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Taspase, Threonine Aspartase, 1 (TASP1) ELISA Kits

TASP1 encodes an endopeptidase that cleaves specific substrates following aspartate residues. Additionally we are shipping Taspase, Threonine Aspartase, 1 Antibodies (38) and Taspase, Threonine Aspartase, 1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse TASP1 TASP1 75812 Q8R1G1
Anti-Rat TASP1 TASP1 311468  
Anti-Human TASP1 TASP1 55617 Q9H6P5
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More ELISA Kits for Taspase, Threonine Aspartase, 1 Interaction Partners

Mouse (Murine) Taspase, Threonine Aspartase, 1 (TASP1) interaction partners

  1. Taspase1 deficiency disrupts the expression of cyclins and proliferation of HER2 (show ERBB2 ELISA Kits)+ breast cancer cells.

  2. TFIIA (show GTF2A1 ELISA Kits) is the principal TASP1 substrate that orchestrates craniofacial morphogenesis.

  3. Taspase1 cleaves a ubiquitously expressed GTF (TFIIA (show GTF2A1 ELISA Kits)) to enable tissue-specific (testis) transcription, meeting the demand for sophisticated regulation of distinct subsets of genes in higher organisms.

  4. TASP1, EPS15R, and PRPF3 (show PRPF3 ELISA Kits) expression were significantly induced in HCCs (show HCCS ELISA Kits) of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha (show HNF4A ELISA Kits)

Human Taspase, Threonine Aspartase, 1 (TASP1) interaction partners

  1. simultaneous expression of the leukemogenic AF4-MLL (show MLL ELISA Kits) and dnTASP1 causes the disappearance of the leukemogenic oncoprotein, because the uncleaved AF4-MLL (show MLL ELISA Kits) protein (328 kDa) is subject to proteasomal degradation.

  2. Our results provide first evidence that Taspase1 processing affects TFIIA (show GTF2A1 ELISA Kits) regulation of TFIID (show TBP ELISA Kits) and suggest that Taspase1 processing of TFIIA (show GTF2A1 ELISA Kits) is required to establish INR (show INSR ELISA Kits)-selective core promoter activity in the presence of NC2 (show GTF2H5 ELISA Kits).

  3. Taspase1 appears to exploit the nuclear export activity of importin-alpha (show KPNA4 ELISA Kits)/nucleophosmin (show NPM1 ELISA Kits) to gain transient access to the cytoplasm required to also cleave its cytoplasmic substrates.

  4. Cell-based analysis of structure-function activity of threonine aspartase 1.

  5. purification and cloning of threonine aspartase 1 responsible for cleaving MLL (show MLL ELISA Kits); RNAi-mediated knockdown of Taspase1 results in the appearance of unprocessed MLL (show MLL ELISA Kits) and the loss of proper HOX (show MSH2 ELISA Kits) gene expression

  6. Transfected taspase 1 enhances cleavage of TFIIA (show GTF2A1 ELISA Kits), and RNA interference knockdown of endogenous taspase 1 diminishes cleavage of TFIIA (show GTF2A1 ELISA Kits) in vivo.

  7. TASP1, EPS15R, and PRPF3 (show PRPF3 ELISA Kits) expression were significantly induced in HCCs (show HCCS ELISA Kits) of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha (show HNF4A ELISA Kits)

Taspase, Threonine Aspartase, 1 (TASP1) Antigen Profile

Antigen Summary

This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with TASP1

  • taspase, threonine aspartase 1 (Tasp1) antibody
  • taspase, threonine aspartase, 1 (TASP1) antibody
  • 4930485D02Rik antibody
  • AW986064 antibody
  • C20orf13 antibody
  • dJ585I14.2 antibody
  • RGD1308591 antibody

Protein level used designations for TASP1

taspase-1 , threonine aspartase 1 , taspase 1

GENE ID SPECIES
75812 Mus musculus
311468 Rattus norvegicus
55617 Homo sapiens
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