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Testis-Specific Kinase 1 Proteins (TESK1)

TESK1 product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Additionally we are shipping TESK1 Antibodies (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TESK1 21754 O70146
TESK1 7016 Q15569
TESK1 29460 Q63572
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Top TESK1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,815.17
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

TESK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Testis-Specific Kinase 1 (TESK1) Interaction Partners

Mouse (Murine) Testis-Specific Kinase 1 (TESK1) interaction partners

  1. In mouse testis, PPP1CC2 can form a complex with TSSK1 (show TSSK1B Proteins) mediated by the direct interaction of each with the kinase substrate protein TSKS (show TSKS Proteins). Interaction between PPP1CC2 and TSKS (show TSKS Proteins) is mediated through an RVxF docking motif on the TSKS (show TSKS Proteins) surface.

  2. HSP90 (show HSP90 Proteins) function abolished the catalytic activities of TSSK4 (show TSSK4 Proteins) and -6 but did not significantly alter the specific activities of TSSK1 (show TSSK1B Proteins) and -2. Inhibition of HSP90 (show HSP90 Proteins) resulted in increased TSSK ubiquitination and proteasomal degradation

  3. Tssk1 and Tssk2 play an important role in the regulation of sperm function.

  4. Results reveal TSSK1- and TSSK2-dependent functions of a transformed chromatoid body in post-meiotic cytodifferentiation of spermatids.

  5. The expression patterns of Tsk1 (show TSSK1B Proteins) is documented throughout spermiogenesis showing an initial association of Tsk1 (show TSSK1B Proteins) with cells in meiotic metaphase.

  6. Deletion of Tssk2 kinase/substrate pair is predicted to play an indispensable role during spermiogenesis

  7. Results confirm both TSSK 2 and TSKS (show TSKS Proteins) persist in sperm, define a critical role of TSKS (show TSKS Proteins)' N-terminus in enzyme interaction, identify Ser (show SIGLEC1 Proteins) 281 as a TSKS (show TSKS Proteins) phosphorylation site and indicate an indispensable role for TSSK 1 (show TSSK1B Proteins) and 2 in spermiogenesis.

Human Testis-Specific Kinase 1 (TESK1) interaction partners

  1. Actin remodelling factor TESK1 is a key player in the ciliogenesis control network in which YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins) and directional vesicle trafficking are integral components.

  2. the association between actopaxin (show PARVA Proteins) and TESK1, which is likely regulated by phosphorylation of actopaxin (show PARVA Proteins), regulates TESK1 activity and subsequent cellular spreading on fibronectin (show FN1 Proteins)

  3. enhanced TESK1 activity results in increased stress fibers (via phospho-cofilin (show CFL1 Proteins)), but this can be blocked by elevating Spred1 (show SPRED1 Proteins)

TESK1 Protein Profile

Protein Summary

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.

Gene names and symbols associated with TESK1

  • testis-specific kinase 1 (TESK1)
  • testis specific protein kinase 1 (Tesk1)
  • testis-specific kinase 1 (Tesk1)
  • testis-specific serine kinase 1 (Tssk1)
  • AI326901 protein
  • Stk22a protein
  • TESK1 protein
  • TSK-1 protein
  • Tsk1 protein
  • Tssk protein
  • Tssk1b protein

Protein level used designations for TESK1

testis-specific kinase 1 , testis-specific protein kinase 1 , dual specificity testis-specific protein kinase 1 , dual specificity testis-specific protein kinase 1-like , testicular protein kinase 1 , testis specific protein kinase 1 , TSSK-1 , serine/threonine kinase 22A (spermiogenesis associated) , serine/threonine-protein kinase 22A , testis-specific serine/threonine kinase , testis-specific serine/threonine-protein kinase 1

GENE ID SPECIES
465074 Pan troglodytes
527643 Bos taurus
100407135 Callithrix jacchus
21754 Mus musculus
7016 Homo sapiens
29460 Rattus norvegicus
22114 Mus musculus
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