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anti-Tet Methylcytosine Dioxygenase 2 (TET2) Antibodies

The protein encoded by TET2 is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. Additionally we are shipping TET2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TET2 54790 Q6N021
TET2 214133 Q4JK59
TET2 310859  
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Top anti-TET2 Antibodies at antibodies-online.com

Showing 10 out of 121 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Goat Un-conjugated EIA, IHC (p) Immunohistochemistry: TET2 Antibody staining of Paraffin Embedded Human Spleen at 4 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TET2 in SK-N-SH cell lysate with TET2 antibody at 1 µg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p)   0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Human Goat Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated WB TET2 Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TET2 antibody detected the TET2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IP, WB Tes2 mAb (Clone 21F11) tested by Immunoprecipitation. Tet2 detection by Immunoprecipitation. Lane 1: Input (25 µg of HL-60 whole cell lysate). Lane 2: Negative control mAb. Lane 3: Tet2 antibody at 1 µg/ml. 250 µg of HL-60 whole cell lysate per IP. Tes2 mAb (Clone 21F11) tested by Western blot. Tet2 detection by Western blot. Lane 1: HL-60 whole cell lysate (40 µg). Lane 2: Lymphoblastoid Tet2 negative (-/-) whole cell lysate (40 µg). Lane 3: Lymphoblastoid Tet2 positive (+/+) whole cell lysate (40 µg). All probed with Tet2 antibody at a 1 µg/ml dilution. 100 μg Log in to see 1 to 2 Days
$495.83
Details
Human Goat Un-conjugated IHC, ELISA   100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat lung using TET2 antibody at dilution of 1:100 (40x lens). 100 μL Log in to see 14 Days
$323.13
Details
Human Rabbit Un-conjugated IP, WB 100 μL Log in to see 14 Days
$460.63
Details
Mouse Goat Un-conjugated ELISA   100 μg Log in to see 7 to 9 Days
$419.83
Details

TET2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TET2 Antibodies

  1. Dog (Canine) Polyclonal TET2 Primary Antibody for EIA, IHC (p) - ABIN569654 : Langemeijer, Kuiper, Berends, Knops, Aslanyan, Massop, Stevens-Linders, van Hoogen, van Kessel, Raymakers, Kamping, Verhoef, Verburgh, Hagemeijer, Vandenberghe, de Witte, van der Reijden, Jansen: Acquired mutations in TET2 are common in myelodysplastic syndromes. in Nature genetics 2009 (PubMed)

  2. Human Polyclonal TET2 Primary Antibody for IHC, ELISA - ABIN571057 : Orr, Haffner, Nelson, Yegnasubramanian, Eberhart: Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. in PLoS ONE 2012 (PubMed)

  3. Human Polyclonal TET2 Primary Antibody for EIA, WB - ABIN1450172 : Tefferi, Levine, Lim, Abdel-Wahab, Lasho, Patel, Finke, Mullally, Li, Pardanani, Gilliland: Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates. in Leukemia 2009 (PubMed)

More Antibodies against TET2 Interaction Partners

Human Tet Methylcytosine Dioxygenase 2 (TET2) interaction partners

  1. Deregulated BCL6 (show BCL6 Antibodies) expression caused by hypermethylation and TET2 mutations may result in skewed follicular helper T cell differentiation and eventually contribute to angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma development in patients

  2. Our results confirmed that TET2 is frequently mutated in Taiwanese patients with chronic myelomonocytic leukemia

  3. Endogenous TET2 bound the androgen receptor (AR (show AR Antibodies)) and AR-coactivator proteins in LNCaP cell extracts, and TET2 KD increases prostate-specific antigen (KLK3/PSA (show KLK3 Antibodies)) expression.

  4. TET2 mutation occurred in some populations of DLBCL patients and was likely involved in the pathogenesis of their malignancies

  5. This article focuses mainly on the biological aspects of TET2 mutations, followed by a brief review of recent progress in our understanding of their epigenetic aspects in hematologic malignancies. [review]

  6. We found that TET1 (show TET1 Antibodies) and TET2 messenger RNA expression was lower and TET3 (show TET3 Antibodies) was higher in cancers compared to normal tissues. Positive correlation between 5-hmC and the relative expression of TET1 (show TET1 Antibodies) and TET2 was found, but no correlation was observed in the case of TET3 (show TET3 Antibodies).

  7. review examines mutant IDH1 (show IDH1 Antibodies)/2 and TET2 enzymes in the context of responses to DNA damage and their potential involvement in age-related genomic instability.

  8. Hypermethylation and downregulation of TET2 gene may play a role in predisposition to childhood ALL.

  9. TET2 mutations are likely to be acquired at the common myeloid/lymphoid progenitor levels

  10. this study found a novel hereditary susceptible factor-TET2 rs3733609 C/T variant for the development of Myeloproliferative neoplasms, suggesting the variant may be partially responsible for the pathogenesis and accumulation of Myeloproliferative neoplasms.

Mouse (Murine) Tet Methylcytosine Dioxygenase 2 (TET2) interaction partners

  1. TET2 plays a role in the iron and heme metabolism in erythroblasts.

  2. the effects of vitamin C inhibiting the apo(a (show APOA Antibodies)) expression were attenuated by ELK1siRNA and Tet2siRNA. These results suggested vitamin C down-regulate apo(a (show APOA Antibodies)) expression via Tet2-dependent DNA demethylation in HepG2 cells

  3. Reprogramming of spermatogonial stem cells from Tet1 (show TET1 Antibodies) and Tet2 double knockout mice however lacked demethylation of H19 (show NCKAP1 Antibodies) imprinting control regions.

  4. The critical roles of TET1 (show TET1 Antibodies)/2 individually.

  5. the stability of Foxp3 (show FOXP3 Antibodies) expression is markedly compromised in T reg (show KCNH2 Antibodies) cells from Tet2/Tet3 (show TET3 Antibodies) double-deficient mice.

  6. Tet2 was responsible for increase in 5-hydroxymethylcytosine abundance after ischemic injury.

  7. These results uncover the hypermethylation of DNA methylation (show HELLS Antibodies) canyons as the genomic key feature of Tet1 (show TET1 Antibodies)/Tet2 double-knockout mouse embryonic fibroblasts.

  8. our results indicate that neuronal TET2 is positively involved in the regulation of cell survival.

  9. UNG (show UNG Antibodies) might be involved in Tet-mediated DNA demethylation.

  10. Findings indicate a novel type of hematological malignancy induced by tet oncogene 2 protein (Tet2) loss.

TET2 Antigen Profile

Protein Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TET2

  • tet methylcytosine dioxygenase 2 (TET2) antibody
  • tet methylcytosine dioxygenase 2 (Tet2) antibody
  • Ayu17-449 antibody
  • E130014J05Rik antibody
  • KIAA1546 antibody
  • MDS antibody
  • mKIAA1546 antibody
  • RGD1311625 antibody

Protein level used designations for TET2

methylcytosine dioxygenase TET2 , probable methylcytosine dioxygenase TET2 , tet oncogene family member 2 , tet oncogene 2

GENE ID SPECIES
54790 Homo sapiens
478499 Canis lupus familiaris
214133 Mus musculus
310859 Rattus norvegicus
422540 Gallus gallus
100521465 Sus scrofa
538481 Bos taurus
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