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TRAF3 Interacting Protein 2 (TRAF3IP2) ELISA Kits

TRAF3IP2 encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. Additionally we are shipping TRAF3IP2 Antibodies (131) and TRAF3IP2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat TRAF3IP2 TRAF3IP2 361857  
Anti-Human TRAF3IP2 TRAF3IP2 10758 O43734
Anti-Mouse TRAF3IP2 TRAF3IP2 103213  
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More ELISA Kits for TRAF3IP2 Interaction Partners

Human TRAF3 Interacting Protein 2 (TRAF3IP2) interaction partners

  1. the first report to describe a non-adaptor function of Act1 by directly binding to the promoter region of IL-17A (show IL17A ELISA Kits) responsive genes and directly regulate their transcription.

  2. ACT1 is an essential adaptor molecule of Il-17 (show IL17A ELISA Kits)-induced expression of inflammation-related gene targets.

  3. Both the ACT-1 assay and the MAdCAM-1 (show MADCAM1 ELISA Kits) assay demonstrated acceptable reproducibility and repeatability. The assays were sufficiently stable to allow for clinical use. During clinical testing the assays demonstrated that vedolizumab was able to saturate peripheral cells at all doses tested.

  4. A G/G genotype of rs766748 in IL-17F (show IL17F ELISA Kits), and a C/C or C/A genotype of rs1883136 in TRAF3IP2.

  5. The suppressive effects of miR (show MLXIP ELISA Kits)-30a were mediated by directly targeting Traf3ip2 mRNA

  6. TRAF3IP2 may play a causal role in aldosterone-induced adverse cardiac remodeling in vivo.

  7. Single nucleotide polymorphisms in RBPJ (show RBPJ ELISA Kits), IL1R1 (show IL1RN ELISA Kits), REV3L, TRAF3IP2, IRF1 (show IRF1 ELISA Kits) and ICOS (show CTLA4 ELISA Kits) showed association with rheumatoid arthritis in black South Africans.

  8. A variant (rs76228616 SNP) in TRAF3IP2 gene could be involved in susceptibility to Steven-Johnson Syndrome.

  9. identify Syk (show SYK ELISA Kits) as an upstream signaling molecule in IL-17A (show IL17A ELISA Kits)-induced Act1-TRAF6 (show TRAF6 ELISA Kits) interaction in keratinocytes, and inhibition of Syk (show SYK ELISA Kits) can attenuate CCL20 (show CCL20 ELISA Kits) production

  10. These results indicate that oxLDL-induced endothelial cell death and dysfunction are mediated via TRAF3IP2 and that native HDL3 and the AMPK (show PRKAA1 ELISA Kits) activators inhibit this response.

Mouse (Murine) TRAF3 Interacting Protein 2 (TRAF3IP2) interaction partners

  1. using massively parallel reporter assays, we dissect the enhancer activity of three liver eExons (SORL1 (show SORL1 ELISA Kits) exon 17, TRAF3IP2 exon 2, PPARG (show PPARG ELISA Kits) exon 6) at single nucleotide resolution in the mouse liver

  2. TRAF3IP2 is a critical intermediate in IL-18 (show IL18 ELISA Kits)-induced cardiac fibroblast migration and differentiation in vitro.

  3. Our results support the important role of Act1 in the regulation of self-reactive B cells and reveal how Act1 functions to prevent the production of autoantibodies.

  4. These results demonstrate for the first time that AOPPs induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent

  5. CIKS knockdown inhibited high glucose-induced IKKbeta (show IKBKB ELISA Kits) and JNK (show MAPK8 ELISA Kits) phosphorylation, p65 (show NFkBP65 ELISA Kits) and c-Jun (show JUN ELISA Kits) nuclear translocation, and NF-kappaB (show NFKB1 ELISA Kits)- and AP-1 (show JUN ELISA Kits)-dependent proinflammatory cytokine, chemokine (show CCL1 ELISA Kits), and adhesion molecule (show NCAM1 ELISA Kits) expression.

  6. The findings define a new role for the IKK-related kinases in suppressing IL-17-mediated NF-kappaB activation through TRAF6-dependent Act1 phosphorylation.

  7. Data show that deletion of the CC' loop from Act1 or IL-17RA (show IL17RA ELISA Kits) abolished the interaction between both proteins.

  8. our findings indicate that Act1 expression in T cells is required for cellular and humoral Th2-mediated allergic responses and the development of airway hyperresponsiveness

  9. IL-17 (show IL17A ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) activation via CIKS/Act1: physiologic significance and signaling mechanisms.

  10. Study demonstrates that the TRAF3IP2 protein plays an important role in AD and suggests the protein as a therapeutic target to treat AD.

TRAF3IP2 Antigen Profile

Antigen Summary

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Gene names and symbols associated with TRAF3IP2

  • Traf3 interacting protein 2 (Traf3ip2) antibody
  • TRAF3 interacting protein 2 (TRAF3IP2) antibody
  • adapter protein CIKS-like (LOC100467029) antibody
  • adapter protein CIKS-like (LOC100480036) antibody
  • adapter protein CIKS-like (LOC100490063) antibody
  • TRAF3 interacting protein 2 (traf3ip3) antibody
  • TRAF3 interacting protein 2 (LOC100226375) antibody
  • TRAF3 interacting protein 2 (Traf3ip2) antibody
  • Act1 antibody
  • AI429613 antibody
  • C6orf2 antibody
  • C6orf4 antibody
  • C6orf5 antibody
  • C6orf6 antibody
  • CIKS antibody
  • MGC134034 antibody
  • PSORS13 antibody
  • RGD1304768 antibody
  • t3jam antibody
  • TRAF3IP2 antibody

Protein level used designations for TRAF3IP2

adapter protein CIKS , TRAF3 interacting protein 2 , adapter protein CIKS-like , NFkB-activating protein ACT1 , connection to IKK and SAPK/JNK , nuclear factor NF-kappa-B activator 1

361857 Rattus norvegicus
100390719 Callithrix jacchus
100439347 Pongo abelii
100467029 Ailuropoda melanoleuca
100473939 Ailuropoda melanoleuca
100480036 Ailuropoda melanoleuca
100490063 Xenopus (Silurana) tropicalis
421752 Gallus gallus
494853 Xenopus laevis
549319 Xenopus (Silurana) tropicalis
616801 Bos taurus
697530 Macaca mulatta
741209 Pan troglodytes
100226375 Taeniopygia guttata
10758 Homo sapiens
103213 Mus musculus
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