TNF Receptor-Associated Protein 1 (TRAP1) ELISA Kits

TRAP1 encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. Additionally we are shipping TNF Receptor-Associated Protein 1 Antibodies (189) and TNF Receptor-Associated Protein 1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TRAP1 10131 Q12931
TRAP1 68015 Q9CQN1
TRAP1 287069 Q5XHZ0
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Top TNF Receptor-Associated Protein 1 ELISA Kits at antibodies-online.com

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Human
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$875.60
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Mouse
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$875.60
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Rat
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$875.60
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More ELISA Kits for TNF Receptor-Associated Protein 1 Interaction Partners

Human TNF Receptor-Associated Protein 1 (TRAP1) interaction partners

  1. data show that TRAP1 acts downstream of PINK1 and HTRA2 for mitochondrial fine tuning, whereas TRAP1 loss of function leads to reduced control of energy metabolism, ultimately impacting mitochondrial membrane potential.

  2. This review summarizes how metabolism, chemoresistance, inflammation, and epithelial-to-mesenchymal transition are strictly interconnected, and how TRAP1 stays at the crossroads of these processes, thus shedding new lights on molecular networks at the basis of ovarian cancer. [review]

  3. These data suggest that TRAP1 protein network may provide a prognostic signature in human metastatic colorectal carcinomas

  4. TRAP1 is relevant in the control of key cell cycle regulators in tumor cells. TRAP1/TBP7 (show PSMC4 ELISA Kits) quality control of CDK1 (show CDK1 ELISA Kits) and MAD2 (show MAD2L1 ELISA Kits) contributes mechanistically to the regulation of mitotic entry and transit.

  5. MFSD2B, CCL20 (show CCL20 ELISA Kits) and STAT1 (show STAT1 ELISA Kits), or STARD7 and ZNF512 (show ZNF512 ELISA Kits) genes may be risk or protect factors in prognosis of ADC (show ADC ELISA Kits); HTR2B (show HTR2B ELISA Kits), DPP4 (show DPP4 ELISA Kits), and TGFBRAP1 (show TGFBRAP1 ELISA Kits) genes may be risk factors in prognosis of SQC (show QPCT ELISA Kits).

  6. TRAP1 is often deleted in high-grade serous ovarian cancer patients.

  7. TRAP1 increases cell proliferation, reduces apoptosis, and promotes cell invasion without changes in mitochondrial bioenergetics. Therefore, TRAP1 is a driver of prostate cancer in vivo and an "actionable" therapeutic target.

  8. overexpression of TRAP1 might contribute to tumor cell local invasion of colorectal cancer

  9. Increased TRAP1 expression was significantly associated with EOC stages.

  10. Overexpression of TRAP1 in breast cancer cells causes mitochondrial fusion, triggers mitochondria to form tubular networks, and suppresses cell migration and invasion in vitro and in vivo. These data link TRAP1-regulated mitochondrial dynamics and function with tumorigenesis in breast cancer.

Mouse (Murine) TNF Receptor-Associated Protein 1 (TRAP1) interaction partners

  1. show that TRAP1 could protect the mitochondrial structure in renal tubular epithelial cells; maintain the levels of mitochondrial membrane potential, ATP, and mitochondrial DNA copy number

  2. TRAP1 increases cell proliferation, reduces apoptosis, and promotes cell invasion without changes in mitochondrial bioenergetics. Therefore, TRAP1 is a driver of prostate cancer in vivo and an "actionable" therapeutic target.

  3. Data show that the overexpression of heat shock protein 75 (Hsp75) decreased neural stem cells (NSCs) apoptosis and preserved mitochondrial membrane potential.

  4. TRAP-1-/- mice are viable and show reduced incidence of age-associated pathologies. Loss of TRAP-1 upregulates oxidative phosphorylation and glycolysis transcriptomes.

  5. overexpression of TRAP1 leads to mitochondrial aberrations, including an increase in basal ROS (show ROS1 ELISA Kits) levels and decrease in mitochondrial biogenesis, together with a decrease in peroxisome proliferator-activated receptor gamma (show PPARG ELISA Kits) coactivator-1alpha mRNA levels

  6. Early mesangial nephritis initiates a cascade of inflammatory signals that lead to up-regulation of Trap1 and a consequent down-regulation of renal DNaseI (show DNASE1 ELISA Kits) by transcriptional interference.

  7. TRAP1 regulates a metabolic switch between oxidative phosphorylation and aerobic glycolysis in immortalized mouse fibroblasts.

  8. These data identify TRAP-1 as a novel mitochondrial survival factor differentially expressed in localized and metastatic prostate cancer compared with normal prostate.

TNF Receptor-Associated Protein 1 (TRAP1) Antigen Profile

Antigen Summary

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with TRAP1

  • TNF receptor associated protein 1 (TRAP1) antibody
  • TNF receptor-associated protein 1 (Trap1) antibody
  • TNF receptor-associated protein 1 (TRAP1) antibody
  • TNF receptor associated protein 1 (Trap1) antibody
  • TNF receptor-associated protein 1 (trap1) antibody
  • 2410002K23Rik antibody
  • fc85a11 antibody
  • HSP 75 antibody
  • HSP75 antibody
  • HSP90L antibody
  • TRAP-1 antibody
  • wu:fc85a11 antibody

Protein level used designations for TRAP1

TNFR-associated protein 1 , heat shock protein 75 kDa, mitochondrial , tumor necrosis factor type 1 receptor-associated protein , HSP 75 , TRAP-1 , tumor necrosis factor type 1 receptor associated protein

GENE ID SPECIES
10131 Homo sapiens
68015 Mus musculus
287069 Rattus norvegicus
416666 Gallus gallus
514472 Bos taurus
490032 Canis lupus familiaris
100718722 Cavia porcellus
571959 Danio rerio
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