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TAS2R38 encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Additionally we are shipping Taste Receptor, Type 2, Member 38 Kits (7) and Taste Receptor, Type 2, Member 38 Proteins (4) and many more products for this protein.
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Human Polyclonal TAS2R38 Primary Antibody for IHC, WB - ABIN350973
Bufe, Hofmann, Krautwurst, Raguse, Meyerhof: The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. in Nature genetics 2002
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Human Polyclonal TAS2R38 Primary Antibody for IF (p), IHC (p) - ABIN1385568
Maurer, Wabnitz, Kahle, Stegmaier, Prior, Giese, Gaida, Samstag, Hänsch: Tasting Pseudomonas aeruginosa Biofilms: Human Neutrophils Express the Bitter Receptor T2R38 as Sensor for the Quorum Sensing Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone. in Frontiers in immunology 2015
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Study did not find an association between TAS2R38 genotype and chronic rhinosinusitis (CRS (show CARS Antibodies)), thus questioning its real contribution to CRS (show CARS Antibodies) susceptibility.
The expression of TAS2R38 in placental tissues points to further new functions and hitherto unknown endogenous ligands of TAS2Rs far beyond bitter tasting.
Our investigation indicates that T2R38 genotype correlates both with SNOT-22 scores and rhinologic-specific quality of life in DeltaF508 homozygous cystic fibrosis (show S100A8 Antibodies) patients
Variability in perceived bitterness of capsaicin and ethanol were significantly associated with TAS2R38
This study suggest that: 1) alexithymia, in addition to the TAS2R38 polymorphism, may play a role in responsiveness to the aversive and bitter taste of PROP; and 2) alexithymia.
phagocytes are activated via a rather specialized receptor that was not previously described on myeloid cells, the bitter taste receptor T2R38.
TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis.
This study finding significant excess of rare nonsynonymous variants exclusive to European Americans smokers in TAS2R38.
T2R38 is expressed in distinct populations of enteroendocrine cells in the human colonic mucosa. It colocalized with CCK-, GLP1- or PYY-IR. There were more T2R38-positive cells in overweight/obese subjects.
The novel TAS2R38 AVV haplotype was associated with alcohol intake in Mexican-Mestizo population.
This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).
taste receptor, type 2, member 38
, taste receptor, type 2, member 7-like
, taste receptor type 2 member 38
, taste receptor type 2 member 26
, PTC bitter taste receptor
, taste receptor type 2 member 61
, bitter taste receptor TAS2R38