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anti-TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) Antibodies

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Additionally we are shipping TIFA Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIFA 92610 Q96CG3
Anti-Mouse TIFA TIFA 211550 Q793I8
Anti-Rat TIFA TIFA 310877 Q5XIB9
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Top anti-TIFA Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TIFA Antibody (N-term) in CEM cell line lysates (35 µg/lane). TIFA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of TIFA Antibody (N-term) (ABIN653538) in CEM cell line lysates (35 µg/lane). TIFA (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

TIFA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , , , , , , , , , , ,

Top referenced anti-TIFA Antibodies

  1. Human Polyclonal TIFA Primary Antibody for EIA, WB - ABIN955209 : Minoda, Saeki, Aki, Takaki, Sanada, Koga, Kobayashi, Takaesu, Yoshimura: A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling. in Biochemical and biophysical research communications 2006 (PubMed)
    Show all 4 references for ABIN955209

More Antibodies against TIFA Interaction Partners

Human TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. This study reports the crystal structures of TIFA (show IL22 Antibodies) (residues 1-150, with the unstructured C-terminal tail truncated) and its complex with the N-terminal phosphothreonine9 peptide (residues 1-15).

  2. an innate immune signaling axis, mediated by phosphorylation-dependent oligomerization of the TRAF-interacting protein with forkhead-associated domain (TIFA) that is triggered by heptose-1,7-bisphosphate.

  3. identify a novel threonine phosphorylation site on TIFA (show IL22 Antibodies) and show that this phosphorylated threonine binds with the FHA (show CRY2 Antibodies) domain of TIFA (show IL22 Antibodies), leading to TIFA (show IL22 Antibodies) oligomerization and TIFA (show IL22 Antibodies)-mediated NF-kappaB (show NFKB1 Antibodies) activation

  4. TIFA (show IL22 Antibodies) induces the oligomerization and polyubiquitination of TRAF6 (show TRAF6 Antibodies), which leads to the activation of TAK1 (show MAP3K7 Antibodies) and IKK (show CHUK Antibodies) through a proteasome-independent mechanism

Mouse (Murine) TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. The increase in TIFA level appears to be a feed-forward mechanism involved in TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)-dependent signaling, leading to NF-kappaB (show NFKB1 Antibodies) activation and HMGB1 (show HMGB1 Antibodies) release

  2. TIFA is likely to mediate IRAK-1 (show IRAK1 Antibodies)/TRAF6 (show TRAF6 Antibodies) interaction upon IL-1 (show IL1A Antibodies) stimulation

  3. We propose that ZCCHC11 (show ZCCHC11 Antibodies) is a unique TLR signal regulator, which interacts with TIFA after LPS (show TLR4 Antibodies) treatment and suppresses the TRAF6 (show TRAF6 Antibodies)-dependent activation of NF-kappaB (show NFKB1 Antibodies).

TIFA Antigen Profile

Protein Summary

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (By similarity).

Gene names and symbols associated with TIFA

  • TRAF-interacting protein with forkhead-associated domain (TIFA) antibody
  • TRAF-interacting protein with forkhead-associated domain (tifa) antibody
  • TRAF-interacting protein with forkhead-associated domain (Tifa) antibody
  • Ab2-389 antibody
  • T2bp antibody
  • T6BP antibody
  • TIFA antibody
  • TIFAA antibody
  • xtifa antibody

Protein level used designations for TIFA

TRAF-interacting protein with forkhead-associated domain , TRAF-interacting protein with a forkhead-associated domain , TRAF-interacting protein with FHA domain-containing protein A , TRAF6-binding protein , TRAF2 binding protein , TRAF2-binding protein , TRAF6 binding protein , putative MAPK-activating protein PM14 , putative NF-kappa-B-activating protein 20 , Traf2 binding protein

GENE ID SPECIES
422692 Gallus gallus
471278 Pan troglodytes
487905 Canis lupus familiaris
100216213 Xenopus (Silurana) tropicalis
92610 Homo sapiens
211550 Mus musculus
310877 Rattus norvegicus
783855 Bos taurus
734184 Xenopus laevis
Selected quality suppliers for anti-TIFA (TIFA) Antibodies
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