You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) Antibodies

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Additionally we are shipping Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 Kits (9) and Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNKS2 80351 Q9H2K2
TNKS2 74493 Q3UES3
TNKS2 309512  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated FACS, WB Tnks 2 Antibody (C-term) (ABIN651506) western blot analysis in mouse testis tissue lysates (35 µg/lane). This demonstrates the Tnks 2 antibody detected Tnks 2 protein (arrow). Tnks 2 Antibody (C-term) (ABIN651506) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using Tankyrase 2, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2000. WB Image Sample (30 ug of whole cell lysate) A: A431 , B: Hela C: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Biotin FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$903.83
Details
Human Goat Un-conjugated WB   100 μg Log in to see 4 to 5 Days
$318.20
Details

TNKS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,

, , , , ,
Mouse (Murine)
,

Rat (Rattus)
,

Top referenced anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 Antibodies

  1. Dog (Canine) Polyclonal TNKS2 Primary Antibody for WB - ABIN401534 : Sidorova, Zavalishina, Kurchashova, Korsakova, Nazhimov, Frank, Kuimov: Immunohistochemical detection of tankyrase 2 in human breast tumors and normal renal tissue. in Cell and tissue research 2005 (PubMed)

More Antibodies against Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 Interaction Partners

Human Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) interaction partners

  1. Data show that E7449 represents a dual Poly(ADP-ribose) Polymerase 1 (show PARP1 Antibodies)/2 and tankyrase 1 (show TNKS Antibodies)/2 inhibitor which has the advantage of targeting Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling addicted tumors.

  2. Tankyrase inhibition is a potential therapeutic approach for treating a subgroup HCC (show FAM126A Antibodies) with aberrant WNT (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.

  3. TNKS2 is recruited to DNA lesions by MDC1 (show MDC1 Antibodies) and promotes homologous recombination in response to DNA double strand breaks.

  4. The variability of genes encoding for TERF1 (show TERF1 Antibodies) and TNKS2 is important for keeping the integrity of the telomere structure and show a significant association with longevity.

  5. Studies show a significant interaction of IWR1 with acidic and polar residues (Asp (show ASIP Antibodies) and Tyr (show TYR Antibodies)) in the hydrophobic region at the induced pocket of TNKS1 (show TNKS Antibodies)/TNKS2. These two residues are the key for the mechanism of inhibition of TNKS (show TNKS Antibodies) proteins.

  6. Data indicate a basis for development of flavones as tankyrase inhibitors and suggest the development of other structurally related inhibitors.

  7. Data suggest that miR (show MLXIP Antibodies)-20a can promote migration and invasion of cervical cancer cells through the upregulation of TNKS2.

  8. Study reports crystal structures of a representative ankyrin repeat clusters of TNKS2 bound to targeting peptides from six substrates.

  9. RNF146 (show RNF146 Antibodies) RING-type ubiquitin E3 ligase as a positive regulator of Wnt (show WNT2 Antibodies) signaling that operates with tankyrase to maintain low steady-state levels of Axin (show AXIN1 Antibodies) proteins

  10. TNKS2 bound to Epstein-Barr virus origin of plasmid replication in coimmunoprecipitation experiments with transfected cell lysates.

Mouse (Murine) Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) interaction partners

  1. TNKS2 is required in insulin (show INS Antibodies)-stimulated glucose disposal.

  2. Study shows that TNKS2, regulates 3BP2 stability through ADP-ribosylation and subsequent ubiquitylation in osteoclasts; cherubism mutations uncouple 3BP2 from Tankyrase-mediated protein destruction.

  3. Data show that Tnks1 (show TNKS Antibodies) and 2 are broadly expressed during mouse development and are essential during kidney and lung development. In the kidney, blockage of tankyrase activity phenocopies the effect of blocking production of all Wnt (show WNT2 Antibodies) ligands.

  4. inactivation of tankyrase 2 does not result in the alteration in telomere length when monitored through multiple generations of breeding, tankyrase 2 functions in potentially telomerase-independent pathways to affect overall development and/or metabolism.

  5. Tnks2 has a role in normal growth and development but is not essential for telomere length maintenance or telomere capping in mice.

  6. tankyrase 2is essential but redundant for mouse embryonic development

Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) Antigen Profile

Protein Summary

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles (By similarity).$.

Gene names and symbols associated with TNKS2

  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2) antibody
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (tnks2) antibody
  • tankyrase-2-like (LOC100855568) antibody
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (Tnks2) antibody
  • 5430432P15Rik antibody
  • AA517131 antibody
  • AI662480 antibody
  • ARTD6 antibody
  • PARP-5b antibody
  • PARP-5c antibody
  • PARP5B antibody
  • PARP5C antibody
  • pART6 antibody
  • Tank2 antibody
  • tankyrase-2 antibody
  • TNKL antibody
  • TNKS-2 antibody
  • TNKS2 antibody

Protein level used designations for TNKS2

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 , tankyrase-2 , tankyrase-2-like , ADP-ribosyltransferase diphtheria toxin-like 6 , TNKS-2 , TRF1-interacting ankyrin-related ADP-ribose polymerase 2 , poly [ADP-ribose] polymerase 5B , tankyrase 2 , tankyrase II , tankyrase-like protein , tankyrase-related protein

GENE ID SPECIES
477767 Canis lupus familiaris
533901 Bos taurus
698050 Macaca mulatta
100061968 Equus caballus
100391147 Callithrix jacchus
100539557 Meleagris gallopavo
100567928 Anolis carolinensis
100591011 Nomascus leucogenys
100855568 Canis lupus familiaris
80351 Homo sapiens
74493 Mus musculus
309512 Rattus norvegicus
100154520 Sus scrofa
374253 Gallus gallus
Selected quality suppliers for anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) Antibodies
Did you look for something else?