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RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. Additionally we are shipping TROVE2 Proteins (19) and TROVE2 Kits (1) and many more products for this protein.
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Dog (Canine) Polyclonal TROVE2 Primary Antibody for IHC, WB - ABIN2778905
Hennig, Ottosson, Andrésen, Horvath, Kuchroo, Broo, Wahren-Herlenius, Sunnerhagen: Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52. in The Journal of biological chemistry 2005
These findings establish a link among the lupus autoantigen Ro60, Alu retroelements, and type I interferon (show IFNA Antibodies).
Findings indicate a relentless turnover of short-lived clonotypic variants, masquerading as long-lived Ro60 humoral autoimmunity.
The Y3 RNA moiety of the Ro60 ribonucleoprotein plays a critical role in the pathogenesis of fetal cardiac injury by altering the subcellular location of Ro60 autoantibodies.
these data indicate that ZBP1 (show IGF2BP1 Antibodies) may function as an adapter to export the Ro/Y3 RNA complex from nuclei.
conclude that RNPs containing hY RNAs and Ro60, La or nucleolin (show NCL Antibodies) are not required for the function of hY RNAs in chromosomal DNA replication in a human cell-free system, which can be mediated by Y RNAs outside of these RNPs
dichotomy of human autoantibody responses against mutually exclusive determinants linked to a single domain of a systemic autoantigen and supports a model in which tolerance is broken by different immunogenic forms of Ro 60
Activation of Toll (show TLR4 Antibodies)-like receptors by fetal factor Ro60-associated single-stranded RNA particles is relevant in autoimmune-associated congenital heart block, where the obligate maternal factor (show ZAR1 Antibodies) is an anti-SSA/Ro autoantibody.
In viitro RNA chaperone activity of SSA2 was studied.
The structural organization and Zn2+-dependent subdomain interactions involving autoiantigenic epitopes in the RBBC region of SS-A (show TRIM21 Antibodies) were studied.
Increased Ro/SSA 60 and La/SSB mRNA expression in minor salivary glands in primary Sjogren's syndrome (pSS) suggest that these 2 autoantigens, but not Ro/SSA 52, are involved in tissue-specific autoimmune response in pSS.
Restricted specificity of intermolecular spreading to endogenous La (SS-B) and 60 kDa Ro (SS-A) in experimental autoimmunity.
RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.
TROVE domain family, member 2
, 60kD Ro/SSA autoantigen
, 60 kDa SS-A/Ro ribonucleoprotein-like
, 60 kDa Ro protein
, 60 kDa SS-A/Ro ribonucleoprotein
, 60 kDa ribonucleoprotein Ro
, Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)
, Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro)
, gastric cancer multi-drug resistance protein
, sjoegren syndrome type A antigen
, Sjogren syndrome antigen A2