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anti-Tet Methylcytosine Dioxygenase 1 (TET1) Antibodies

Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC). Additionally we are shipping TET1 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TET1 80312 Q8NFU7
TET1 52463 Q3URK3
TET1 309902  
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Top anti-TET1 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IP, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ChIPSeq, ChIP, WB Tet1 (pAb) tested by Western blot. Tet1 detection by Western blot. The analysis was performed using 40 µg mouse ES nuclear extract and Tet1 at a 1:500 dilution. Tet1 antibody (pAb) tested by ChIP-Seq. ChIP was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 25 µg of chromatin from a human testicle and 4 µl of TET1 antibody. ChIP DNA was sequenced on the Illumina HiSeq and 15 million sequence tags were mapped to identify TET1 binding sites. TET1 ChIP-Seq data shows the expected enrichment of TET1 at CpG islands. 100 μL Log in to see 1 to 2 Days
$478.33
Details
Mouse Rabbit Un-conjugated IP, WB Western blot analysis of extracts of A431 cell lines, using TET1 antibody. 100 μL Log in to see 9 Days
$302.50
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TET1 is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IP   100 μL Log in to see 8 to 10 Days
$581.17
Details
Mouse Rabbit Un-conjugated ELISA, WB   400 μL Log in to see 8 to 10 Days
$463.83
Details

TET1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Rat (Rattus)


More Antibodies against TET1 Interaction Partners

Human Tet Methylcytosine Dioxygenase 1 (TET1) interaction partners

  1. Noncovalent binding of ADP-ribose polymers with TET1 catalytic domain decreases TET1 hydroxylase activity while the covalent PARylation stimulates TET1 enzyme. In addition, TET1 activates PARP-1/ARTD1 (show PARP1 Antibodies) independently of DNA breaks.

  2. Expression levels of TET1 are low in renal carcinoma (show TSC2 Antibodies), particularly in high grade tumors.

  3. our study demonstrated that DNA hypomethylation at the TET1 promoter was associated with childhood asthma in African Americans.

  4. Identify of MLL (show MLL Antibodies)-fusion/MYC (show MYC Antibodies) dash, verticalmiR-26 dash, verticalTET1 signaling circuit in MLL (show MLL Antibodies)-rearranged acute myeloid leukemia (show BCL11A Antibodies).

  5. The expression (mRNA and protein levels) of DNMT1 (show DNMT1 Antibodies) and TET1 is increased in PFC (show CFP Antibodies) of SZ and BP disorder patients.

  6. Here, the authors reveal the methylcytosine dioxygenases TET1 and TET2 (show TET2 Antibodies) as active regulators of CTCF (show CTCF Antibodies)-mediated alternative splicing through conversion of 5-methylcytosine to its oxidation derivatives.

  7. these data suggest a dual function of GADD45a (show GADD45A Antibodies) in oxidative DNA demethylation, to promote directly or indirectly TET1 activity and to enhance subsequent 5-formylcytosine/5-carboxylcytosine removal.

  8. The downregulation of ALDOB (show ALDOB Antibodies) could indicate a poor prognosis for HCC (show FAM126A Antibodies) patients. In addition, ALDOB (show ALDOB Antibodies) inhibits the invasive features of cell lines partly through TET1 expression.

  9. Our study indicates that early breast cancer patients with decreased expression of TET1 mRNA had worse overall survival.

  10. Aberrant TET1 Methylation is closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer

Mouse (Murine) Tet Methylcytosine Dioxygenase 1 (TET1) interaction partners

  1. Reprogramming of spermatogonial stem cells from Tet1 and Tet2 (show TET2 Antibodies) double knockout mice however lacked demethylation of H19 (show NCKAP1 Antibodies) imprinting control regions.

  2. The critical roles of TET1/2 individually.

  3. These results uncover the hypermethylation of DNA methylation (show HELLS Antibodies) canyons as the genomic key feature of Tet1/Tet2 (show TET2 Antibodies) double-knockout mouse embryonic fibroblasts.

  4. Lin28A (show LIN28A Antibodies) binds active promoters and recruits Tet1 to regulate gene expression via epigenetic DNA modifications.

  5. Knockdown of Tet1 and Tet3 (show TET3 Antibodies) by RNAi in ex vivo cerebellar slice cultures inhibits dendritic arborization of developing cerebellar granule cells, a critical step in circuit formation

  6. findings demonstrate that DAZL (show DAZL Antibodies) associates with mRNA of Tet1, a catalyst of 5-hydroxylation of methyl-cytosine, and enhances Tet1 mRNA translation; DAZL (show DAZL Antibodies) enhances TET1-mediated cytosine hydroxymethylation in embryonic stem cells that are actively reprogramming to a pluripotent ground state

  7. The miR (show MLXIP Antibodies)-29b/Tet1 regulatory axis promotes the mesendoderm lineage formation by inducing the Nodal signaling pathway and repressing the key target of the active demethylation pathway, thymine DNA glycosylase (show TDG Antibodies).

  8. Both TET1 and TET2 (show TET2 Antibodies) are required for the repression of embryonic stem cells differentiation by PRDM14 (show PRDM14 Antibodies).

  9. This study expands the knowledge about Tet1 involvement in stemness circuits in embryonic stem cells and provides evidence for a transcriptional relationship between Tet1 and Polycomb (show CBX2 Antibodies) repressive complex 2 in adult proliferating cells.

  10. Embryos lacking Tet1 and Tet3 (show TET3 Antibodies) (Tet1/3 DKO) displayed a strong loss of 5-hydroxymethylcytosine (5hmC) and a concurrent increase in 5-methylcytosine (5mC) at the eight-cell stage.

Cow (Bovine) Tet Methylcytosine Dioxygenase 1 (TET1) interaction partners

  1. TET3 (show TET3 Antibodies) dioxygenase was present in the very first embryo stages, in contrast to TET1 and AICDA (show AICDA Antibodies).

TET1 Antigen Profile

Protein Summary

Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC). Might initiate a process leading to cytosine demethylation through deamination into 5- hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. Preferentially binds to CpG-rich sequences at promoters of both transcriptionally active and polycomb-repressed genes. By controlling the levels of 5mC and 5hmC at gene promoters, it may regulate the gene expression silencing induced by cytosine methylation. May have a dual function by also repressing the expression of a subset of genes through recruitment of transcriptional repressors to promoters. Involved in the balance between pluripotency and lineage commitment of cells it plays a role in embryonic stem cells maintenance and inner cell mass cell specification.

Gene names and symbols associated with TET1

  • tet methylcytosine dioxygenase 1 (TET1) antibody
  • tet methylcytosine dioxygenase 1 (Tet1) antibody
  • tet oncogene 1 (TET1) antibody
  • 2510010B09Rik antibody
  • AA517754 antibody
  • bA119F7.1 antibody
  • BB001228 antibody
  • Cxxc6 antibody
  • D10Ertd17e antibody
  • LCX antibody
  • mKIAA1676 antibody

Protein level used designations for TET1

CXXC finger 6 , CXXC zinc finger 6 , CXXC-type zinc finger protein 6 , leukemia-associated protein with a CXXC domain , methylcytosine dioxygenase TET1 , ten-eleven translocation 1 gene protein , ten-eleven translocation-1 , tet oncogene 1 , ten-eleven translocation 1 gene protein homolog , tet methylcytosine dioxygenase 1

GENE ID SPECIES
80312 Homo sapiens
52463 Mus musculus
479229 Canis lupus familiaris
100153073 Sus scrofa
513640 Bos taurus
309902 Rattus norvegicus
423690 Gallus gallus
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