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TSC22 Domain Family, Member 1 Proteins (TSC22D1)

TSC22D1 encodes a member of the TSC22 domain family of leucine zipper transcription factors. Additionally we are shipping TSC22 Domain Family, Member 1 Antibodies (72) and TSC22 Domain Family, Member 1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TSC22D1 8848 Q15714
TSC22D1 21807 P62500
Rat TSC22D1 TSC22D1 498545 P62501
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Top TSC22 Domain Family, Member 1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details

TSC22D1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced TSC22 Domain Family, Member 1 Proteins

  1. Human TSC22D1 Protein expressed in Escherichia coli (E. coli) - ABIN2005311 : Kester, Blanchetot, den Hertog, van der Saag, van der Burg: Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN2005311

  2. Mouse (Murine) TSC22D1 Protein expressed in Escherichia coli (E. coli) - ABIN2008747 : Mendonça, Koles, Doi, Sellitti: Transforming growth factor-beta1 regulation of C-type natriuretic peptide expression in human vascular smooth muscle cells: dependence on TSC22D1. in American journal of physiology. Heart and circulatory physiology 2010 (PubMed)
    Show all 3 references for ABIN2008747

More Proteins for TSC22 Domain Family, Member 1 (TSC22D1) Interaction Partners

Human TSC22 Domain Family, Member 1 (TSC22D1) interaction partners

  1. TSC-22 acts as a tumor suppressor by safeguarding p53 (show TP53 Proteins) from poly-ubiquitination mediated-degradation.

  2. we report that induced Tsc-22 leads to enhancement of TGF-beta (show TGFB1 Proteins)-dependent signaling and enhancement is blocked by expression of a dominant-negative Tsc-22 mutant

  3. Differential regulation of antagonistic TSC22D1 variants is required for the establishment of oncogene (show RAB1A Proteins)-induced cellular senescence.

  4. Results support role of TSC22D1 as an enhancer of CNP (show CNP Proteins) transcription and suggest that TGF-beta (show TGFB1 Proteins)-induced upregulation of CNP (show CNP Proteins) expression in smooth muscle may be mediated in part by increased transcription of TSC22D1.

  5. Leucine Zipper structure of TSC22 markedly inhibits the anchorage independent growth of salivary gland cancer cells

  6. TSC-22 is an important downstream component of PPARgamma (show PPARG Proteins) and TGF-beta (show TGFB1 Proteins) signaling during intestinal epithelial cell differentiation

  7. findings suggest that the TSC-22 gene (-396) A allele is associated with an increasing risk of diabetic nephropathy

  8. Upregulation of TSC-22 mRNA by TGF-beta 1 (show TGFB1 Proteins) is achieved by mRNA stabilization.

  9. Tsc-22 modulates the TGF-beta (show TGFB1 Proteins)-dependant signaling pathway and binds to and modulate the transcriptional activity of Smad3 (show SMAD3 Proteins) and Smad4 (show SMAD4 Proteins). It has effect on cellular differentiation

  10. expression of TSC-22 in prostate is restricted to basal layer; maybe useful marker for differentation between normal and malignant acinar epithelium of prostate

Mouse (Murine) TSC22 Domain Family, Member 1 (TSC22D1) interaction partners

  1. Fat4 and Tsc22d1 are likely candidate genes to influence formation of spontaneous pulmonary adenoma in aging male and female mice, respectively.

  2. post-transcriptional regulation of Tsc-22 mediated through Ybx1 (show YBX1 Proteins), a miR (show MLXIP Proteins)-216a target, plays a key role in TGF-beta (show TGFB1 Proteins)-induced Col1a2 (show COL1A2 Proteins) in MC related to the pathogenesis of diabetic nephropathy

  3. novel opposing functions of the two mammalian TSC (show SLC12A3 Proteins)-22D1 isoforms in cell survival and proliferation, and establish the TSC (show SLC12A3 Proteins)-22D1 isoform 2 as a potential regulator of cell death during mammary gland involution

  4. Analysis of the regulation of Tgf beta1i4 by Foxc1 (show FOXC1 Proteins) in mesenchymal cells isolated from the periocular region revealed that Foxc1 (show FOXC1 Proteins) negatively regulated Tgf beta1i4 expression, presumably via secreted factors such as TGF-beta1 (show TGFB1 Proteins).

  5. TSC-22 normally contributes to the regulation of hematopoietic stem cell function and is a putative tumor suppressor gene that is hypermethylated and silenced in T or NK LGL leukemia.

Xenopus laevis TSC22 Domain Family, Member 1 (TSC22D1) interaction partners

  1. XTSC-22 (TSC-22) is required for cell movement during gastrulation though cell cycle regulation.

  2. Analysis of deletion mutants of XTSC-22 revealed that nuclear localization of the N-terminal TSC (show TESC Proteins)-box is necessary for cell cycle inhibition by XTSC-22.

TSC22 Domain Family, Member 1 (TSC22D1) Protein Profile

Protein Summary

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with TSC22D1

  • zgc:65895 (zgc:65895)
  • TSC22 domain family, member 1 (TSC22D1)
  • TSC22 domain family protein 1 (tsc22d1)
  • TSC22 domain family, member 1 (Tsc22d1)
  • TSC22 domain family, member 1 (tsc22d1)
  • AA589566 protein
  • AW105905 protein
  • DKFZp459J163 protein
  • DKFZp459O033 protein
  • Egr5 protein
  • fj34d05 protein
  • MGC69210 protein
  • MGC186361 protein
  • Ptg-2 protein
  • Tgfb1i4 protein
  • TS22A protein
  • Tsc protein
  • TSC-22 protein
  • tsc22 protein
  • tsc22d1 protein
  • wu:fj34d05 protein
  • zgc:65869 protein
  • zgc:77475 protein
  • zgc:85857 protein

Protein level used designations for TSC22D1

TSC22 domain family protein 1 , transforming growth factor beta 1 induced transcript 4 , TSC22 domain family, member 1 , TGFB-stimulated clone 22 homolog , TGFbeta-stimulated clone 22 , cerebral protein 2 , regulatory protein TSC-22 , transcriptional regulator TSC-22 , transforming growth factor beta-1-induced transcript 4 protein , transforming growth factor beta-stimulated protein TSC-22 , Tgfb-stimulated clone 22 homolog , Tsc22-related inducible leucine zipper 1b , regulatory protein Tsc22 , Transforming growth factor beta stimulated clone 22 , TGFb stimulated clone 22 (TSC-22) , TSC22 domain family 1 , short tandem repeat locus PEZ20 variant 19

GENE ID SPECIES
393546 Danio rerio
452573 Pan troglodytes
594936 Xenopus (Silurana) tropicalis
100059678 Equus caballus
100173975 Pongo abelii
100173988 Pongo abelii
8848 Homo sapiens
21807 Mus musculus
498545 Rattus norvegicus
335842 Danio rerio
494732 Xenopus laevis
396005 Gallus gallus
476927 Canis lupus familiaris
100155900 Sus scrofa
510359 Bos taurus
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