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Taspase, Threonine Aspartase, 1 Proteins (TASP1)

TASP1 encodes an endopeptidase that cleaves specific substrates following aspartate residues. Additionally we are shipping Taspase, Threonine Aspartase, 1 Antibodies (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TASP1 75812 Q8R1G1
Rat TASP1 TASP1 311468  
TASP1 55617 Q9H6P5
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Top Taspase, Threonine Aspartase, 1 Proteins at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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TASP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Taspase, Threonine Aspartase, 1 (TASP1) Interaction Partners

Mouse (Murine) Taspase, Threonine Aspartase, 1 (TASP1) interaction partners

  1. Taspase1 deficiency disrupts the expression of cyclins and proliferation of HER2 (show ERBB2 Proteins)+ breast cancer cells.

  2. TFIIA (show GTF2A1 Proteins) is the principal TASP1 substrate that orchestrates craniofacial morphogenesis.

  3. Taspase1 cleaves a ubiquitously expressed GTF (TFIIA (show GTF2A1 Proteins)) to enable tissue-specific (testis) transcription, meeting the demand for sophisticated regulation of distinct subsets of genes in higher organisms.

  4. TASP1, EPS15R, and PRPF3 (show PRPF3 Proteins) expression were significantly induced in HCCs (show HCCS Proteins) of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha (show HNF4A Proteins)

Human Taspase, Threonine Aspartase, 1 (TASP1) interaction partners

  1. simultaneous expression of the leukemogenic AF4-MLL (show MLL Proteins) and dnTASP1 causes the disappearance of the leukemogenic oncoprotein, because the uncleaved AF4-MLL (show MLL Proteins) protein (328 kDa) is subject to proteasomal degradation.

  2. Our results provide first evidence that Taspase1 processing affects TFIIA (show GTF2A1 Proteins) regulation of TFIID (show TBP Proteins) and suggest that Taspase1 processing of TFIIA (show GTF2A1 Proteins) is required to establish INR (show INSR Proteins)-selective core promoter activity in the presence of NC2 (show GTF2H5 Proteins).

  3. Taspase1 appears to exploit the nuclear export activity of importin-alpha (show KPNA4 Proteins)/nucleophosmin (show NPM1 Proteins) to gain transient access to the cytoplasm required to also cleave its cytoplasmic substrates.

  4. Cell-based analysis of structure-function activity of threonine aspartase 1.

  5. purification and cloning of threonine aspartase 1 responsible for cleaving MLL (show MLL Proteins); RNAi-mediated knockdown of Taspase1 results in the appearance of unprocessed MLL (show MLL Proteins) and the loss of proper HOX (show MSH2 Proteins) gene expression

  6. Transfected taspase 1 enhances cleavage of TFIIA (show GTF2A1 Proteins), and RNA interference knockdown of endogenous taspase 1 diminishes cleavage of TFIIA (show GTF2A1 Proteins) in vivo.

  7. TASP1, EPS15R, and PRPF3 (show PRPF3 Proteins) expression were significantly induced in HCCs (show HCCS Proteins) of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha (show HNF4A Proteins)

Taspase, Threonine Aspartase, 1 (TASP1) Protein Profile

Protein Summary

This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with TASP1

  • taspase, threonine aspartase 1 (Tasp1)
  • taspase, threonine aspartase, 1 (TASP1)
  • 4930485D02Rik protein
  • AW986064 protein
  • C20orf13 protein
  • dJ585I14.2 protein
  • RGD1308591 protein

Protein level used designations for TASP1

taspase-1 , threonine aspartase 1 , taspase 1

GENE ID SPECIES
75812 Mus musculus
311468 Rattus norvegicus
55617 Homo sapiens
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