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Isoform 2 inhibits neurite outgrowth and cell migration in hippocampal explants while isoform 1 does not have this affect.. Additionally we are shipping Tenascin N Kits (5) and and many more products for this protein.
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This study demonstrated that the genetic defect was totally or partly clarified in 21 patients with nine of them having potential disease-causing mutations in TTN (show TTN Antibodies).
Results show that tenascin-W acts as a niche component for breast cancer metastasis to bone by supporting cell (show PTPRJ Antibodies) migration and cell proliferation of the cancer cells.
The expression of tenascin-W is dependent on p38MAPK (show MAPK14 Antibodies) and JNK (show MAPK8 Antibodies) signaling pathways in mammary tumors. (tenascin-W)
data imply that tenascin-W expression in the activated tumor stroma facilitates tumorigenesis by supporting the migratory behavior of breast cancer cells
results reveal a clear association between elevated levels of tenascin-W and the presence of colorectal cancer and breast cancer
TN-C (show TNC Antibodies) may enhance inflammatory responses by accelerating macrophage migration and synthesis of proinflammatory/profibrotic cytokines via integrin alphaVbeta3 (show ITGAV Antibodies)/FAK (show PTK2 Antibodies)-Src (show SRC Antibodies)/NF-kappaB (show NFKB1 Antibodies), resulting in increased fibrosis.
the CD34 (show CD34 Antibodies)-positive whisker follicle stem cell niche contains both tenascin-C (show TNC Antibodies) and tenascin-W, and these glycoproteins might play a role in directing the migration and proliferation of these stem cells
Tenascin-W is able to inhibit cell spreading in vitro and it is upregulated in dermal fibroblasts taken from a tenascin-C (show TNC Antibodies) knockout mouse.
Tenascin-W is expressed during palate formation, osteogenesis and smooth muscle development.
Our results indicate that TN-W is a novel marker of preosteoblasts in early stage of osteogenesis, and that TN-W inhibits cell proliferation and differentiation of preosteoblasts mediated by canonical Wnt (show WNT2 Antibodies) signaling.
Isoform 2 inhibits neurite outgrowth and cell migration in hippocampal explants while isoform 1 does not have this affect.
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