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Testis-Specific Kinase 1 (TESK1) ELISA Kits

TESK1 product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Additionally we are shipping TESK1 Antibodies (33) and TESK1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse TESK1 TESK1 21754 O70146
Anti-Human TESK1 TESK1 7016 Q15569
Anti-Rat TESK1 TESK1 29460 Q63572
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More ELISA Kits for TESK1 Interaction Partners

Mouse (Murine) Testis-Specific Kinase 1 (TESK1) interaction partners

  1. In mouse testis, PPP1CC2 can form a complex with TSSK1 (show TSSK1B ELISA Kits) mediated by the direct interaction of each with the kinase substrate protein TSKS (show TSKS ELISA Kits). Interaction between PPP1CC2 and TSKS (show TSKS ELISA Kits) is mediated through an RVxF docking motif on the TSKS (show TSKS ELISA Kits) surface.

  2. HSP90 (show HSP90 ELISA Kits) function abolished the catalytic activities of TSSK4 (show TSSK4 ELISA Kits) and -6 but did not significantly alter the specific activities of TSSK1 (show TSSK1B ELISA Kits) and -2. Inhibition of HSP90 (show HSP90 ELISA Kits) resulted in increased TSSK ubiquitination and proteasomal degradation

  3. Tssk1 and Tssk2 play an important role in the regulation of sperm function.

  4. Results reveal TSSK1- and TSSK2-dependent functions of a transformed chromatoid body in post-meiotic cytodifferentiation of spermatids.

  5. The expression patterns of Tsk1 (show TSSK1B ELISA Kits) is documented throughout spermiogenesis showing an initial association of Tsk1 (show TSSK1B ELISA Kits) with cells in meiotic metaphase.

  6. Deletion of Tssk2 kinase/substrate pair is predicted to play an indispensable role during spermiogenesis

  7. Results confirm both TSSK 2 and TSKS (show TSKS ELISA Kits) persist in sperm, define a critical role of TSKS (show TSKS ELISA Kits)' N-terminus in enzyme interaction, identify Ser (show SIGLEC1 ELISA Kits) 281 as a TSKS (show TSKS ELISA Kits) phosphorylation site and indicate an indispensable role for TSSK 1 (show TSSK1B ELISA Kits) and 2 in spermiogenesis.

Human Testis-Specific Kinase 1 (TESK1) interaction partners

  1. Actin remodelling factor TESK1 is a key player in the ciliogenesis control network in which YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) and directional vesicle trafficking are integral components.

  2. the association between actopaxin (show PARVA ELISA Kits) and TESK1, which is likely regulated by phosphorylation of actopaxin (show PARVA ELISA Kits), regulates TESK1 activity and subsequent cellular spreading on fibronectin (show FN1 ELISA Kits)

  3. enhanced TESK1 activity results in increased stress fibers (via phospho-cofilin (show CFL1 ELISA Kits)), but this can be blocked by elevating Spred1 (show SPRED1 ELISA Kits)

TESK1 Antigen Profile

Antigen Summary

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.

Gene names and symbols associated with TESK1

  • testis-specific kinase 1 (TESK1) antibody
  • testis specific protein kinase 1 (Tesk1) antibody
  • testis-specific kinase 1 (Tesk1) antibody
  • testis-specific serine kinase 1 (Tssk1) antibody
  • AI326901 antibody
  • Stk22a antibody
  • TESK1 antibody
  • TSK-1 antibody
  • Tsk1 antibody
  • Tssk antibody
  • Tssk1b antibody

Protein level used designations for TESK1

testis-specific kinase 1 , testis-specific protein kinase 1 , dual specificity testis-specific protein kinase 1 , dual specificity testis-specific protein kinase 1-like , testicular protein kinase 1 , testis specific protein kinase 1 , TSSK-1 , serine/threonine kinase 22A (spermiogenesis associated) , serine/threonine-protein kinase 22A , testis-specific serine/threonine kinase , testis-specific serine/threonine-protein kinase 1

GENE ID SPECIES
465074 Pan troglodytes
527643 Bos taurus
100407135 Callithrix jacchus
21754 Mus musculus
7016 Homo sapiens
29460 Rattus norvegicus
22114 Mus musculus
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