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anti-TPX2, Microtubule-Associated Protein Homolog (Xenopus Laevis) (TPX2) Antibodies

The protein encoded by TPX2 is an RNA-binding nuclear protein that is a tumor-rejection antigen.

list all antibodies Gene Name GeneID UniProt
TPX2 9733 Q15020
TPX2 72119 A2APB8
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Top anti-TPX2 Antibodies at antibodies-online.com

Showing 6 out of 11 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB The anti-p100 Pab (ABIN388785) is used in Western blot to detect p100 in placenta lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB Western analysis of extracts from Jurkat cells using P100 antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 11 to 16 Days
$694.57
Details
Human Rabbit Un-conjugated   100 μL Log in to see 9 to 19 Days
$322.58
Details
Human Mouse Un-conjugated   100 μL Log in to see 9 to 19 Days
$322.58
Details

TPX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,
,
Mouse (Murine)


Top referenced anti-TPX2 Antibodies

  1. Human Monoclonal TPX2 Primary Antibody for WB - ABIN387763 : Olson, Wang, Pankratz, Fredericksen, Vachon, Vierkant, Cerhan, Couch: Centrosome-related genes, genetic variation, and risk of breast cancer. in Breast cancer research and treatment 2010 (PubMed)
    Show all 5 references for ABIN387763

  2. Human Polyclonal TPX2 Primary Antibody for IHC (p), WB - ABIN388785 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 3 references for ABIN388785

More Antibodies against TPX2 Interaction Partners

Human TPX2, Microtubule-Associated Protein Homolog (Xenopus Laevis) (TPX2) interaction partners

  1. miR (show MLXIP Antibodies)-124 regulates Tip110 expression and differentiation of human cord blood CD34 (show CD34 Antibodies)(+) cells

  2. Hypoxia led to Tip110 protein degradation through the ubiquitin-proteasome system. Under hypoxia, Tip110 stabilized p53 (show TP53 Antibodies), which in return destabilized Tip110.

  3. SART3 (show SART3 Antibodies) recruits ubH2B, which may be evicted from DNA during transcription, for deubiquitination by Usp15 (show USP15 Antibodies)

  4. YB-1 (show YBX1 Antibodies) potentiates the Tip110/Tat (show TAT Antibodies)-mediated transactivation of the HIV-1 LTR promoter.

  5. findings show C-MYC (show MYC Antibodies) upregulates transcription of TIP110 through interaction with the TIP110 E-box in the TIP110 promoter, ensuring high-level Tip110 expression in proliferating embryonic stem cells (hESCs); further show TIP110 regulates OCT4 (show POU5F1 Antibodies) alternative splicing in hESCs

  6. TIP110 is also expressed in human embryonic stem cells (hESCs) and expression was decreased with differentiation of these ESCs (show NR2E3 Antibodies).

  7. Results suggest that U4 and U6 small nuclear ribonucleoproteins (snRNPs) accumulate in Cajal bodies for the purpose of assembly into U4/U6 snRNPs by SART3/p110 (show SART3 Antibodies).

  8. involvement of U6-p110 (SART3 (show SART3 Antibodies)) in recycling of the U4atac/U6atac snRNP (show LSM2 Antibodies)

  9. Data suggest a model whereby p110 (SART3 (show SART3 Antibodies)) brings together U4 and U6 snRNAs through both RNA-protein and protein-protein interactions.

  10. Both purified and recombinant LSm2 (show LSM2 Antibodies)-8 proteins are able to recruit p110 (show CUX1 Antibodies) protein to U6 snRNA via interaction with the highly conserved C-terminal region of p110 (show CUX1 Antibodies).

Mouse (Murine) TPX2, Microtubule-Associated Protein Homolog (Xenopus Laevis) (TPX2) interaction partners

  1. Study demonstrates that the Golgi resident protein GM130 (show GOLGA2 Antibodies) activates the spindle assembly factor TPX2 (show DAZL Antibodies) to nucleate microtubules around the Golgi and further captures them to couple mitotic membranes to the spindle.

  2. The findings indicated that Tpx2 (show DAZL Antibodies) is essential for maintaining genomic stability through its role in spindle regulation.

  3. Tpx2 (show DAZL Antibodies) redistributes from the nucleus to the apical process, and promotes nuclear migration during G2-phase by altering microtubule organization.

TPX2 Antigen Profile

Protein Summary

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

Gene names and symbols associated with TPX2

  • squamous cell carcinoma antigen recognized by T cells 3 (SART3) antibody
  • TPX2, microtubule-associated protein homolog (Xenopus laevis) (Tpx2) antibody
  • 2610005B21Rik antibody
  • DIL2 antibody
  • DSAP1 antibody
  • p100 antibody
  • p110 antibody
  • p110(nrb) antibody
  • REPP86 antibody
  • RP11-13G14 antibody
  • TIP110 antibody

Protein level used designations for TPX2

SART-3 , hSART-3 , squamous cell carcinoma antigen recognized by T-cells 3 , tat-interacting protein of 110 kDa , targeting protein for Xklp2

GENE ID SPECIES
9733 Homo sapiens
72119 Mus musculus
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