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The protein encoded by TSPY1 is found only in testicular tissue and may be involved in spermatogenesis. Additionally we are shipping Testis Specific Protein, Y-Linked 1 Antibodies (49) and many more products for this protein.
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TSPY and TSPX (show TSPYL2 Proteins) exert opposing effects on the transactivation functions of AR and AR-Vs important for various physiological and disease processes sensitive to male sex hormone actions, thereby not only affecting the pathogenesis of male-specific prostate cancer but also likely contributing to sex differences in the health and diseases of man.
The aim of this study was to compare two Y chromosome markers-SRY (show SRY Proteins) and DYS14-for their utility in the diagnosis of fetal gender.
Studies indicate that TSPY1 (testis-specific protein, Y-linked 1) gene has been identified to be the most important candidate gene for gonadoblastoma.
The oncogenic events leading to an ectopic activation of TSPY and/or inactivating mutation/epigenetic silencing of TSPX (show TSPYL2 Proteins) could collectively contribute to the sexual dimorphism(s) in HCC (show FAM126A Proteins) and related liver cancers in male-biased manners.
A combined genetic analysis of the TSPY1 copy number and the gr/gr (show GSR Proteins) deletion could inform the clinical counselling of infertile couples.
evaluate TSPY (testis specific protein on the Y chromosome) gene and 5'UTR (UnTranslated Region) polymorphisms in men with impaired fertility compared to fertile controls
The expression analysis of genes OCT4 (show POU5F1 Proteins), SRY (show SRY Proteins), and TSPY in the dysgenetic gonads of Turner syndrome patients may allow introducing modifications in the microenvironment that could contributed to a malignant transformation process.
A daughter who carried the der (show GDF3 Proteins) Y had the clinical features of Prader-Willi syndrome while a son who carries the der (show GDF3 Proteins) 15 has mild developmental delay and hypogonadism.
Nested PCR revealed the testis specific protein 1 (show SPZ1 Proteins)-Y-linked (TSPY) gene in two women with Mayer-Rokitansky-Kuster-Hauser syndrome
the TSPYL (show TSPYL1 Proteins) gene in SIDDT affected individuals contained a homozygous frameshift mutation resulting in truncation of translation at codon 169. Truncation leads to loss of a peptide domain with strong homology to the nucleosome assembly protein family.
TSPY copy number was analyzed using relative real-time polymerase chain reaction (PCR) of the DNA of 14 different cattle breeds.
The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Approximately 35 copies of this gene are present in humans, but only a single, nonfunctional orthologous gene is found in mouse. Two transcript variants encoding different isoforms have been found for this gene.
testis specific protein, Y-linked 1
, cancer/testis antigen 78
, testis-specific Y-encoded protein 1
, Testis specific protein on Y
, testis-specific protein TSPY
, testis-specific protein, Y-encoded