anti-Tenascin XB (TNXB) Antibodies

TNXB encodes a member of the tenascin family of extracellular matrix glycoproteins. Additionally we are shipping TNXB Kits (26) and TNXB Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNXB 415089  
TNXB 7148 P22105
TNXB 81877  
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Top anti-TNXB Antibodies at

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TNXB Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
Mouse Rat Un-conjugated ICC, IHC (fro), IF, IP, IHC, ELISA, WB   0.05 mL Log in to see 7 to 9 Days
Human Mouse Un-conjugated WB Western Blot analysis of TNXB expression in transfected 293T cell line by TNXB MaxPab polyclonal antibody.Lane 1: TNXB transfected lysate(74.03 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
Human Rabbit Un-conjugated IHC (p) 1 mL Log in to see 2 to 3 Days
Human Mouse Un-conjugated IHC (p), IP, IHC, WB Immunohistochemistry: Tenascin X Antibody (T2H5) [ABIN269145] - Fig. 1. Immunohistochemistry staining of tonsil (paraffin-embedded sections) with anti-human Tenascin X Antibody (T2H5). 0.1 mg Log in to see 7 to 9 Days
Human Mouse Un-conjugated IP, ELISA, WB 100 μg Log in to see 7 to 9 Days
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TNXB is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 16 Days

TNXB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,

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Mouse (Murine) ,

Top referenced anti-TNXB Antibodies

  1. Mouse (Murine) Monoclonal TNXB Primary Antibody for ICC, IHC (fro) - ABIN267551 : Aufderheide, Ekblom: Tenascin during gut development: appearance in the mesenchyme, shift in molecular forms, and dependence on epithelial-mesenchymal interactions. in The Journal of cell biology 1989 (PubMed)
    Show all 7 references for 267551

  2. Human Polyclonal TNXB Primary Antibody for IHC, ELISA - ABIN1535407 : Tee, Thomson, Bristow, Miller: Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X. in Genomics 1996 (PubMed)

  3. Human Polyclonal TNXB Primary Antibody for WB - ABIN521039 : Hu, Zhang, Zhang, Li, Zhu, Shao, Zeng, Xu: Comparative serum proteome analysis of human lymph node negative/positive invasive ductal carcinoma of the breast and benign breast disease controls via label-free semiquantitative shotgun technology. in Omics : a journal of integrative biology 2009 (PubMed)

More Antibodies against TNXB Interaction Partners

Human Tenascin XB (TNXB) interaction partners

  1. patients with the TNX-deficient type EDS typically have generalized joint hypermobility, skin hyperextensibility and easy bruising. In contrast to the classical type, the inheritance pattern is autosomal recessive and atrophic scarring is absent. Molecular analysis of TNXB in a diagnostic setting is challenging.

  2. the identification of a rare missense variant in TNXB in combination with a positive family history of VUR and joint hypermobility may represent a non-invasive method to diagnose PVUR and warrants further evaluation in other cohorts

  3. We then quantified the tenascin-X level in serum of patients and identified tenascin-X as potent marker for ovarian cancer, showing that secretomic analysis is suitable for the identification of protein biomarkers when combined with protein immunoassay.

  4. these results suggest that mutations in TNXB can cause hereditary primary vesicoureteral reflux .

  5. Noticeable decreased expression of tenascin-X in calcific aortic valves.

  6. Tenascin-X haploinsufficiency was associated with Ehlers-Danlos syndrome in patients with congenital adrenal hyperplasia

  7. Genome-wide association study of age-related macular degeneration identifies TNXB, FKBPL (show FKBPL Antibodies) and NOTCH4 (show NOTCH4 Antibodies) as candidate susceptibility genes.

  8. Combined analysis of tenascin-C (show TNC Antibodies) expression and the nodule size improved the prediction of malignancy in this patient cohort.

  9. rs204887 itself or a nearby variant is unlikely to play a major role in the development of schizophrenia although a cumulative contribution of rare variants in the TNXB gene cannot be ruled out.

  10. Three point mutations in TNX gene were found to be associated with hypermobility type Ehlers-Danlos syndrome (EDS) . The phenotypic effects of V1195M mutation on 7th fibronectin (show FN1 Antibodies) Type III domain (TNXfn7) with regards to EDS were investigated.

Mouse (Murine) Tenascin XB (TNXB) interaction partners

  1. Tenascin-x is an initiator of myocardial fibrosis and ACM development via upregulation of TGFbeta (show TGFB1 Antibodies)(1) and downregulation of PPARgamma (show PPARG Antibodies).

  2. Altered properties of the force transmission pathways of muscle due to TNX deficiency directly affect muscle function in TNX KO mice. Such effects are likely to contribute to muscle weakness experienced by patients with Ehlers-Danlos syndrome.

  3. Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition

  4. TNX has either a redundant or a very subtle function in the macromolecular organization in the peripheral nerve

  5. Tnx plays a role in the regulation of cell-cell and cell-matrix interactions: Tnx-null fibroblasts exhibit weaker adhesive properties to fibronectin (show FN1 Antibodies) and B16 melanoma cells than do wild-type fibroblasts.

  6. Induction of MMP-2 (show MMP2 Antibodies) by Tnx deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase (show YES1 Antibodies) phosphorylation pathway.

  7. TNX is unlikely to be involved in matrix deposition in the early phase of wound healing, but it is required in the later phase when remodeling and maturation of the matrix establishes and improves its biomechanical properties.

  8. TNX knockout mice have mild pregnancy-related abnormalities.

  9. localizations of Tn-X in the leptomeningeal trabecula (TB) of adult mice and in the connective tissue of the choroid plexus (CP) in the brains of mice

Cow (Bovine) Tenascin XB (TNXB) interaction partners

  1. Tenascin-X promotes activation of latent TGF-beta1 (show TGFB1 Antibodies) and subsequent epithelial to mesenchymal transition in mammary epithelial cells.

  2. mechanical analysis of collagen gels showed an increased compressive resistance of the gels containing tenascin-X, indicating that this protein might be directly involved in determining the mechanical properties of collagen-rich tissues in vivo.

  3. tenascin-X, via trimerization and multiple interactions with components of collagenous fibrils, plays a crucial role in the organisation of extracellular matrices.

  4. Tenascin-X is an elastic protein and the fibronectin (show FN1 Antibodies) type III (FnIII) domains can unfold under a stretching force and refold to regain their mechanical stability upon the removal of the stretching force.

TNXB Antigen Profile

Protein Summary

This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Tenascin XB (TNXB) Antibodies

  • tenascin XB (Tnxb) antibody
  • tenascin XB (TNXB) antibody
  • tenascin-X (TN-X) antibody
  • EDS3 antibody
  • HXBL antibody
  • TENX antibody
  • Tn-mhc antibody
  • TN-X antibody
  • TN-Y antibody
  • TNX antibody
  • TNXB antibody
  • TNXB1 antibody
  • TNXB2 antibody
  • TNXBS antibody
  • XB antibody
  • XBS antibody

Protein level used designations for anti-Tenascin XB (TNXB) Antibodies

tenascin X pseudogene , tenascin XB , tenascin Y , tenascin X B , tenascin-X-like , growth-inhibiting protein 45 , hexabrachion-like protein , tenascin XB1 , tenascin XB2 , tenascin-X , tenascin X

415089 Rattus norvegicus
396106 Gallus gallus
462578 Pan troglodytes
750749 Pan troglodytes
100434533 Pongo abelii
100597679 Nomascus leucogenys
7148 Homo sapiens
81877 Mus musculus
100682877 Canis lupus familiaris
282654 Bos taurus
445520 Sus scrofa
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