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TIFAB associates with TIFA (MIM 609028) and inhibits TIFA-mediated activation of NF-kappa-B (NFKB1\; MIM 164011) (Matsumura et al., 2004 [PubMed 15047173]).[supplied by OMIM, Mar 2009].. Additionally we are shipping TRAF-Interacting Protein with Forkhead-Associated Domain, Family Member B Antibodies (19) and many more products for this protein.
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TIFAB loss increases TRAF6 (show TRAF6 Proteins) protein and the dynamic range of TLR4 (show TLR4 Proteins) signaling
study shows TIFAB is mainly expressed in B cells rather than T cells in the spleen; results suggest TIFAB could act as a negative regulator of TRAF6 (show TRAF6 Proteins)-induced cellular function such as B cell proliferation and maturation of dendritic cellss & macrophages
TIFAB associates with TIFA (MIM 609028) and inhibits TIFA-mediated activation of NF-kappa-B (NFKB1\; MIM 164011) (Matsumura et al., 2004
TRAF-interacting protein with forkhead-associated domain, family member B
, TIFA-like protein
, TIFA-related protein TIFAB
, TRAF-interacting protein with FHA domain-containing protein B
, TIFA like protein
, TIFA related protein TIFAB