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Taste Receptor, Type 1, Member 1 Proteins (TAS1R1)

The protein encoded by TAS1R1 is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. Additionally we are shipping Taste Receptor, Type 1, Member 1 Antibodies (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TAS1R1 80835 Q7RTX1
TAS1R1 110326 Q99PG6
Rat TAS1R1 TAS1R1 29407 Q9Z0R8
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Top Taste Receptor, Type 1, Member 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TAS1R1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Taste Receptor, Type 1, Member 1 (TAS1R1) Interaction Partners

Zebrafish Taste Receptor, Type 1, Member 1 (TAS1R1) interaction partners

Human Taste Receptor, Type 1, Member 1 (TAS1R1) interaction partners

  1. The study provides human psychophysical evidence that TAS1R1 polymorphisms associate with modest differences in overall taste intensity, which were independent from other well-studied markers of variation in oral sensation.

  2. A complex molecular mechanism involving changes in the properties of both the orthosteric and non-orthosteric sites of T1R1 underlies the determination of ligand specificity in mammalian T1R1/T1R3 (show TAS1R3 Proteins).

  3. Data show that that Tas1r1 and Tas1r3 (show TAS1R3 Proteins) are expressed in murine and human spermatozoa.

  4. amino acid substitutions (A110V and R507Q) in the N-terminal ligand-binding domain of T1R1 severely impair receptor functions in vitro

  5. sequence diff (show TAS1R3 Proteins)erences in T1R receptors within and between species (human and mouse) can significantly influence the selectivity and specificity of taste responses

  6. findings demonstrate the different functional roles of T1R3 (show TAS1R3 Proteins) and T1R2 (show TAS1R2 Proteins) and the presence of multiple ligand binding sites on the sweet taste receptor

  7. Taken together, these results suggest that Tas1R1-Tas1R3 (show TAS1R3 Proteins) receptor variants found in human fungiform papillae might contribute to inter-individual differences of sensitivity to L-glutamate (show GRIN1 Proteins).

  8. In our sample of subjects, the frequencies of 2 nsSNPs, C329T in tas1r1 and C2269T in tas1r3 (show TAS1R3 Proteins), were significantly higher in [glutamate (show GRIN1 Proteins)] nontasters than expected, whereas G1114A in tas1r1 was more frequent in tasters.

Mouse (Murine) Taste Receptor, Type 1, Member 1 (TAS1R1) interaction partners

  1. T1R1/T1R3 have roles in regulating ERK1/2 and mTORC1 in MIN6 cells

  2. Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 (show GRM4 Proteins) knockout mice

  3. A complex molecular mechanism involving changes in the properties of both the orthosteric and non-orthosteric sites of T1R1 underlies the determination of ligand specificity in mammalian T1R1/T1R3 (show TAS1R3 Proteins).

  4. cell surface G protein coupled receptor (GPCR (show TAS1R3 Proteins)) TAS1R1-TAS1R3 (show TAS1R3 Proteins) (T1R1-T1R3 (show TAS1R3 Proteins)) can sense extracellular amino acids, activate MTORC1, and inhibit autophagy

  5. examined the function of umami taste receptor, which has a dimeric protein structure composed of Tas1r1 and Tas1r3 (show TAS1R3 Proteins), as an amino acid sensor

  6. Data show that that Tas1r1 and Tas1r3 (show TAS1R3 Proteins) are expressed in murine and human spermatozoa.

  7. Data sugget that heterodimer of Tas1R1 and Tas1R3 (show TAS1R3 Proteins) is the fundamental receptor for the sensing amino acids and regulates the amino acid-induced insulin (show INS Proteins) secretion in pancreatic beta-cells.

  8. T1R1 and T1R3 (show TAS1R3 Proteins) combine to function as a broadly tuned L-amino-acid sensor responding to most of the 20 standard amino acids, but not to their D-enantiomers or other compounds

  9. behavioral and physiological characterization of T1R1, T1R2 (show TAS1R2 Proteins), and T1R3 (show TAS1R3 Proteins) knockout mice

  10. These results suggested that in fungiform papillae, gustducin (show GNAT3 Proteins) might play a role in the sweet taste signal transduction cascade mediated by a sweet receptor based on the T1r2 (show TAS1R2 Proteins) and T1r3 (show TAS1R3 Proteins) combination, in fungiform papillae.

Taste Receptor, Type 1, Member 1 (TAS1R1) Protein Profile

Protein Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TAS1R1

  • taste receptor, type 1, member 1 (tas1r1)
  • taste receptor, type 1, member 1 (TAS1R1)
  • taste receptor, type 1, member 1 (Tas1r1)
  • Gpr70 protein
  • T1r1 protein
  • TR1 protein

Protein level used designations for TAS1R1

taste receptor type 1 member 1 , zfT1R1 , sweet taste receptor T1r , taste receptor, type 1, member 1 , taste receptor type 1 member 1-like , G protein-coupled receptor 70 , G-protein coupled receptor 70 , seven transmembrane helix receptor , candidate taste receptor T1R1

GENE ID SPECIES
654781 Danio rerio
469785 Pan troglodytes
100026826 Monodelphis domestica
100451290 Pongo abelii
80835 Homo sapiens
110326 Mus musculus
29407 Rattus norvegicus
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