anti-TSC22 Domain Family, Member 3 (TSC22D3) Antibodies

The protein encoded by TSC22D3 shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. Additionally we are shipping TSC22D3 Kits (18) and TSC22D3 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TSC22D3 1831 Q99576
TSC22D3 14605 Q9Z2S7
TSC22D3 83514 Q9EQZ1
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Top anti-TSC22D3 Antibodies at antibodies-online.com

Showing 10 out of 103 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB TSC22D3 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35 µg/lane). This demonstrates the TSC22D3 antibody detected the TSC22D3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$340.00
Details
Human Rabbit Un-conjugated WB TSC22D3 Antibody (Center)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TSC22D3 antibody detected the TSC22D3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TSC22D3 is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (34.21 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated IF, WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TSC22D3 on formalin-fixed paraffin-embedded human lymph node (antibody concentration 3 µg/mL).  Detection limit for recombinant GST tagged TSC22D3 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of GILZ staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$511.50
Details

TSC22D3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TSC22D3 Antibodies

  1. Human Polyclonal TSC22D3 Primary Antibody for EIA, WB - ABIN955352 : Latré de Laté, Pépin, Assaf-Vandecasteele, Espinasse, Nicolas, Asselin-Labat, Bertoglio, Pallardy, Biola-Vidamment: Glucocorticoid-induced leucine zipper (GILZ) promotes the nuclear exclusion of FOXO3 in a Crm1-dependent manner. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for 955352

  2. Human Monoclonal TSC22D3 Primary Antibody for ELISA, WB - ABIN515084 : Srinivasan, Janardhanam: Novel p65 binding glucocorticoid-induced leucine zipper peptide suppresses experimental autoimmune encephalomyelitis. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against TSC22D3 Interaction Partners

Zebrafish TSC22 Domain Family, Member 3 (TSC22D3) interaction partners

  1. Zebrafish tsc22d3 is a ventralizing gene and plays a role in early embryogenesis

Human TSC22 Domain Family, Member 3 (TSC22D3) interaction partners

  1. TSC22D3 gene expression is significantly associated with long-term changes in Blood Pressure, providing a link between gene expression and Blood Pressure.

  2. Overall, these results suggest that GILZ antagonizes the pro-inflammatory effects of TNFa (show TNF Antibodies) in human adipocytes, and its downregulation in obesity may contribute to adipose inflammation and dysregulated adipokine production, and thereby systemic metabolism.

  3. Under endoplasmic reticulum stress conditions, overexpression of GILZ significantly reduced activation of mitochondrial pathway of apoptosis by maintaining Bcl-xl (show BCL2L1 Antibodies) level. GILZ protein affects the unfolded protein response signaling shifting the balance towards pro-survival signals as judged by down-regulation of CHOP (show DDIT3 Antibodies), ATF4 (show ATF4 Antibodies), XBP1s mRNA and increase in GRP78 (show HSPA5 Antibodies) protein level.

  4. results reveal GILZ to be a new actor in apoptosis regulation in neutrophil-like cells involving JNK (show MAPK8 Antibodies) and Mcl-1 (show MCL1 Antibodies).

  5. GILZ is a non-redundant regulator of B cell activity, with important potential clinical implications in systemic lupus erythematosus.

  6. our data suggest that GILZ is a key regulator of macrophage functions.

  7. L-GILZ stabilizes p53 (show TP53 Antibodies) proteins by decreasing p53 (show TP53 Antibodies) ubiquitination and increasing MDM2 (show MDM2 Antibodies) ubiquitination.

  8. The N-terminal part of L-GILZ protein is responsible for Ras/L-GILZ protein-to-protein interaction, important for the control of proliferation rate of spermatogonia.

  9. PUVA directly stimulates GILZ expression.

  10. Data show a diminished expression of the anti-inflammatory mediator GILZ in the inflamed vasculature and indicate that GILZ downregulation requires the mRNA binding protein ZFP36 (show ZFP36 Antibodies).

Mouse (Murine) TSC22 Domain Family, Member 3 (TSC22D3) interaction partners

  1. GILZ promotes potassium secretion by inhibiting sodium-chloride cotransporter (show SLC12A3 Antibodies) and enhancing distal sodium delivery to the epithelial sodium channel.

  2. HuR (show ELAVL1 Antibodies) overexpression led to increased GILZ protein levels but had no effect on GILZ mRNA expression.

  3. The present findings shed light on the role of GILZ in the mechanism of induction of Anxa1 (show ANXA1 Antibodies) by GCs (show UGCG Antibodies). As Anxa1 (show ANXA1 Antibodies) is an important protein for the resolution of inflammatory response, GILZ may represent a new pharmacologic target for treatment of inflammatory diseases.

  4. Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss

  5. marked reduction in cardiac GILZ in association with increased Th-17 cells accompanied with marked disruption of mitochondrial membrane potential and increased apoptotic/necrotic cell death in hearts subjected to myocardial infarction

  6. results identify GILZ as an endogenous inhibitor of macropinocytosis in DCs, the action of which contributes to the fine-tuning of Ag cross-presentation.

  7. Obesity is associated with a downregulation of the Gr-Gilz axis in kupffer cells, which promotes liver inflammation.

  8. GILZ is a non-redundant regulator of B cell activity, with important potential clinical implications in systemic lupus erythematosus.

  9. Data show that glucocorticoid-induced leucine zipper (GILZ) maintains a threshold for activation of Th17 responses and interleukin 17 (IL-17 (show IL17A Antibodies))-dependent pathology.

  10. Lack of glucocorticoid-induced leucine zipper deregulates B-cell survival and results in B-cell lymphocytosis

TSC22D3 Antigen Profile

Protein Summary

The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with TSC22D3

  • TSC22 domain family, member 3 (tsc22d3) antibody
  • TSC22 domain family, member 3 (TSC22D3) antibody
  • TSC22 domain family, member 3 (LOC100227519) antibody
  • TSC22 domain family, member 3 (LOC100356656) antibody
  • TSC22 domain family, member 3 (Tsc22d3) antibody
  • DIP antibody
  • DSIP antibody
  • Dsip1 antibody
  • Dsipi antibody
  • Gilz antibody
  • hDIP antibody
  • MGC53285 antibody
  • Tilz3 antibody
  • TSC-22R antibody
  • TSC22D3 antibody
  • zgc:65831 antibody
  • zgc:77028 antibody

Protein level used designations for TSC22D3

TSC22 domain family, member 3 , glucocorticoid-induced leucine zipper , TSC22 domain family protein 3 , gilz , glucocorticoid-induced leucine zipper protein , DSIP-immunoreactive leucine zipper protein , DSIP-immunoreactive peptide , TSC-22 related protein , TSC-22-like protein , TSC-22-related protein , delta sleep inducing peptide, immunoreactor , delta sleep-inducing peptide immunoreactor , TSC22 domain family 3 , TSC22-related inducible leucine zipper 3 , TSC22-related-inducible leucine zipper 3 , long glucocorticoid-induced leucine zipper protein , DIP protein , Glucocorticoid-induced leucine zipper protein , delta-sleep-inducing peptide

GENE ID SPECIES
379978 Xenopus laevis
393541 Danio rerio
492057 Canis lupus familiaris
702656 Macaca mulatta
739684 Pan troglodytes
768091 Gallus gallus
100125309 Bos taurus
100145088 Xenopus (Silurana) tropicalis
100227519 Taeniopygia guttata
100356656 Oryctolagus cuniculus
1831 Homo sapiens
14605 Mus musculus
83514 Rattus norvegicus
100517321 Sus scrofa
100171736 Pongo abelii
Selected quality suppliers for anti-TSC22D3 (TSC22D3) Antibodies
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