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TNC encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. Additionally we are shipping Tenascin C Kits (54) and Tenascin C Proteins (17) and many more products for this protein.
Showing 10 out of 290 products:
Human Monoclonal TNC Primary Antibody for CyTOF, ELISA - ABIN259023
Tsunoda, Inada, Kalembeyi, Imanaka-Yoshida, Sakakibara, Okada, Katsuta, Sakakura, Majima, Yoshida: Involvement of large tenascin-C splice variants in breast cancer progression. in The American journal of pathology 2003
Show all 17 references for ABIN259023
Guinea Pig Monoclonal TNC Primary Antibody for EIA, IHC (fro) - ABIN1109217
Dvorak, Morgan, Lichtenstein, Weller, Schleimer: RNA is closely associated with human mast cell secretory granules, suggesting a role(s) for granules in synthetic processes. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000
Show all 16 references for ABIN1109217
Rat (Rattus) Monoclonal TNC Primary Antibody for ICC, IHC - ABIN1742432
Siddiqui, Horvat-Bröcker, Faissner: The glia-derived extracellular matrix glycoprotein tenascin-C promotes embryonic and postnatal retina axon outgrowth via the alternatively spliced fibronectin type III domain TNfnD. in Neuron glia biology 2010
Show all 5 references for ABIN1742432
Human Monoclonal TNC Primary Antibody for IHC (p), IP - ABIN94480
Tökés, Hortoványi, Csordás, Kulka, Mózes, Hatalyák, Kádár: Immunohistochemical localisation of tenascin in invasive ductal carcinoma of the breast. in Anticancer research 1999
Show all 4 references for ABIN94480
Human Monoclonal TNC Primary Antibody for EIA, IHC (p) - ABIN112483
Faustino, van Garderen, Schalken, Nederbragt: Tenascin expression in normal, hyperplastic, dysplastic and neoplastic canine mammary tissues. in Journal of comparative pathology 2002
Show all 4 references for ABIN112483
Human Monoclonal TNC Primary Antibody for IHC (fro), IF - ABIN1109218
Saga, Yagi, Ikawa, Sakakura, Aizawa: Mice develop normally without tenascin. in Genes & development 1992
Show all 3 references for ABIN1109218
Human Polyclonal TNC Primary Antibody for ELISA, WB - ABIN561398
He, Liu, Zhu, Xie, Costello, Talsma, Flack, Crowley, Dimeco, Vescovi, Fan, Lubman: Glycoproteomic analysis of glioblastoma stem cell differentiation. in Journal of proteome research 2011
Human Polyclonal TNC Primary Antibody for IP, IHC - ABIN1585367
Fujimoto, Suzuki, Shiba, Shimojo, Imanaka-Yoshida, Yoshida, Kanamaru, Matsushima, Taki: Tenascin-C induces prolonged constriction of cerebral arteries in rats. in Neurobiology of disease 2013
Results suggest that sequence variants in TNC and COL5A1 (show COL5A1 Antibodies) genes are associated with superficial digital flexor tendinopathy in TB racehorses. In
High TNC expression is associated with retinoblastoma.
prepartum and postpartum TN-C serum levels significantly higher in mild and severe preeclampsia than in healthy pregnancy
Tenascin-C overexpression in cancer cells and stromal fibroblasts was an independent poor prognostic factor for overall survival and disease-free survival esophageal squamous cell carcinoma patients.
Serum TNC levels are significantly raised and correlate with various clinical and laboratory variables of disease activity in children with enthesitis-related arthritis
This study has identified tenascin-C as a promoter of the invasiveness of brain tumor-initiating cells through a mechanism involving ADAM-9 (show ADAM9 Antibodies) proteolysis via the c-Jun NH2-terminal kinase (show MAPK8 Antibodies) pathway.
Co-expression of Matrix metalloproteinase-9 (show MMP9 Antibodies) and Tenascin-C was associated with poorer prognosis and was found to be an independent predictor of survival
Studied the expression of TNC in tissue microarrays including 17 GBMs, 18 WHO grade III astrocytomas, 15 WHO grade II astrocytomas, 4 WHO grade I astrocytomas, and 7 normal brain tissue samples by immunohistochemical staining.
No difference in tenascin-C expression was found in COPD (show ARCN1 Antibodies).
miR (show MLXIP Antibodies)-133a enhances the protective capacity of cardiac progenitors cells after myocardial infarction
A pivotal role for TNC in tuning the local immune response to establish equilibrium between disseminated nodal cancer stem cells and the immune system.
Tenascin-C may be an important mediator in the development of brain edema and blood-brain barrier disruption following subarachnoid hemorrhage, mechanisms for which may involve MAPK (show MAPK1 Antibodies)-mediated MMP-9 (show MMP9 Antibodies) induction and ZO-1 (show TJP1 Antibodies) degradation
TN-C aggravates autoimmune myocarditis by driving the dendritic cell activation and Th17 differentiation via toll-like receptor 4 (show TLR4 Antibodies).
TNC supports the stress-induced expression of extracellular matrix that reinforce the aorta and the stress-induced excessive inflammatory response in the aorta.
TNC plays an important role in TMJ wound healing, especially for wounds generated by mechanical stress.
Tenascin-C is required for normal Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling in the whisker follicle stem cell niche.
TNC downregulates Dickkopf-1 (DKK1 (show DKK1 Antibodies)) promoter activity through the blocking of actin stress fiber formation, activates Wnt (show WNT2 Antibodies) signaling, and induces Wnt (show WNT2 Antibodies) target genes in tumor and endothelial cells.
The increased levels of elastin (show ELN Antibodies), type V collagen (show COL5A1 Antibodies) and tenascin C are probably the result of increased expression by fibroblastic cells; reversely, elastin (show ELN Antibodies) influences myofibroblast differentiation
Elevated tenascin-C expression in globoid cell leukodystrophy modified microglial functional response to psychosine.
Tenascin-C-derived peptide TNIIIA2 highly enhances cell survival and platelet-derived growth factor (PDGF (show PDGFA Antibodies))-dependent cell proliferation through potentiated and sustained activation of integrin alpha5beta1.
FHL2 (show FHL2 Antibodies)-deficient mice developed a severe and long-lasting lung pathology due to enhanced expression of tenascin C and impaired activation of inflammation-resolving macrophages.
TNC does not appear to contribute directly to outflow resistance in the eye.
TNC could be a potential candidate gene for meat quality traits in pigs.
tenascin binds to fibronectin (show FN1 Antibodies) at a cryptic binding site
Reloading of atrophied rat soleus muscle induces tenascin-C expression around damaged muscle fibers. Increase of rat soleus muscle loading modifies basement membrane of damaged muscle fibers through ectopic endomysial expression of tenascin-C.
tenascin-C is part of a specialized extracellular matrix in the region of the horizontal myoseptum that influences the growth of motor axons
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration.
, tenascin C (hexabrachion)
, GP 150-225
, glioma-associated-extracellular matrix antigen
, hexabrachion (tenascin)
, myotendinous antigen
, tenascin-C isoform 14/AD1/16