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TECPR1 encodes a tethering factor involved in autophagy. Additionally we are shipping TECPR1 Antibodies (25) and and many more products for this protein.
The concerted interactions among TECPR1, Atg12-Atg5, and PtdIns(3)P provide the fusion specificity between autophagosomes and lysosomes and that the assembly of this complex initiates the autophagosome maturation process.
Although Tecpr1-deficient mice appear normal, Tecpr1-deficient mouse embryo fibroblasts were defective for selective autophagy and supported increased intracellular multiplication of Shigella.
This gene encodes a tethering factor involved in autophagy. The encoded protein is found at autolysosomes, and is involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy
tectonin beta-propeller repeat-containing protein 1
, tectonin beta-propeller repeat containing 1
, tectonin beta-propeller repeat-containing protein 1-like