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anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) Antibodies

Spindle assembly factor. Additionally we are shipping TPX2 Proteins (5) and TPX2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TPX2 22974 Q9ULW0
TPX2 311546  
TPX2 72119 A2APB8
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Top anti-TPX2 Antibodies at antibodies-online.com

Showing 10 out of 157 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TPX2 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB TPX2 Antibody (Center) (ABIN658474) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the TPX2 antibody detected the TPX2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using DIL-2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DIL-2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IP, SimWes, WB Staining of HeLa cells fixed in 3.5% paraformaldehyde using ABIN152993 (1:1,000).  Nuclear staining during interphase and spindle staining during mitosis. 0.025 mL Log in to see 5 to 7 Days
$178.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with TPX2 antibody ABIN239857 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

TPX2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-TPX2 Antibodies

  1. Human Polyclonal TPX2 Primary Antibody for FACS, ICC - ABIN268908 : Heidebrecht, Buck, Steinmann, Sprenger, Wacker, Parwaresch: p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M. in Blood 1997 (PubMed)
    Show all 20 references for ABIN268908

  2. Human Polyclonal TPX2 Primary Antibody for EIA, IHC (p) - ABIN357426 : Heidebrecht, Adam-Klages, Szczepanowski, Pollmann, Buck, Endl, Kruse, Rudolph, Parwaresch: repp86: A human protein associated in the progression of mitosis. in Molecular cancer research : MCR 2003 (PubMed)
    Show all 5 references for ABIN357426

  3. Human Polyclonal TPX2 Primary Antibody for WB - ABIN658474 : Bibby, Tang, Faisal, Drosopoulos, Lubbe, Houlston, Bayliss, Linardopoulos: A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2. in The Journal of biological chemistry 2009 (PubMed)
    Show all 3 references for ABIN658474

  4. Cow (Bovine) Polyclonal TPX2 Primary Antibody for WB - ABIN2782527 : Szczepanowski, Adam-Klages, Kruse, Pollmann, Klapper, Parwaresch, Heidebrecht: Regulation of repp86 stability by human Siah2. in Biochemical and biophysical research communications 2007 (PubMed)

  5. Human Polyclonal TPX2 Primary Antibody for IHC, ELISA - ABIN1534193 : Manda, Kohno, Matsuno, Takenoshita, Kuwano, Yokota: Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display. in Genomics 1999 (PubMed)

More Antibodies against TPX2 Interaction Partners

Human TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) interaction partners

  1. MiR (show MLXIP Antibodies)-491 inhibits hepatocellular carcinoma cell proliferation, invasion and migration by downregulating the expression of TPX2.

  2. expression of both TPX2 and PD-L1 (show CD274 Antibodies) are associated with persistence/recurrence of cervical intraepithelial neoplasia after cervical conization

  3. the levels and distribution of TPX2 are likely to be determinants of when and where kinesin-5 acts in neurons.

  4. TPX2 was a target gene of miR (show MLXIP Antibodies)-491.

  5. Propose TPX2 and AURKA (show AURKA Antibodies) as novel co-regulators on the MYC (show MYC Antibodies) pathway in colorectal neoplasms.

  6. Aurora A (show AURKA Antibodies)-dependent TPX2 phosphorylation controls mitotic spindle length through regulating microtubule flux.

  7. These results indicated that TPX2 has an impact on tumor angiogenesis in pancreatic cancer.

  8. Data show that cytoskeleton associated protein 5 (chTOG (show CKAP5 Antibodies)) only weakly promotes importin (show KPNA4 Antibodies)-regulated microtubule nucleation, but acts synergistically with TPX2 protein.

  9. RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 (show XPO7 Antibodies) and TPX2 have roles in serous epithelial ovarian cancer

  10. a causative link between altered function of AURKA-HMMR-TPX2-TUBG1 and breast carcinogenesis in BRCA1/2 mutation carriers

Mouse (Murine) TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) interaction partners

  1. Study demonstrates that the Golgi resident protein GM130 (show GOLGA2 Antibodies) activates the spindle assembly factor TPX2 (show DAZL Antibodies) to nucleate microtubules around the Golgi and further captures them to couple mitotic membranes to the spindle.

  2. The findings indicated that Tpx2 (show DAZL Antibodies) is essential for maintaining genomic stability through its role in spindle regulation.

  3. Tpx2 (show DAZL Antibodies) redistributes from the nucleus to the apical process, and promotes nuclear migration during G2-phase by altering microtubule organization.

Pig (Porcine) TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) interaction partners

  1. observations explain the poleward accumulation of Eg5 (show KIF11 Antibodies) in early mitosis and its redistribution in anaphase. Inhibition of dynein blocked Eg5 (show KIF11 Antibodies) movement on microtubules, whereas depletion of the Eg5 (show KIF11 Antibodies)-binding protein TPX2 resulted in end-directed Eg5 (show KIF11 Antibodies) movement.

  2. Data suggest that poleward transport of TPX2, which requires dynein and Eg5, down-regulates its microtubule nucleating activity near kinetochores and links microtubules to dynein for incorporation into the spindle.

TPX2 Antigen Profile

Protein Summary

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity).

Gene names and symbols associated with TPX2

  • TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2) antibody
  • TPX2, microtubule-associated (TPX2) antibody
  • TPX2, microtubule-associated (Tpx2) antibody
  • TPX2, microtubule-associated protein homolog (Xenopus laevis) (Tpx2) antibody
  • 2610005B21Rik antibody
  • C20orf1 antibody
  • C20orf2 antibody
  • DIL-2 antibody
  • DIL2 antibody
  • FLS353 antibody
  • GD:C20orf1 antibody
  • HCA519 antibody
  • HCTP4 antibody
  • p100 antibody
  • REPP86 antibody
  • TPX2 antibody

Protein level used designations for TPX2

TPX2, microtubule-associated, homolog (Xenopus laevis) , targeting protein for Xklp2-like , TPX2, microtubule-associated protein homolog , TPX2, microtubule-associated, homolog , differentially expressed in cancerous and non-cancerous lung cells 2 , differentially expressed in lung cells , hepatocellular carcinoma-associated antigen 519 , preferentially expressed in colorectal cancer , protein fls353 , restricted expression proliferation associated protein 100 , restricted expression proliferation-associated protein 100 , targeting protein for Xklp2

GENE ID SPECIES
100053648 Equus caballus
712961 Macaca mulatta
100010953 Monodelphis domestica
100392169 Callithrix jacchus
100469500 Ailuropoda melanoleuca
100585181 Nomascus leucogenys
22974 Homo sapiens
311546 Rattus norvegicus
72119 Mus musculus
477186 Canis lupus familiaris
507226 Bos taurus
100524467 Sus scrofa
Selected quality suppliers for anti-TPX2 (TPX2) Antibodies
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