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anti-TRAF2 and NCK Interacting Kinase (TNIK) Antibodies

Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function (Fu et al., 1999 [PubMed 10521462]).[supplied by OMIM, Mar 2008].. Additionally we are shipping TNIK Proteins (5) and TNIK Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNIK 23043 Q9UKE5
TNIK 665113 P83510
TNIK 294917  
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Top anti-TNIK Antibodies at antibodies-online.com

Showing 10 out of 159 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated DB, IHC (p) Dot blot analysis of Phospho-TNIK-pS764 Pab (ABIN389674) and TNIK-pS764 Pab (ABIN392501)on nitrocellulose membrane.  50 ng of Phospho-peptide (BP3276a) or Non Phospho-peptide (BP7970d) per dot were adsorbed. Antobodies working concentration was 0.5 µg/mL. P-Pab: phosphorylated antibody. NP-Pab: non-phophorylated antibody. P-Pep: phospho-peptide. NP-Pep: non-phospho-peptide. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-TNIK Pab (ABIN392499) is used in Western blot to detect TNIK in mouse brain tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of TNIK of 293 HEK lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of TNIK. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated DB Dot blot analysis of Phospho-TNIK-pS764 Pab (ABIN389674) and TNIK-pS764 Pab (ABIN392501)on nitrocellulose membrane.  50 ng of Phospho-peptide (BP3276a) or Non Phospho-peptide (BP7970d) per dot were adsorbed. Antobodies working concentration was 0.5 µg/mL. P-Pab: phosphorylated antibody. NP-Pab: non-phophorylated antibody. P-Pep: phospho-peptide. NP-Pep: non-phospho-peptide. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of TNIK expression in transfected 293T cell line by TNIK monoclonal antibody (M03), clone 3D4.Lane 1: TNIK transfected lysate(60.3 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged TNIK is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-TNIK antibody  ABIN1049422 IHC staining of human skeletal muscle, myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (p) Anti-TNIK antibody  ABIN1049421 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details

TNIK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TNIK Antibodies

  1. Human Polyclonal TNIK Primary Antibody for EIA, IHC (p) - ABIN358244 : Taira, Umikawa, Takei, Myagmar, Shinzato, Machida, Uezato, Nonaka, Kariya: The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton. in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for ABIN358244

  2. Human Polyclonal TNIK Primary Antibody for IHC (p), WB - ABIN392499 : Wang, Charych, Pulito, Lee, Graziane, Crozier, Revilla-Sanchez, Kelly, Dunlop, Murdoch, Taylor, Xie, Pausch, Hayashi-Takagi, Ishizuka, Seshadri, Bates, Kariya, Sawa, Weinberg, Moss, Houslay, Yan et al.: The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. ... in Molecular psychiatry 2011 (PubMed)
    Show all 2 references for ABIN392499

  3. Human Monoclonal TNIK Primary Antibody for ELISA, WB - ABIN564994 : Mahmoudi, Li, Ng, Taouatas, Vries, Mohammed, Heck, Clevers: The kinase TNIK is an essential activator of Wnt target genes. in The EMBO journal 2009 (PubMed)

  4. Human Monoclonal TNIK Primary Antibody for IF, WB - ABIN968788 : Fu, Shen, Huang, Lasaga, Payan, Luo: TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton. in The Journal of biological chemistry 1999 (PubMed)

  5. Human Polyclonal TNIK Primary Antibody for EIA, IHC (p) - ABIN360387 : Cantrell: Phosphoinositide 3-kinase signalling pathways. in Journal of cell science 2001 (PubMed)

More Antibodies against TNIK Interaction Partners

Human TRAF2 and NCK Interacting Kinase (TNIK) interaction partners

  1. High expression of TNIK in colorectal cancer was associated with recurrence in stage II and III colorectal cancer patients.

  2. Endogenous substrates of TNIK were identified in neurons, along with consensus sequences for TNIK.

  3. nuclear p-TNIK expression was studied in hepatocellular carcinoma, and p-TNIK nuclear expression was associated with poor prognosis and is a candidate prognostic marker for hepatocellular carcinoma

  4. Dynamic change of TNIK offers a way to protect cells from outside stimulus.

  5. TNIK mediates proliferation and survival of EBV-transformed B-cells.

  6. TNIK is essential for the activation of both the canonical Wnt (show WNT2 Antibodies) pathway and the JNK (show MAPK8 Antibodies) pathway, and serves as a pro-survival factor.

  7. TNIK is a specific effector of Rap2 to regulate actin cytoskeleton

Mouse (Murine) TRAF2 and NCK Interacting Kinase (TNIK) interaction partners

  1. This study demonstrate here that TNIK is expressed in neurons throughout the adult mouse brain.

  2. TNiK is required for dentate gyrus neurogenesis & for pattern separation in a 2-choice spatial discrimination task & for glutamate (show GRIN1 Antibodies)-dependent object-location paired associate learning.

  3. TNIK maintains levels of glutamate receptors and other key postsynaptic density (PSD) proteins at the synapse, with loss of TNIK protein or inhibition of TNIK activity causing rapid degradation of PSD constituents.

  4. siRNA depletion of TNIK followed by expression array analysis showed that TNIK is an essential, specific activator of Wnt (show WNT2 Antibodies) transcriptional programme.

TNIK Antigen Profile

Protein Summary

Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function (Fu et al., 1999

Gene names and symbols associated with TNIK

  • TRAF2 and NCK interacting kinase (TNIK) antibody
  • TRAF2 and NCK interacting kinase (Tnik) antibody
  • 1500031A17Rik antibody
  • 4831440I19Rik antibody
  • AI451411 antibody
  • C530008O15Rik antibody
  • C630040K21Rik antibody
  • RGD1561817 antibody
  • TNIK antibody

Protein level used designations for TNIK

TRAF2 and NCK interacting kinase , TRAF2 and NCK-interacting protein kinase-like , TRAF2 and NCK-interacting protein kinase , traf2 and NCK-interacting protein kinase , Traf2 and NCK interacting kinase

GENE ID SPECIES
100057722 Equus caballus
460849 Pan troglodytes
695414 Macaca mulatta
100437732 Pongo abelii
100603481 Nomascus leucogenys
23043 Homo sapiens
665113 Mus musculus
488166 Canis lupus familiaris
100233204 Sus scrofa
539627 Bos taurus
294917 Rattus norvegicus
424987 Gallus gallus
Selected quality suppliers for anti-TNIK (TNIK) Antibodies
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