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Taste Receptor, Type 1, Member 3 Proteins (TAS1R3)

The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 [PubMed 11326277]).[supplied by OMIM, Jan 2010].. Additionally we are shipping Taste Receptor, Type 1, Member 3 Antibodies (99) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TAS1R3 83756 Q7RTX0
TAS1R3 83771 Q925D8
Rat TAS1R3 TAS1R3 170634 Q923K1
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Top Taste Receptor, Type 1, Member 3 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details

TAS1R3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,

More Proteins for Taste Receptor, Type 1, Member 3 (TAS1R3) Interaction Partners

Medaka Taste Receptor, Type 1, Member 3 (TAS1R3) interaction partners

  1. Medaka T1R1 (show TAS1R1 Proteins) and T1R3 show the highest degrees of identity to mammalian T1R1 (show TAS1R1 Proteins) and T1R3, respectively.

Pig (Porcine) Taste Receptor, Type 1, Member 3 (TAS1R3) interaction partners

  1. discovery of a gene regulatory network related to the porcine umami taste receptor TAS1R1 (show TAS1R1 Proteins)/TAS1R3

  2. The gene was shown to reside on swine chromosome 6q22-->q23, from which three types of mRNAs were generated. High expressions of TAS1R3 were revealed in tongue, kidney, and testis

Human Taste Receptor, Type 1, Member 3 (TAS1R3) interaction partners

  1. TAS1R3 gene rs307355 polymorphism found independent risk factor for dental caries experience by logistic regression & increased risk of caries. Moderate caries (4-7 caries) found to be associated w/TAS1R3 rs307355 heterozygous genotype

  2. T1R3 gene expression in the tongue is suppressed by chemotherapy.

  3. The transcripts of TAS1R3 and UCN2 (show UTS2 Proteins) in peripheral blood cells may be considered potential biomarkers of consumption of sugary and fatty food, respectively, to complement data of food-intake questionnaires.

  4. human and mouse membrane trafficking systems for sweet taste receptors T1r2 (show TAS1R2 Proteins) and T1r3

  5. A complex molecular mechanism involving changes in the properties of both the orthosteric and non-orthosteric sites of T1R1 (show TAS1R1 Proteins) underlies the determination of ligand specificity in mammalian T1R1 (show TAS1R1 Proteins)/T1R3.

  6. effects of artificial sweeteners on adipose tissue may be largely independent of the classical sweet taste receptors, T1R2 (show TAS1R2 Proteins) and T1R3

  7. Five amino acid residues in cysteine-rich domain of human T1R3 were involved in the response for sweet-tasting protein, thaumatin

  8. T1R3 is a receptor responsible for the detection of calcium by taste.

  9. Overexpressed the human N-terminal domain of T1R3 in E. coli and found that the refolded protein behaves as a dimer; showed that hT1R3-NTD is functional and capable of binding sucralose with an affinity in the millimolar range.

  10. Data show that that Tas1r1 (show TAS1R1 Proteins) and Tas1r3 are expressed in murine and human spermatozoa.

Mouse (Murine) Taste Receptor, Type 1, Member 3 (TAS1R3) interaction partners

  1. T1R3 and alpha-gustducin (show GNAT3 Proteins) exhibited a stage-dependent expression pattern during mouse development, and a cell-specific pattern during the spermatogenic cycle.

  2. Low concentration of endogenous GC is necessary and sufficient for induction of T1R3 expression. Higher concentrations may inhibit such induction. This inhibitory effect may be due, at least in part, to a direct action of GC on taste cells.

  3. T1R1/T1R3 have roles in regulating ERK1/2 and mTORC1 in MIN6 cells

  4. Mice possess two taste transduction pathways for sugars. One mediates behavioral attraction to sugars and requires an intact T1r2 (show TAS1R2 Proteins)+T1r3. The other mediates cephalic phase insulin (show INS Proteins) release but does not require an intact T1r2 (show TAS1R2 Proteins)+T1r3.

  5. Taken together, our study raises the possibility that MyoD (show MYOD1 Proteins) and Myogenin (show MYOG Proteins) might control skeletal muscle metabolism and homeostasis through the regulation of T1R3 promoter activity.

  6. Mice lacking the Tas1r3 taste receptor gene display impaired glucose metabolism.

  7. Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 (show GRM4 Proteins) knockout mice

  8. T1R3 is expressed mainly in beta-cells and the expression levels are different depending upon the nutritional and metabolic conditions.

  9. In the Tas1r3-/- strain, in addition to disappearance of taste preference for sucrose, glucose tolerance is also substantially reduced, and insulin (show INS Proteins) resistance is observed.

  10. human and mouse membrane trafficking systems for sweet taste receptors T1r2 (show TAS1R2 Proteins) and T1r3

Taste Receptor, Type 1, Member 3 (TAS1R3) Protein Profile

Protein Summary

The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001

Gene names and symbols associated with TAS1R3

  • taste receptor, type 1, member 3 (TAS1R3)
  • taste receptor, type 1, member 3 (tas1r3)
  • taste receptor, type 1, member 3 (Tas1r3)
  • Sac protein
  • T1r3 protein
  • tas1r3 protein

Protein level used designations for TAS1R3

taste receptor type 1 member 3 , zfT1R3 , taste receptor, type 1, member 3 , sweet taste receptor T1R3 , saccharin preference protein , taste receptor T1R3

GENE ID SPECIES
511517 Bos taurus
562318 Danio rerio
428182 Gallus gallus
705738 Macaca mulatta
778008 Takifugu rubripes
100049303 Oryzias latipes
100127440 Sus scrofa
83756 Homo sapiens
83771 Mus musculus
170634 Rattus norvegicus
100136905 Felis catus
489594 Canis lupus familiaris
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