mitochondrial bioenergetics. Therefore, TRAP1 is a driver of prostate cancer in vivo and an "actionable" therapeutic target.

  2. Data show that the overexpression of heat shock protein 75 (Hsp75) decreased neural stem cells (NSCs) apoptosis and preserved mitochondrial membrane potential.

  3. TRAP-1-/- mice are viable and show reduced incidence of age-associated pathologies. Loss of TRAP-1 upregulates oxidative phosphorylation and glycolysis transcriptomes.

  4. overexpression of TRAP1 leads to mitochondrial aberrations, including an increase in basal ROS (show ROS1 Antibodies) levels and decrease in mitochondrial biogenesis, together with a decrease in peroxisome proliferator-activated receptor gamma (show PPARG Antibodies) coactivator-1alpha mRNA levels

  5. Early mesangial nephritis initiates a cascade of inflammatory signals that lead to up-regulation of Trap1 and a consequent down-regulation of renal DNaseI (show DNASE1 Antibodies) by transcriptional interference.

  6. TRAP1 regulates a metabolic switch between oxidative phosphorylation and aerobic glycolysis in immortalized mouse fibroblasts.

  7. These data identify TRAP-1 as a novel mitochondrial survival factor differentially expressed in localized and metastatic prostate cancer compared with normal prostate.

TNF Receptor-Associated Protein 1 (TRAP1) Antigen Profile

Protein Summary

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with TRAP1

  • TNF receptor-associated protein 1 (TRAP1) antibody
  • TNF receptor-associated protein 1 (Trap1) antibody
  • transforming growth factor, beta receptor associated protein 1 (TGFBRAP1) antibody
  • 2410002K23Rik antibody
  • HSP 75 antibody
  • HSP75 antibody
  • HSP90L antibody
  • TRAP-1 antibody
  • TRAP1 antibody

Protein level used designations for TRAP1

TNFR-associated protein 1 , heat shock protein 75 kDa, mitochondrial , tumor necrosis factor type 1 receptor-associated protein , HSP 75 , TRAP-1 , tumor necrosis factor type 1 receptor associated protein , TGF beta receptor associated protein -1 , TGF-beta receptor-associated protein 1 , transforming growth factor-beta receptor-associated protein 1

GENE ID SPECIES
10131 Homo sapiens
416666 Gallus gallus
68015 Mus musculus
287069 Rattus norvegicus
514472 Bos taurus
490032 Canis lupus familiaris
9392 Homo sapiens
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