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This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. Additionally we are shipping TSSK6 Antibodies (55) and many more products for this protein.
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Human TSSK6 Primary Antibody for AA, AP - ABIN1323987
Li, Sosnik, Brassard, Reese, Spiridonov, Bates, Johnson, Anguita, Visconti, Salicioni: Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis. in Molecular human reproduction 2010
findings, for the first time, suggested an association of c.822+126T>G/C in TSSK6 with spermatogenic impairment in humans in which allele T may be a risk factor for male infertility, while alleles C and G may decrease susceptibility to male infertility
results demonstrate that SSTK is required for proper postmeiotic chromatin remodeling and male fertility
HSP90 (show HSP90 Proteins) function abolished the catalytic activities of TSSK4 (show TSSK4 Proteins) and -6 but did not significantly alter the specific activities of TSSK1 (show TSSK1B Proteins) and -2. Inhibition of HSP90 (show HSP90 Proteins) resulted in increased TSSK ubiquitination and proteasomal degradation
HSP90 (show HSP90 Proteins) is essential for functional maturation of the kinase and identify SIP (show CACYBP Proteins) as a cochaperone that is critical to the HSP90 (show HSP90 Proteins)-mediated activation of SSTK.
This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm.
testis-specific serine kinase 6
, cancer/testis antigen 72
, serine/threonine protein kinase SSTK
, small serine/threonine kinase
, testis-specific serine/threonine-protein kinase 6
, serine/threonine-protein kinase SSTK
, testis-specific kinase 6