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anti-TNNI3 Interacting Kinase (TNNI3K) Antibodies

kinase enzyme; interacts specifically with cardiac troponin I; human homolog is a cardiac specific kinase. Additionally we are shipping TNNI3 Interacting Kinase Proteins (5) and TNNI3 Interacting Kinase Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNNI3K 51086 Q59H18
TNNI3K 435766 Q5GIG6
TNNI3K 295531 Q7TQP6
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Top anti-TNNI3 Interacting Kinase Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TNNI3K Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TNNI3K Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-TNNI3K  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TNNI3K, antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: HeLaS3 7.5% SDS PAGE antibody diluted at 1:5000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Tnni3k AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TNNI3K Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of CARK staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CARK expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

TNNI3K Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TNNI3 Interacting Kinase Antibodies

  1. Cow (Bovine) Polyclonal TNNI3K Primary Antibody for WB - ABIN2783205 : Feng, Liu, Wang, Liu, Cao, Wang, Shi, Meng: AOP-1 interacts with cardiac-specific protein kinase TNNI3K and down-regulates its kinase activity. in Biochemistry. Biokhimii͡a 2008 (PubMed)

More Antibodies against TNNI3 Interacting Kinase Interaction Partners

Human TNNI3 Interacting Kinase (TNNI3K) interaction partners

  1. using novel genetic animal models and newly developed small-molecule TNNI3K inhibitors, we demonstrated that TNNI3K-mediated IR injury occurs through impaired mitochondrial function and is in part dependent on p38 MAPK (show MAPK14 Antibodies).

  2. we demonstrate that mutation of TNNI3K, encoding a heart-specific kinase known to modulate murine cardiac conduction and myocardial function, underlies a familial syndrome of electrical and myopathic heart disease in humans.

  3. TNNI3K mediates cell signaling to modulate cardiac response to stress.

  4. Results suggest that TNNI3K overexpression induces cardiomyocytes hypertrophy and accelerates hypertrophy in hypertrophic cardiomyocytes.

  5. The finding of a de novo mutation in TNNI3 (show TNNI3 Antibodies) (R204H) enabled a genetic diagnosis and counselling. We suggest that the previously reported overlap of functional and morphologic phenotypes in sarcomeric genes may also be a feature of TNNI3 (show TNNI3 Antibodies) mutations.

  6. [review] TNNI3K is a novel cardiac troponin I-interacting kinase gene that may be involved in the development of cardiac hypertrophy.

  7. cloning of TNNI3K which interacts specifically with cardiac troponin I (show TNNI3 Antibodies); data suggest that TNNI3K is a cardiac-specific kinase and plays important roles in the cardiac system

  8. TNNI3K exhibits dual-specific kinase activity and forms dimers or oligomers that may be necessary for its activation

  9. coexpression of AOP-1 (show PRDX3 Antibodies) inhibited TNNI3K kinase activity

  10. TNNI3K promotes cardiomyogenesis, enhances cardiac performance, and protects the myocardium from ischemic injury by suppressing p38 (show CRK Antibodies)/JNK (show MAPK8 Antibodies)-mediated apoptosis.

Mouse (Murine) TNNI3 Interacting Kinase (TNNI3K) interaction partners

  1. using novel genetic animal models and newly developed small-molecule TNNI3K inhibitors, we demonstrated that TNNI3K-mediated IR injury occurs through impaired mitochondrial function and is in part dependent on p38 MAPK (show MAPK14 Antibodies).

  2. Our data provide the first evidence for a role of Tnni3k in controlling the electrocardiographic PR interval indicating a function of Tnni3k in atrio-ventricular conduction

  3. Data identified Tnni3k, Fpgt (show FPGT Antibodies) and H28 (show IFI44L Antibodies) as likely likely candidates for Vms1.

  4. Tnni3k plays a critical role in the modulation of different forms of heart disease, and this protein may provide a novel target for therapeutic intervention.

TNNI3 Interacting Kinase (TNNI3K) Antigen Profile

Protein Summary

This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.

Gene names and symbols associated with TNNI3K

  • TNNI3 interacting kinase (TNNI3K) antibody
  • TNNI3 interacting kinase (Tnni3k) antibody
  • Cark antibody
  • D830019J24Rik antibody

Protein level used designations for TNNI3K

serine/threonine-protein kinase TNNI3K , TNNI3 interacting kinase , cardiac ankyrin repeat kinase , cardiac troponin I-interacting kinase , TNNI3-interacting kinase

GENE ID SPECIES
100533999 Gallus gallus
100592286 Nomascus leucogenys
51086 Homo sapiens
535940 Bos taurus
435766 Mus musculus
295531 Rattus norvegicus
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