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TNIP1 encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Additionally we are shipping TNFAIP3 Interacting Protein 1 Proteins (12) and TNFAIP3 Interacting Protein 1 Kits (1) and many more products for this protein.
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Human Polyclonal TNIP1 Primary Antibody for EIA, IHC (p) - ABIN955281
Yu, Vajdy: Mucosal HIV transmission and vaccination strategies through oral compared with vaginal and rectal routes. in Expert opinion on biological therapy 2010
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Data show that proto-oncogene transcription factor Ets1 regulates neural crest development through histone deacetylase 1 HDAC1) to down-regulate bone morphogenetic protein (BMP) signaling output and reduce id3 protein expression.
Polymorphisms in TNIP1 are associated with GPP in Chinese Han population. However, no association with PPP was found. These findings suggest that TNIP1 might be a susceptibility gene for GPP.
The findings of this study suggested that TNIP1 is a new potential predisposing gene to spina bifida (SB) and its pathway needs to be investigated in human NTD in order to confirm its role and to plan appropriate counseling to families
Data suggest that reduced TNFalpha (show TNF Antibodies)-induced protein 3 (show HSPB3 Antibodies)-interacting protein 1 (TNIP1) expression may have a role in the pathogenesis of myasthenia gravis (MG)for patients with thymoma.
HIV-1 depends on host-cell-encoded factors to complete its life cycle; data suggest that nucleus-located NAF1/TNIP1 promotes nuclear export of un-spliced HIV-1 gag mRNA; association between NAF1/TNIP1 and CRM1 (show XPO1 Antibodies) is required for this function.
Hepatitis C virus antigen stimulation up-regulates A20/A20 (show TNFAIP3 Antibodies)-binding inhibitor of NF-kappaB (show NFKB1 Antibodies) binding protein expression, which consequently contributes to inefficient M1 macrophage polarization.
Data suggest that tumour necrosis factor alpha (show TNF Antibodies)-induced protein 3 (show HSPB3 Antibodies) (TNFAIP3 (show TNFAIP3 Antibodies)) and TNFAIP3-interacting protein 1 (TNIP1) single nucleotide polymorphisms (SNPs) confer increased risk of psoriasis in ethnic South Indian Tamils.
Since TNIP1 may facilitate the function of TNFAIP3 (show TNFAIP3 Antibodies) in the negative feedback regulation of NF-kappaB (show NFKB1 Antibodies) activation , the corresponding transcript levels of TNIP1 in psoriasis vul- garis were investigated in this study.
The aim of this study was to investigate whether the HCP5, TNIP1, TNFAIP3 (show TNFAIP3 Antibodies), SPATA2 (show SPATA2 Antibodies) and COG6 (show COG6 Antibodies) genes were genetic risk factors for psoriasis in Chinese population.
Single-nucleotide polymorphisms rs7708392 and rs495881 in TNIP1 were significantly associated with Lupus Nephritis in individuals with European or African ancestry.
HSPA6 (show HSPA6 Antibodies) regulation by TNIP1 occurs in promoter regions lacking binding sites for known TNIP1-repressed transcription factors
These results suggest that the ABIN1-mediated hyperactivation of IKKs and MAPKs might mediate chronic inflammation and CVD development.
studies link ABIN-1 with IL-23 (show IL23A Antibodies) and IL-17 (show IL17A Antibodies), and they provide cellular and molecular mechanisms by which ABIN-1 regulates susceptibility to psoriasis.
data reveal ABIN1 as an essential anti-inflammatory component of TLR-signaling pathways that controls C/EBPbeta (show CEBPB Antibodies) activity
ABIN1 requires its ubiquitin binding domain and cooperates with TAX1BP1 (show TAX1BP1 Antibodies) and A20 (show TNFAIP3 Antibodies) to restrict antiviral signaling.
the interaction of ABIN1 with polyubiquitin (show UBB Antibodies) is required to limit the activation of TLR-MyD88 (show MYD88 Antibodies) pathways and prevent autoimmunity
Using a murine model of allergen-induced asthma, we have demonstrated that adenovirus-mediated delivery of ABIN-1 to the lung epithelium results in a reduction of allergen-induced eosinophil infiltration into the lungs.
ABIN-1 inhibits caspase 8 (show CASP8 Antibodies) recruitment to FADD (show FADD Antibodies) (Fas (show FAS Antibodies)-associated death domain-containing protein) in TNF (show TNF Antibodies)-induced signalling complexes, preventing caspase 8 (show CASP8 Antibodies) cleavage and programmed cell death.
we cloned the pig ABIN-1 gene to investigate its potential effects on pig reproduction traits.
This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.
, Nef-associated factor 1
, TNFAIP3-interacting protein 1
, TNFAIP3 interacting protein 1
, TNFAIP3-interacting protein 1-like
, A20-binding inhibitor of NF-kappa-B activation 1
, HIV-1 Nef-interacting protein
, Nef-associated factor 1 SNP
, virion-associated nuclear shuttling protein
, A20-binding inhibitor of NF-kappa B activation
, A20 binding and inhibitor of NF-kB protein 1
, c-ets-1 oncogene
, p54 transcription factor
, protein C-ets-1
, transforming protein p54/c-ets-1
, transforming protein p68/c-ets-1
, virion-associated nuclear-shuttling protein