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Tenomodulin Proteins (TNMD)

TNMD encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. Additionally we are shipping Tenomodulin Antibodies (44) and Tenomodulin Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNMD 64102 Q9H2S6
TNMD 64103 Q9EP64
TNMD 64104 Q9ESC2
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Top Tenomodulin Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,693.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TNMD Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Tenomodulin (TNMD) Interaction Partners

Human Tenomodulin (TNMD) interaction partners

  1. TNMD is upregulated in adipose tissue of insulin-resistant versus insulin-sensitive individuals. TNMD expression increases in human preadipocytes during differentiation, whereas silencing TNMD blocks adipogenesis.

  2. results suggest that Tnmd acts on the maturation or maintenance of the PDL by positively regulating cell adhesion via its BRICHOS domain

  3. Report differential expression and cellular localization of novel isoforms of the tendon biomarker tenomodulin and suggest possible roles in tenocyte proliferation and tendon injury.

  4. According to these results the sequence variation of TNMD is not associated with alzheimer disease, but might modify the effect of APOE (show APOE Proteins) epsilon4-allele in women.

  5. Tenomodulin is expressed abundantly in the elastin (show ELN Proteins)-rich subendothelial outer layer of the normal chordae tendineae cordis.

  6. TNMD could be a novel candidate gene for age-related macular degeneration.

  7. Human adipose tissue TNMD gene expression is highly affected by obesity, adipose tissue location, and weight loss, indicating that TNMD may play a role in adipose tissue function.

Pig (Porcine) Tenomodulin (TNMD) interaction partners

  1. Tenomodulin is expressed abundantly in the elastin (show ELN Proteins)-rich subendothelial outer layer of the normal chordae tendineae cordis.

Mouse (Murine) Tenomodulin (TNMD) interaction partners

  1. Upon high-fat diet feeding, transgenic mice overexpressing Tnmd develop increased epididymal white adipose tissue (eWAT) mass, and preadipocytes derived from Tnmd transgenic mice display greater proliferation, consistent with elevated adipogenesis.

  2. Loss of Tnmd affects significantly the self-renewal and senescence properties, but not the multipotential of tendon stem cells.

  3. In our study of MM development, the laminar structure regulating TeM also prevents vascular invasion during the formation of compartment of the MM.

  4. Results suggest that tenomodulin (Tnmd) is a regulator of tenocyte proliferation and is involved in collagen fibril maturation but do not confirm an in vivo involvement of Tnmd in angiogenesis.

  5. The expression domains of ChM-I (show LECT1 Proteins) and TeM during vertebrate development incorporate the typical avascular regions of the mesenchymal tissues.

  6. Tenomodulin is expressed abundantly in the elastin (show ELN Proteins)-rich subendothelial outer layer of the normal chordae tendineae cordis.

Tenomodulin (TNMD) Protein Profile

Protein Summary

This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated.

Gene names and symbols associated with Tenomodulin Proteins (TNMD)

  • tenomodulin (TNMD)
  • tenomodulin (LOC100229770)
  • tenomodulin (tnmd)
  • tenomodulin (Tnmd)
  • 1110017I01Rik protein
  • Bricd4 protein
  • ChM1L protein
  • TEM protein
  • zgc:172161 protein

Protein level used designations for Tenomodulin Proteins (TNMD)

tenomodulin , BRICHOS domain containing 4 , chondromodulin-1-like protein , chondromodulin-I-like protein , chondromodulin-IB , hChM1L , hTeM , myodulin , tendin , mChM1L , mTeM , rChM1L , rTeM , teM

GENE ID SPECIES
100033840 Equus caballus
473697 Pan troglodytes
700526 Macaca mulatta
100229770 Taeniopygia guttata
100589123 Nomascus leucogenys
556984 Danio rerio
404530 Gallus gallus
64102 Homo sapiens
480980 Canis lupus familiaris
100048961 Sus scrofa
781292 Bos taurus
64103 Mus musculus
64104 Rattus norvegicus
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